Literature DB >> 26840897

N6-methyladenosine–encoded epitranscriptomics.

Nian Liu, Tao Pan.   

Abstract

N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA. Recent discoveries of the locations, functions and mechanisms of m6A have shed light on a new layer of gene regulation at the RNA level, giving rise to the field of m6A epitranscriptomics. In this Perspective, we provide an update on the various effects of mammalian m6A modification, which affects many different stages of the RNA life cycle.

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Year:  2016        PMID： 26840897     DOI： 10.1038/nsmb.3162

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


  69 in total

1.  hnRNP C tetramer measures RNA length to classify RNA polymerase II transcripts for export.

Authors:  Asako McCloskey; Ichiro Taniguchi; Kaori Shinmyozu; Mutsuhito Ohno
Journal:  Science       Date:  2012-03-30       Impact factor: 47.728

2.  N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency.

Authors:  Xiao Wang; Boxuan Simen Zhao; Ian A Roundtree; Zhike Lu; Dali Han; Honghui Ma; Xiaocheng Weng; Kai Chen; Hailing Shi; Chuan He
Journal:  Cell       Date:  2015-06-04       Impact factor: 41.582

3.  m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells.

Authors:  Pedro J Batista; Benoit Molinie; Jinkai Wang; Kun Qu; Jiajing Zhang; Lingjie Li; Donna M Bouley; Ernesto Lujan; Bahareh Haddad; Kaveh Daneshvar; Ava C Carter; Ryan A Flynn; Chan Zhou; Kok-Seong Lim; Peter Dedon; Marius Wernig; Alan C Mullen; Yi Xing; Cosmas C Giallourakis; Howard Y Chang
Journal:  Cell Stem Cell       Date:  2014-10-16       Impact factor: 24.633

4.  Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain.

Authors:  Shukun Luo; Liang Tong
Journal:  Proc Natl Acad Sci U S A       Date:  2014-09-08       Impact factor: 11.205

5.  Sequences containing methylated nucleotides at the 5' termini of messenger RNAs: possible implications for processing.

Authors:  F Rottman; A J Shatkin; R P Perry
Journal:  Cell       Date:  1974-11       Impact factor: 41.582

6.  Precise localization of m6A in Rous sarcoma virus RNA reveals clustering of methylation sites: implications for RNA processing.

Authors:  S E Kane; K Beemon
Journal:  Mol Cell Biol       Date:  1985-09       Impact factor: 4.272

7.  High-resolution N(6) -methyladenosine (m(6) A) map using photo-crosslinking-assisted m(6) A sequencing.

Authors:  Kai Chen; Zhike Lu; Xiao Wang; Ye Fu; Guan-Zheng Luo; Nian Liu; Dali Han; Dan Dominissini; Qing Dai; Tao Pan; Chuan He
Journal:  Angew Chem Int Ed Engl       Date:  2014-12-09       Impact factor: 15.336

Review 8.  The scanning mechanism of eukaryotic translation initiation.

Authors:  Alan G Hinnebusch
Journal:  Annu Rev Biochem       Date:  2014-01-29       Impact factor: 23.643

9.  Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains.

Authors:  Ilmin Kwon; Masato Kato; Siheng Xiang; Leeju Wu; Pano Theodoropoulos; Hamid Mirzaei; Tina Han; Shanhai Xie; Jeffry L Corden; Steven L McKnight
Journal:  Cell       Date:  2013-11-21       Impact factor: 41.582

10.  Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome.

Authors:  Bastian Linder; Anya V Grozhik; Anthony O Olarerin-George; Cem Meydan; Christopher E Mason; Samie R Jaffrey
Journal:  Nat Methods       Date:  2015-06-29       Impact factor: 28.547
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  121 in total

1.  m6A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.

Authors:  Yabing Chen; Jing Wang; Dihui Xu; Zou Xiang; Jie Ding; Xiaoyu Yang; Dongmei Li; Xiaodong Han
Journal:  Autophagy       Date:  2020-01-31       Impact factor: 16.016

Review 2.  Brain Theranostics and Radiotheranostics: Exosomes and Graphenes In Vivo as Novel Brain Theranostics.

Authors:  Minseok Suh; Dong Soo Lee
Journal:  Nucl Med Mol Imaging       Date:  2018-11-09

3.  A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability.

Authors:  Hana Antonicka; Karine Choquet; Zhen-Yuan Lin; Anne-Claude Gingras; Claudia L Kleinman; Eric A Shoubridge
Journal:  EMBO Rep       Date:  2016-12-14       Impact factor: 8.807

4.  Identification of N6-methyladenosine reader proteins.

Authors:  Katherine I Zhou; Nian Liu; Tao Pan
Journal:  Methods       Date:  2017-04-26       Impact factor: 3.608

Review 5.  RNA modification in Cajal bodies.

Authors:  U Thomas Meier
Journal:  RNA Biol       Date:  2016-10-24       Impact factor: 4.652

6.  Quantitative analysis of multilayer organization of proteins and RNA in nuclear speckles at super resolution.

Authors:  Jingyi Fei; Mahdieh Jadaliha; Tyler S Harmon; Isaac T S Li; Boyang Hua; Qinyu Hao; Alex S Holehouse; Matthew Reyer; Qinyu Sun; Susan M Freier; Rohit V Pappu; Kannanganattu V Prasanth; Taekjip Ha
Journal:  J Cell Sci       Date:  2017-11-13       Impact factor: 5.285

7.  Functional Dissection of the m6A RNA Modification.

Authors:  Brooke Huisman; Gabriel Manske; Stephen Carney; Sundeep Kalantry
Journal:  Trends Biochem Sci       Date:  2017-01-04       Impact factor: 13.807

8.  ALKBH5-dependent m6A demethylation controls splicing and stability of long 3'-UTR mRNAs in male germ cells.

Authors:  Chong Tang; Rachel Klukovich; Hongying Peng; Zhuqing Wang; Tian Yu; Ying Zhang; Huili Zheng; Arne Klungland; Wei Yan
Journal:  Proc Natl Acad Sci U S A       Date:  2017-12-26       Impact factor: 11.205

9.  Evolving insights into RNA modifications and their functional diversity in the brain.

Authors:  Sarah Nainar; Paul R Marshall; Christina R Tyler; Robert C Spitale; Timothy W Bredy
Journal:  Nat Neurosci       Date:  2016-09-27       Impact factor: 24.884

10.  Structures of the m(6)A Methyltransferase Complex: Two Subunits with Distinct but Coordinated Roles.

Authors:  Katherine I Zhou; Tao Pan
Journal:  Mol Cell       Date:  2016-07-21       Impact factor: 17.970
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