Literature DB >> 268647

Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells.

H Koprowski, W Gerhard, C M Croce.   

Abstract

We have produced somatic cell hybrids between mouse myeloma cells and spleen cells derived from a BALB/c mouse immunized with purified influenza virus. The hybrid cells were found to produce large amounts of antibodies specific for the hemagglutinin of the virus and were able to induce tumor formation when injected into BALB/c mice.

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Year:  1977        PMID： 268647      PMCID： PMC431374          DOI： 10.1073/pnas.74.7.2985

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  16 in total

1.  SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.

Authors:  J W LITTLEFIELD
Journal:  Science       Date:  1964-08-14       Impact factor: 47.728

2.  Persistence of virus-specific memory B cells in mice CNS.

Authors:  W Gerhard; H Koprowski
Journal:  Nature       Date:  1977-03-24       Impact factor: 49.962

3.  Unidirectional loss of human chromosomes in rat-human hybrids.

Authors:  C M Croce; I Kieba; H Koprowski
Journal:  Exp Cell Res       Date:  1973-06       Impact factor: 3.905

4.  Comparison of direct and indirect solid-phase microradioimmunoassays for the detection of viral antigens and antiviral antibody.

Authors:  J D Rosenthal; K Hayashi; A L Notkins
Journal:  Appl Microbiol       Date:  1973-04

5.  The stimulation of splenic foci in vitro.

Authors:  N R Klinman; G Aschinazi
Journal:  J Immunol       Date:  1971-05       Impact factor: 5.422

6.  A rapid banding technique for human chromosomes.

Authors:  M Seabright
Journal:  Lancet       Date:  1971-10-30       Impact factor: 79.321

7.  Production of mammalian somatic cell hybrids by means of polyethylene glycol treatment.

Authors:  G Pontecorvo
Journal:  Somatic Cell Genet       Date:  1975-10

8.  Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol.

Authors:  R L Davidson; P S Gerald
Journal:  Somatic Cell Genet       Date:  1976-03

9.  Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion.

Authors:  G Köhler; C Milstein
Journal:  Eur J Immunol       Date:  1976-07       Impact factor: 5.532

10.  The analysis of the monoclonal immune response to influenza virus. II. The antigenicity of the viral hemagglutinin.

Authors:  W Gerhard
Journal:  J Exp Med       Date:  1976-10-01       Impact factor: 14.307
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  51 in total

1.  Human immune responses to major human cytomegalovirus glycoprotein complexes.

Authors:  Y N Liu; B Kari; R C Gehrz
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

2.  Single amino acid substitutions in the hemagglutinin can alter the host range and receptor binding properties of H1 strains of influenza A virus.

Authors:  S Aytay; I T Schulze
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

3.  Repertoire of antiviral antibodies expressed by somatic cell hybrids.

Authors:  W Gerhard; C M Croce; D Lopes; H Koprowski
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

Review 4.  Monoclonal antibodies. Hybrid myelomas--a revolution in serology and immunogenetics.

Authors:  R G Kennett
Journal:  Am J Hum Genet       Date:  1979-09       Impact factor: 11.025

5.  Production of monoclonal antibodies against nucleocapsid proteins of herpes simplex virus types 1 and 2.

Authors:  M Zweig; C J Heilman; H Rabin; R F Hopkins; R H Neubauer; B Hampar
Journal:  J Virol       Date:  1979-11       Impact factor: 5.103

Review 6.  Monoclonal antibodies: implications for virology. Brief review.

Authors:  K C McCullough
Journal:  Arch Virol       Date:  1986       Impact factor: 2.574

7.  Canine lymphoma-associated antigens defined by murine monoclonal antibodies.

Authors:  Z Steplewski; K A Jeglum; C Rosales; N Weintraub
Journal:  Cancer Immunol Immunother       Date:  1987       Impact factor: 6.968

8.  Studies of mammalian ornithine decarboxylase using a monoclonal antibody.

Authors:  A E Pegg; J E Seely; L Persson; M Herlyn; K Ponsell; T G O'Brien
Journal:  Biochem J       Date:  1984-01-01       Impact factor: 3.857

9.  Human sera possess a limited antibody repertoire to influenza neuraminidase antigenic variants selected in vitro.

Authors:  A Natali; P F Panizzi; C Chezzi; J S Oxford
Journal:  J Hyg (Lond)       Date:  1984-04

10.  Glycoproteins of herpes simplex virus type 2 as defined by monoclonal antibodies.

Authors:  N Balachandran; D Harnish; W E Rawls; S Bacchetti
Journal:  J Virol       Date:  1982-10       Impact factor: 5.103
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