Bonnie A McGregor1,2, Emily D Dolan3, Karly M Murphy4, Timothy S Sannes5, Krista B Highland6, Denise L Albano4, Alison A Ward4, Anna M Charbonneau4, Mary W Redman7, Rachel M Ceballos4,8. 1. Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M3-B232, Seattle, WA, 98109, USA. mcgregor@fredhutch.org. 2. Department of Health Services, School of Public Health and Community Medicine, University of Washington, Seattle, WA, USA. mcgregor@fredhutch.org. 3. Shelter Research and Development, American Society for the Prevention of Cruelty to Animals, New York, NY, USA. 4. Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M3-B232, Seattle, WA, 98109, USA. 5. Anschutz Medical Campus, University of Colorado Denver, Denver, CO, USA. 6. Lombardi Cancer Center, Georgetown University, Washington, DC, USA. 7. Clinical Research, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M3-B232, Seattle, WA, 98109, USA. 8. Department of Health Services, School of Public Health and Community Medicine, University of Washington, Seattle, WA, USA.
Abstract
BACKGROUND: Women at risk for breast cancer report elevated psychological distress, which has been adversely associated with cancer-relevant behaviors and biology. PURPOSE: The present study sought to examine the effects of a 10-week cognitive behavioral stress management (CBSM) group intervention on distress among women with a family history of breast cancer. METHODS: Participants were randomly assigned to CBSM (N = 82) or a wait-list comparison group (N = 76). Baseline to postintervention effects of CBSM on depressive symptoms and perceived stress were examined using hierarchical regression. RESULTS: CBSM participants reported significantly lower posttreatment depressive symptoms (β = -0.17, p < 0.05) and perceived stress (β = -0.23, p < 0.05) than wait-list comparison participants. Additionally, greater relaxation practice predicted lower distress. CONCLUSIONS: Group-based CBSM intervention is feasible and can reduce psychological distress among women with a family history of breast cancer. The present findings represent an encouraging avenue for the future application of CBSM. ( Clinicaltrials.gov number NCT00121160).
RCT Entities:
BACKGROUND:Women at risk for breast cancer report elevated psychological distress, which has been adversely associated with cancer-relevant behaviors and biology. PURPOSE: The present study sought to examine the effects of a 10-week cognitive behavioral stress management (CBSM) group intervention on distress among women with a family history of breast cancer. METHODS:Participants were randomly assigned to CBSM (N = 82) or a wait-list comparison group (N = 76). Baseline to postintervention effects of CBSM on depressive symptoms and perceived stress were examined using hierarchical regression. RESULTS: CBSM participants reported significantly lower posttreatment depressive symptoms (β = -0.17, p < 0.05) and perceived stress (β = -0.23, p < 0.05) than wait-list comparison participants. Additionally, greater relaxation practice predicted lower distress. CONCLUSIONS: Group-based CBSM intervention is feasible and can reduce psychological distress among women with a family history of breast cancer. The present findings represent an encouraging avenue for the future application of CBSM. ( Clinicaltrials.gov number NCT00121160).
Entities:
Keywords:
Breast neoplasms risk; Cognitive behavioral stress management; Distress; Female; Group psychotherapy; Relaxation practice
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