Literature DB >> 2828655

Human immune responses to major human cytomegalovirus glycoprotein complexes.

Y N Liu1, B Kari, R C Gehrz.   

Abstract

Sera from both human cytomegalovirus (HCMV)-seropositive adults and infants with congenital HCMV infection recognized two major HCMV glycoprotein complexes. However, proliferative responses of peripheral blood mononuclear cells to these complexes varied among seropositive adults and were not detected in any of the infants. Thus, these glycoproteins alone may not be sufficient to develop a subviral HCMV vaccine.

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Year:  1988        PMID: 2828655      PMCID: PMC253669          DOI: 10.1128/JVI.62.3.1066-1070.1988

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  28 in total

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Authors:  R C Gehrz; S C Marker; H H Balfour
Journal:  Lancet       Date:  1977-04-09       Impact factor: 79.321

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Journal:  Ann Intern Med       Date:  1975-02       Impact factor: 25.391

6.  Characterization of monoclonal antibodies reactive to several biochemically distinct human cytomegalovirus glycoprotein complexes.

Authors:  B Kari; N Lussenhop; R Goertz; M Wabuke-Bunoti; R Radeke; R Gehrz
Journal:  J Virol       Date:  1986-11       Impact factor: 5.103

7.  Immunity to varicella-zoster viral glycoproteins, gp I (gp 90/58) and gp III (gp 118), and to a nonglycosylated protein, p 170.

Authors:  A M Arvin; E Kinney-Thomas; K Shriver; C Grose; C M Koropchak; E Scranton; A E Wittek; P S Diaz
Journal:  J Immunol       Date:  1986-08-15       Impact factor: 5.422

8.  Viral polypeptides detected by a complement-dependent neutralizing murine monoclonal antibody to human cytomegalovirus.

Authors:  L Rasmussen; J Mullenax; R Nelson; T C Merigan
Journal:  J Virol       Date:  1985-08       Impact factor: 5.103

9.  Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes.

Authors:  J W Yewdell; J R Bennink; G L Smith; B Moss
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

10.  Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralizing antibodies via its expression in recombinant vaccinia virus.

Authors:  M P Cranage; T Kouzarides; A T Bankier; S Satchwell; K Weston; P Tomlinson; B Barrell; H Hart; S E Bell; A C Minson
Journal:  EMBO J       Date:  1986-11       Impact factor: 11.598

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  7 in total

1.  Neutralizing monoclonal antibodies that distinguish three antigenic sites on human cytomegalovirus glycoprotein H have conformationally distinct binding sites.

Authors:  J A Simpson; J C Chow; J Baker; N Avdalovic; S Yuan; D Au; M S Co; M Vasquez; W J Britt; K L Coelingh
Journal:  J Virol       Date:  1993-01       Impact factor: 5.103

2.  Analysis of human antibody responses to human cytomegalovirus envelope glycoproteins found in two families of disulfide linked glycoprotein complexes designated gC-I and gC-II.

Authors:  B Kari; R Gehrz
Journal:  Arch Virol       Date:  1990       Impact factor: 2.574

3.  Characterization of membrane antigens on human cytomegalovirus-infected fibroblasts recognized by human antibodies.

Authors:  L H van der Voort; L F de Leij; T H The
Journal:  J Virol       Date:  1989-03       Impact factor: 5.103

4.  Characterization of cytomegalovirus glycoproteins in a family of complexes designated gC-II with murine monoclonal antibodies.

Authors:  B Kari; R Goertz; R Gehrz
Journal:  Arch Virol       Date:  1990       Impact factor: 2.574

5.  The detection of CMV pp65 and IE1 in glioblastoma multiforme.

Authors:  Kenneth G Lucas; Lei Bao; Richard Bruggeman; Kimberly Dunham; Charles Specht
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6.  Immune mechanisms in congenital cytomegalovirus infection: activation of CMV-specific T helper cells (CMV-Th) by exogenous IL-2.

Authors:  R C Gehrz; E S Peterson; Y N Liu
Journal:  Clin Exp Immunol       Date:  1988-12       Impact factor: 4.330

7.  Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies.

Authors:  M Ohlin; V A Sundqvist; M Mach; B Wahren; C A Borrebaeck
Journal:  J Virol       Date:  1993-02       Impact factor: 5.103

  7 in total

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