Literature DB >> 26796427

The conserved molecular machinery in DNA mismatch repair enzyme structures.

Flora S Groothuizen1, Titia K Sixma2.   

Abstract

The machinery of DNA mismatch repair enzymes is highly conserved in evolution. The process is initiated by recognition of a DNA mismatch, and validated by ATP and the presence of a processivity clamp or a methylation mark. Several events in MMR promote conformational changes that lead to progression of the repair process. Here we discuss functional conformational changes in the MMR proteins and we compare the enzymes to paralogs in other systems.
Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  MutH; MutL; MutS; Structure conservation

Mesh：

Substances：

Year:  2015        PMID： 26796427     DOI： 10.1016/j.dnarep.2015.11.012

Source DB:  PubMed          Journal:  DNA Repair (Amst)        ISSN： 1568-7856


  28 in total

1.  The Devil is in the details for DNA mismatch repair.

Authors:  Peggy Hsieh; Yongliang Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2017-03-29       Impact factor: 11.205

2.  MutS sliding clamps on an uncertain track to DNA mismatch repair.

Authors:  Christopher D Putnam
Journal:  Proc Natl Acad Sci U S A       Date:  2020-08-04       Impact factor: 11.205

Review 3.  Eukaryotic Mismatch Repair in Relation to DNA Replication.

Authors:  Thomas A Kunkel; Dorothy A Erie
Journal:  Annu Rev Genet       Date:  2015       Impact factor: 16.830

Review 4.  Endonuclease activities of MutLα and its homologs in DNA mismatch repair.

Authors:  Lyudmila Y Kadyrova; Farid A Kadyrov
Journal:  DNA Repair (Amst)       Date:  2015-12-02

5.  Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair.

Authors:  Nicolaas Hermans; Charlie Laffeber; Michele Cristovão; Mariela Artola-Borán; Yannicka Mardenborough; Pauline Ikpa; Aruna Jaddoe; Herrie H K Winterwerp; Claire Wyman; Josef Jiricny; Roland Kanaar; Peter Friedhoff; Joyce H G Lebbink
Journal:  Nucleic Acids Res       Date:  2016-05-12       Impact factor: 16.971

Review 6.  Roles for mismatch repair family proteins in promoting meiotic crossing over.

Authors:  Carol M Manhart; Eric Alani
Journal:  DNA Repair (Amst)       Date:  2015-12-02

7.  Dynamic human MutSα-MutLα complexes compact mismatched DNA.

Authors:  Kira C Bradford; Hunter Wilkins; Pengyu Hao; Zimeng M Li; Bangchen Wang; Dan Burke; Dong Wu; Austin E Smith; Logan Spaller; Chunwei Du; Jacob W Gauer; Edward Chan; Peggy Hsieh; Keith R Weninger; Dorothy A Erie
Journal:  Proc Natl Acad Sci U S A       Date:  2020-06-25       Impact factor: 11.205

Review 8.  Protecting DNA from errors and damage: an overview of DNA repair mechanisms in plants compared to mammals.

Authors:  Claudia P Spampinato
Journal:  Cell Mol Life Sci       Date:  2016-12-20       Impact factor: 9.261

9.  A PoleP286R mouse model of endometrial cancer recapitulates high mutational burden and immunotherapy response.

Authors:  Hao-Dong Li; Changzheng Lu; He Zhang; Qing Hu; Junqiu Zhang; Ileana C Cuevas; Subhransu S Sahoo; Mitzi Aguilar; Elizabeth G Maurais; Shanrong Zhang; Xiaojing Wang; Esra A Akbay; Guo-Min Li; Bo Li; Prasad Koduru; Peter Ly; Yang-Xin Fu; Diego H Castrillon
Journal:  JCI Insight       Date:  2020-07-23

Review 10.  Mismatch binding, ADP-ATP exchange and intramolecular signaling during mismatch repair.

Authors:  Manju M Hingorani
Journal:  DNA Repair (Amst)       Date:  2015-12-02
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