Literature DB >> 26166759

Long non-coding RNAs in innate and adaptive immunity.

Thomas M Aune1, Charles F Spurlock2.   

Abstract

Long noncoding RNAs (lncRNAs) represent a newly discovered class of regulatory molecules that impact a variety of biological processes in cells and organ systems. In humans, it is estimated that there may be more than twice as many lncRNA genes than protein-coding genes. However, only a handful of lncRNAs have been analyzed in detail. In this review, we describe expression and functions of lncRNAs that have been demonstrated to impact innate and adaptive immunity. These emerging paradigms illustrate remarkably diverse mechanisms that lncRNAs utilize to impact the transcriptional programs of immune cells required to fight against pathogens and maintain normal health and homeostasis.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Epigenetics; Immune system; Long non-coding RNA; Transcriptional regulation; Whole genome RNA-sequencing

Mesh:

Substances:

Year:  2015        PMID: 26166759      PMCID: PMC4706828          DOI: 10.1016/j.virusres.2015.07.003

Source DB:  PubMed          Journal:  Virus Res        ISSN: 0168-1702            Impact factor:   3.303


  129 in total

1.  On the origin of cancer cells.

Authors:  O WARBURG
Journal:  Science       Date:  1956-02-24       Impact factor: 47.728

2.  Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation.

Authors:  Juan R Alvarez-Dominguez; Wenqian Hu; Bingbing Yuan; Jiahai Shi; Staphany S Park; Austin A Gromatzky; Alexander van Oudenaarden; Harvey F Lodish
Journal:  Blood       Date:  2013-11-07       Impact factor: 22.113

3.  The eukaryotic genome as an RNA machine.

Authors:  Paulo P Amaral; Marcel E Dinger; Tim R Mercer; John S Mattick
Journal:  Science       Date:  2008-03-28       Impact factor: 47.728

4.  The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.

Authors:  P H Maxwell; M S Wiesener; G W Chang; S C Clifford; E C Vaux; M E Cockman; C C Wykoff; C W Pugh; E R Maher; P J Ratcliffe
Journal:  Nature       Date:  1999-05-20       Impact factor: 49.962

5.  Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.

Authors:  P Jaakkola; D R Mole; Y M Tian; M I Wilson; J Gielbert; S J Gaskell; A von Kriegsheim; H F Hebestreit; M Mukherji; C J Schofield; P H Maxwell; C W Pugh; P J Ratcliffe
Journal:  Science       Date:  2001-04-05       Impact factor: 47.728

Review 6.  lincRNAs: genomics, evolution, and mechanisms.

Authors:  Igor Ulitsky; David P Bartel
Journal:  Cell       Date:  2013-07-03       Impact factor: 41.582

Review 7.  Noncoding RNAs in Long-Term Memory Formation.

Authors:  Tim R Mercer; Marcel E Dinger; Jean Mariani; Kenneth S Kosik; Mark F Mehler; John S Mattick
Journal:  Neuroscientist       Date:  2008-10       Impact factor: 7.519

8.  The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse.

Authors:  Phillip Grote; Lars Wittler; David Hendrix; Frederic Koch; Sandra Währisch; Arica Beisaw; Karol Macura; Gaby Bläss; Manolis Kellis; Martin Werber; Bernhard G Herrmann
Journal:  Dev Cell       Date:  2013-01-28       Impact factor: 12.270

9.  Personalized Oncology Suite: integrating next-generation sequencing data and whole-slide bioimages.

Authors:  Andreas Dander; Matthias Baldauf; Michael Sperk; Stephan Pabinger; Benjamin Hiltpolt; Zlatko Trajanoski
Journal:  BMC Bioinformatics       Date:  2014-09-18       Impact factor: 3.169

10.  HTSeq--a Python framework to work with high-throughput sequencing data.

Authors:  Simon Anders; Paul Theodor Pyl; Wolfgang Huber
Journal:  Bioinformatics       Date:  2014-09-25       Impact factor: 6.937

View more
  37 in total

Review 1.  Role of long non-coding RNAs (LncRNAs) in multiple sclerosis: a brief review.

Authors:  Eskandar Taghizadeh; Forough Taheri; Mohammad Mahdi Samadian; Mohammad Soudyab; Abbas Abi; Seyed Mohammad Gheibi Hayat
Journal:  Neurol Sci       Date:  2020-04-30       Impact factor: 3.307

Review 2.  The emerging regulatory roles of noncoding RNAs in immune function of fish: MicroRNAs versus long noncoding RNAs.

Authors:  Haitham G Abo-Al-Ela
Journal:  Mol Genet Genomics       Date:  2021-04-27       Impact factor: 3.291

3.  Reproductive Long Intergenic Noncoding RNAs Exhibit Male Gamete Specificity and Polycomb Repressive Complex 2-Mediated Repression.

Authors:  Cameron Johnson; Liza J Conrad; Ravi Patel; Sarah Anderson; Chenxin Li; Andy Pereira; Venkatesan Sundaresan
Journal:  Plant Physiol       Date:  2018-05-29       Impact factor: 8.340

Review 4.  Genetic and Molecular Biology of Multiple Sclerosis Among Iranian Patients: An Overview.

Authors:  Meysam Moghbeli
Journal:  Cell Mol Neurobiol       Date:  2019-09-03       Impact factor: 5.046

Review 5.  Biological action in Read-Write genome evolution.

Authors:  James A Shapiro
Journal:  Interface Focus       Date:  2017-08-18       Impact factor: 3.906

Review 6.  Biogenesis and Transcriptional Regulation of Long Noncoding RNAs in the Human Immune System.

Authors:  Charles F Spurlock; Philip S Crooke; Thomas M Aune
Journal:  J Immunol       Date:  2016-12-15       Impact factor: 5.422

7.  Long noncoding RNA SNHG22 increases ZEB1 expression via competitive binding with microRNA-429 to promote the malignant development of papillary thyroid cancer.

Authors:  Hong Gao; Xiaosong Sun; Hongdong Wang; Ying Zheng
Journal:  Cell Cycle       Date:  2020-04-19       Impact factor: 4.534

Review 8.  Long noncoding RNAs in viral infections.

Authors:  Puri Fortes; Kevin V Morris
Journal:  Virus Res       Date:  2015-10-23       Impact factor: 3.303

9.  Long Noncoding RNA ITPRIP-1 Positively Regulates the Innate Immune Response through Promotion of Oligomerization and Activation of MDA5.

Authors:  Qinya Xie; Shengwen Chen; Renyun Tian; Xiang Huang; Rilin Deng; Binbin Xue; Yuwen Qin; Yan Xu; Jingjing Wang; Mengmeng Guo; Jinwen Chen; Songqing Tang; Guangdi Li; Haizhen Zhu
Journal:  J Virol       Date:  2018-08-16       Impact factor: 5.103

10.  Expression Analysis of Long Non-coding RNAs in the Blood of Multiple Sclerosis Patients.

Authors:  Mohammad Mahdi Eftekharian; Soudeh Ghafouri-Fard; Mohammad Soudyab; Mir Davood Omrani; Mahnoosh Rahimi; Arezou Sayad; Alireza Komaki; Mehrdokht Mazdeh; Mohammad Taheri
Journal:  J Mol Neurosci       Date:  2017-10-01       Impact factor: 3.444

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.