Literature DB >> 26516117

Genes and environment in neonatal intraventricular hemorrhage.

Laura R Ment1, Ulrika Ådén2, Charles R Bauer3, Henrietta S Bada4, Waldemar A Carlo5, Jeffrey R Kaiser6, Aiping Lin7, Charles Michael Cotten8, Jeffrey Murray9, Grier Page10, Mikko Hallman11, Richard P Lifton12, Heping Zhang13.   

Abstract

Emerging data suggest intraventricular hemorrhage (IVH) of the preterm neonate is a complex disorder with contributions from both the environment and the genome. Environmental analyses suggest factors mediating both cerebral blood flow and angiogenesis contribute to IVH, while candidate gene studies report variants in angiogenesis, inflammation, and vascular pathways. Gene-by-environment interactions demonstrate the interaction between the environment and the genome, and a non-replicated genome-wide association study suggests that both environmental and genetic factors contribute to the risk for severe IVH in very low-birth weight preterm neonates.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  GWAS; genes; intraventricular hemorrhage; neonate; preterm

Mesh:

Year:  2015        PMID: 26516117      PMCID: PMC4668116          DOI: 10.1053/j.semperi.2015.09.006

Source DB:  PubMed          Journal:  Semin Perinatol        ISSN: 0146-0005            Impact factor:   3.300


  64 in total

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3.  Replication of genetic associations in the inflammation, complement, and coagulation pathways with intraventricular hemorrhage in LBW preterm neonates.

Authors:  Kelli K Ryckman; John M Dagle; Keegan Kelsey; Allison M Momany; Jeffrey C Murray
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Authors:  Douglas B Gould; F Campbell Phalan; Guido J Breedveld; Saskia E van Mil; Richard S Smith; John C Schimenti; Umberto Aguglia; Marjo S van der Knaap; Peter Heutink; Simon W M John
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5.  Maternal race, demography, and health care disparities impact risk for intraventricular hemorrhage in preterm neonates.

Authors:  Seetha Shankaran; Aiping Lin; Jill Maller-Kesselman; Heping Zhang; T Michael O'Shea; Henrietta S Bada; Jeffrey R Kaiser; Richard P Lifton; Charles R Bauer; Laura R Ment
Journal:  J Pediatr       Date:  2014-02-28       Impact factor: 4.406

6.  Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1993 through December 1994.

Authors:  D K Stevenson; L L Wright; J A Lemons; W Oh; S B Korones; L A Papile; C R Bauer; B J Stoll; J E Tyson; S Shankaran; A A Fanaroff; E F Donovan; R A Ehrenkranz; J Verter
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7.  Very-low-birth-weight outcomes of the National Institute of Child Health and Human Development Neonatal Network, November 1989 to October 1990.

Authors:  M Hack; L L Wright; S Shankaran; J E Tyson; J D Horbar; C R Bauer; N Younes
Journal:  Am J Obstet Gynecol       Date:  1995-02       Impact factor: 8.661

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Authors:  V Tran-Fadulu; H Pannu; D H Kim; G W Vick; C M Lonsford; A L Lafont; C Boccalandro; S Smart; K L Peterson; J Zenger Hain; M C Willing; J S Coselli; S A LeMaire; C Ahn; P H Byers; D M Milewicz
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Review 3.  Prevention and management of bronchopulmonary dysplasia: Lessons learned from the neonatal research network.

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4.  Lack of relationship between cord blood erythropoietin and intraventricular hemorrhage in premature neonates: a controversial result.

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6.  The significance of polymorphisms in genes encoding Il-1β, Il-6, TNFα, and Il-1RN in the pathogenesis of intraventricular hemorrhage in preterm infants.

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9.  Role of Fibronectin-1 polymorphism genes with the pathogenesis of intraventricular hemorrhage in preterm infants.

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10.  Pilot study to establish a prospective neonatal cohort: Study of Preterm Infants and Neurodevelopmental Genes (SPRING).

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