Literature DB >> 26902615

Diverting ileostomy in laparoscopic rectal cancer surgery: high price of protection.

Peter Ihnát1,2, Petra Guňková3,4, Matúš Peteja3,4, Petr Vávra3,4, Anton Pelikán3,4, Pavel Zonča3,4.   

Abstract

BACKGROUND: Anastomotic leakage presents the most feared complication after low anterior resection (LAR). A proximal diversion of the gastrointestinal tract is recommended to avoid septic complications of anastomotic leakage. The aim of the present study was to evaluate the benefits and risks of diverting ileostomy (DI) created during laparoscopic LAR because of low rectal cancer.
METHODS: This was a retrospective clinical cohort study conducted to assess outcomes of laparoscopic LAR with/without DI in a single institution within a 6-year period.
RESULTS: In total, 151 patients were enrolled in the study (73 patients without DI, 78 patients with DI). There were no significant differences between both groups regarding demographic and clinical features. Overall 30-day morbidity rates were significantly lower in patients without DI (23.3 vs. 42.3 %, P = 0.013). Symptomatic anastomotic leakage occurred more frequently in patients without DI (9.6 vs. 2.5 %, P = 0.090); surgical intervention was needed in 6.8 % of patients without DI. Post-operative hospital stay was significantly longer in the group of patients with DI (11.3 ± 8.5 vs. 8.1 ± 6.9 days, P = 0.013). Stoma-related complications occurred in 42 of 78 (53.8 %) patients with DI; some patients had more than one complication. Acute surgery was needed in 9 patients (11.5 %) because of DI-related complications. Small bowel obstruction due to DI semi-rotation around its longitudinal axis was seen in 3 patients (3.8 %) and presents a distinct complication of DI laparoscopic construction. The mean interval between LAR and DI reversal was more than 8 months; only 19.2 % of patients were reversed without delay (≤4 months). Morbidity after DI reversal was 16.6 %; re-laparotomy was necessary in 2.5 % of patients.
CONCLUSIONS: The present study indicates that DI protects low rectal anastomosis from septic complications at a cost of many stoma-related complications, substantial risk of acute surgery necessity and long stoma periods coupled with decreased quality of life.

Entities:  

Keywords:  Anastomotic leakage; Laparoscopy; Low anterior resection; Protective ileostomy; Stoma complications

Mesh:

Year:  2016        PMID: 26902615     DOI: 10.1007/s00464-016-4811-3

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  36 in total

1.  Prospective evaluation of selective defunctioning stoma for low anterior resection with total mesorectal excision.

Authors:  R T Poon; K W Chu; J W Ho; C W Chan; W L Law; J Wong
Journal:  World J Surg       Date:  1999-05       Impact factor: 3.352

2.  Meta-analysis of short-term outcomes after laparoscopic resection for colorectal cancer.

Authors:  N S Abraham; J M Young; M J Solomon
Journal:  Br J Surg       Date:  2004-09       Impact factor: 6.939

Review 3.  The morbidity surrounding reversal of defunctioning ileostomies: a systematic review of 48 studies including 6,107 cases.

Authors:  Andre Chow; Henry S Tilney; Paraskevas Paraskeva; Santhini Jeyarajah; Emmanouil Zacharakis; Sanjay Purkayastha
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4.  The impact of standard protocol implementation on the quality of colorectal cancer pathology reporting.

Authors:  Peter Ihnát; Patricie Delongová; Jaroslav Horáček; Lucia Ihnát Rudinská; Petr Vávra; Pavel Zonča
Journal:  World J Surg       Date:  2015-01       Impact factor: 3.352

Review 5.  Postoperative complications following surgery for rectal cancer.

Authors:  Bogdan C Paun; Scott Cassie; Anthony R MacLean; Elijah Dixon; W Donald Buie
Journal:  Ann Surg       Date:  2010-05       Impact factor: 12.969

6.  Septic complications after low anterior rectal resection--is diverting stoma still justified?

Authors:  B Leester; I Asztalos; C Polnyib
Journal:  Acta Chir Iugosl       Date:  2002

7.  Complications and mortality following stoma formation.

Authors:  D A Harris; D Egbeare; S Jones; H Benjamin; A Woodward; M E Foster
Journal:  Ann R Coll Surg Engl       Date:  2005-11       Impact factor: 1.891

8.  Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial.

Authors:  Pierre J Guillou; Philip Quirke; Helen Thorpe; Joanne Walker; David G Jayne; Adrian M H Smith; Richard M Heath; Julia M Brown
Journal:  Lancet       Date:  2005 May 14-20       Impact factor: 79.321

Review 9.  Increased local recurrence and reduced survival from colorectal cancer following anastomotic leak: systematic review and meta-analysis.

