Literature DB >> 26538685

Arrays of Segmented, Tapered Light Guides for Use with Large, Planar Scintillation Detectors.

Raymond R Raylman1, Keith Vaigneur2, Alexander V Stolin1, Gangadhar Jaliparthi1.   

Abstract

Metabolic imaging techniques can potentially improve detection and diagnosis of cancer in women with radiodense and/or fibrocystic breasts. Our group has previously developed a high-resolution positron emission tomography imaging and biopsy device (PEM-PET) to detect and guide the biopsy of suspicious breast lesions. Initial testing revealed that the imaging field-of-view (FOV) of the scanner was smaller than the physical size of the detector's active area, which could hinder sampling of breast areas close to the chest wall. The purpose of this work was to utilize segmented, tapered light guides for optically coupling the scintillator arrays to arrays of position-sensitive photomultipliers to increase both the active FOV and identification of individual scintillator elements. Testing of the new system revealed that the optics of these structures made it possible to discern detector elements from the complete active area of the detector face. In the previous system the top and bottom rows and left and right columns were not identifiable. Additionally, use of the new light guides increased the contrast of individual detector elements by up to 129%. Improved element identification led to a spatial resolution increase by approximately 12%. Due to attenuation of light in the light guides the detector energy resolution decreased from 18.5% to 19.1%. Overall, these improvements should increase the field-of-view and spatial resolution of the dedicated breast-PET system.

Entities:  

Keywords:  Breast Cancer; Detectors; Nuclear Medicine

Year:  2015        PMID: 26538685      PMCID: PMC4629776          DOI: 10.1109/TNS.2015.2392085

Source DB:  PubMed          Journal:  IEEE Trans Nucl Sci        ISSN: 0018-9499            Impact factor:   1.679


  16 in total

1.  High-resolution scintimammography: a pilot study.

Authors:  Rachel F Brem; Joelle M Schoonjans; Douglas A Kieper; Stan Majewski; Steven Goodman; Cahid Civelek
Journal:  J Nucl Med       Date:  2002-07       Impact factor: 10.057

2.  MicroPET II: design, development and initial performance of an improved microPET scanner for small-animal imaging.

Authors:  Yuan-Chuan Tai; Arion F Chatziioannou; Yongfeng Yang; Robert W Silverman; Ken Meadors; Stefan Siegel; Danny F Newport; Jennifer R Stickel; Simon R Cherry
Journal:  Phys Med Biol       Date:  2003-06-07       Impact factor: 3.609

3.  Physical effects of mechanical design parameters on photon sensitivity and spatial resolution performance of a breast-dedicated PET system.

Authors:  V C Spanoudaki; F W Y Lau; A Vandenbroucke; C S Levin
Journal:  Med Phys       Date:  2010-11       Impact factor: 4.071

4.  Design considerations for a limited angle, dedicated breast, TOF PET scanner.

Authors:  S Surti; J S Karp
Journal:  Phys Med Biol       Date:  2008-05-06       Impact factor: 3.609

5.  Design and evaluation of the MAMMI dedicated breast PET.

Authors:  L Moliner; A J Gonzalez; A Soriano; F Sanchez; C Correcher; A Orero; M Carles; L F Vidal; J Barbera; L Caballero; M Seimetz; C Vazquez; J M Benlloch
Journal:  Med Phys       Date:  2012-09       Impact factor: 4.071

6.  Effect of age and breast density on screening mammograms with false-positive findings.

Authors:  C D Lehman; E White; S Peacock; M J Drucker; N Urban
Journal:  AJR Am J Roentgenol       Date:  1999-12       Impact factor: 3.959

Review 7.  Imaging of the radiographically dense breast.

Authors:  V P Jackson; R E Hendrick; S A Feig; D B Kopans
Journal:  Radiology       Date:  1993-08       Impact factor: 11.105

8.  Feasibility study for positron emission mammography.

Authors:  C J Thompson; K Murthy; I N Weinberg; F Mako
Journal:  Med Phys       Date:  1994-04       Impact factor: 4.071

9.  Detection of primary breast carcinoma with a dedicated, large-field-of-view FDG PET mammography device: initial experience.

Authors:  Eric L Rosen; Timothy G Turkington; Mary Scott Soo; Jay A Baker; R Edward Coleman
Journal:  Radiology       Date:  2005-02       Impact factor: 11.105

10.  Initial clinical test of a breast-PET scanner.

Authors:  Raymond R Raylman; Jame Abraham; Hannah Hazard; Courtney Koren; Shannon Filburn; Judith S Schreiman; Sobha Kurian; Stan Majewski; Gary D Marano
Journal:  J Med Imaging Radiat Oncol       Date:  2011-02       Impact factor: 1.735

View more
  1 in total

1.  A dedicated breast-PET/CT scanner: Evaluation of basic performance characteristics.

Authors:  Raymond R Raylman; Will Van Kampen; Alexander V Stolin; Wenbo Gong; Gangadhar Jaliparthi; Peter F Martone; Mark F Smith; David Sarment; Neal H Clinthorne; Mark Perna
Journal:  Med Phys       Date:  2018-02-23       Impact factor: 4.071

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.