Authors:  Alexander Mirnezami; Reza Mirnezami; Kandiah Chandrakumaran; Kishore Sasapu; Peter Sagar; Paul Finan
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10.  Optimal Treatment Strategy in Rectal Cancer Surgery: Should We Be Cowboys or Chickens?

Authors:  Heleen S Snijders; Nicoline J van Leersum; Daan Henneman; Alexander C de Vries; Rob A E M Tollenaar; Anne M Stiggelbout; Michel W J M Wouters; Jan Willem T Dekker
Journal:  Ann Surg Oncol       Date:  2015-02-18       Impact factor: 5.344

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  29 in total

Review 1.  Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage.

Authors:  Sami A Chadi; Abe Fingerhut; Mariana Berho; Steven R DeMeester; James W Fleshman; Neil H Hyman; David A Margolin; Joseph E Martz; Elisabeth C McLemore; Daniela Molena; Martin I Newman; Janice F Rafferty; Bashar Safar; Anthony J Senagore; Oded Zmora; Steven D Wexner
Journal:  J Gastrointest Surg       Date:  2016-09-16       Impact factor: 3.452

2.  Incidence and predictors of postoperative ileus after loop ileostomy closure: a systematic review and meta-analysis.

Authors:  Richard Garfinkle; Paul Savage; Marylise Boutros; Tara Landry; Pauline Reynier; Nancy Morin; Carol-Ann Vasilevsky; Kristian B Filion
Journal:  Surg Endosc       Date:  2019-04-17       Impact factor: 4.584

3.  Loop ileostomy versus total colectomy as surgical treatment for Clostridium difficile-associated disease: An Eastern Association for the Surgery of Trauma multicenter trial.

Authors:  Paula Ferrada; Rachael Callcut; Martin D Zielinski; Brandon Bruns; Daniel Dante Yeh; Tanya L Zakrison; Jonathan P Meizoso; Babak Sarani; Richard D Catalano; Peter Kim; Valerie Plant; Amelia Pasley; Linda A Dultz; Asad J Choudhry; Elliott R Haut
Journal:  J Trauma Acute Care Surg       Date:  2017-07       Impact factor: 3.313

4.  Who needs diverting ileostomy following laparoscopic low anterior resection in rectal cancer patients? Analysis of 417 patients in a single institute.

Authors:  Hiroki Shimizu; Shigeki Yamaguchi; Toshimasa Ishii; Hiroka Kondo; Kiyoka Hara; Kenichi Takemoto; Shintaro Ishikawa; Takuhisa Okada; Asami Suzuki; Isamu Koyama
Journal:  Surg Endosc       Date:  2019-05-20       Impact factor: 4.584

5.  The impact of transanal tube design for preventing anastomotic leak in anterior resection: a systematic review and meta-analysis.

Authors:  C Dumble; T Morgan; C I Wells; I Bissett; G O'Grady
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6.  The fate of preserved sphincter in rectal cancer patients.

Authors:  Ri Na Yoo; Gun Kim; Bong-Hyeon Kye; Hyeon-Min Cho; HyungJin Kim
Journal:  Int J Colorectal Dis       Date:  2018-03-12       Impact factor: 2.571

7.  Protection of colorectal anastomosis with an intraluminal bypass device for patients undergoing an elective anterior resection: a pilot study.

Authors:  A Reshef; G Ben-Arie; I Pinsk
Journal:  Tech Coloproctol       Date:  2019-07-05       Impact factor: 3.781

8.  When should we add a diverting loop ileostomy to laparoscopic ileocolic resection for primary Crohn's disease?

Authors:  Yong Sik Yoon; Luca Stocchi; Stefan Holubar; Alexandra Aiello; Sherief Shawki; Emre Gorgun; Scott R Steele; Conor P Delaney; Tracy Hull
Journal:  Surg Endosc       Date:  2020-05-28       Impact factor: 4.584

9.  The influence of predictive nursing on the emotions and self-management abilities of post-colostomy rectal cancer patients.

Authors:  Li Li; Lingling Liu; Huiling Kang; Lan Zhang
Journal:  Am J Transl Res       Date:  2021-06-15       Impact factor: 4.060

10.  The effect of a diverting stoma on morbidity and risk of permanent stoma following anastomotic leakage after low anterior resection for rectal cancer: a nationwide cohort study.

Authors:  Nis Hallundbæk Schlesinger; Henry Smith
Journal:  Int J Colorectal Dis       Date:  2020-06-14       Impact factor: 2.571

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