| Literature DB >> 25880255 |
Kathrin Thaler-Kall1,2, Annette Peters3, Barbara Thorand4, Eva Grill5, Christine S Autenrieth6, Alexander Horsch7,8,9, Christa Meisinger10,11.
Abstract
BACKGROUND: In this epidemiological study we described the characteristics of spatio-temporal gait parameters among a representative, population-based sample of 890 community-dwelling people aged 65 to 90 years. In addition, we investigated the associations between certain gait parameters and a history of falls in study participants.Entities:
Mesh:
Year: 2015 PMID: 25880255 PMCID: PMC4374293 DOI: 10.1186/s12877-015-0032-1
Source DB: PubMed Journal: BMC Geriatr ISSN: 1471-2318 Impact factor: 3.921
Study sample characteristics by gender (n (percentages) or means (±SD)
| Variable | Males (n = 461) | Females (n = 429) | All (n = 890) | t-value, c2-value, and P Value (t-test/ Chi-square test) |
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| Mean age, y | 75.5 (6.3) | 75.3 (6.2) | 75.4 (6.3) | t(0.59), p = 0.5582 |
| Falls, n (%) | 48 (10.4%) | 71 (16.6%) | 119 (13.4%) | c2(1) = 7.23, p = 0.0072 |
| Recurrent falls, n (%) | 14 (3.0%) | 26 (6.1%) | 40 (4.5%) | c2(2) = 7.92, p = 0.0191 |
| Multimorbidity*, n (%) | 283 (61.4%) | 278 (64.8%) | 561 (63.0%) | c2(1) = 1.11, p = 0.2918 |
| Disability+, n (%) | 70 (15.2%) | 104 (24.2%) | 174 (19.6%) | c2(1) = 11.6, p = 0.0007 |
| Frailty**, n (%) | 176 (38.2%) | 154 (35.9%) | 330 (37.1%) | c2(1) = 0.50, p = 0.4816 |
| Use of ≥ 5 prescribed drugs++, n (%) | 146 (31.7%) | 125 (29.1%) | 271 (30.5%) | c2(1) = 0.67, p = 0.4120 |
| Mean BMI, kg/m2 | 28.3 (3.6) | 28.2 (4.5) | 28.2 (4.1) | t(0.12), p = 0.9061 |
| Mean weight, kg | 82.7 (12.1) | 70.5 (11.9) | 76.8 (13.5) | t(15.25), p < .0001 |
| Mean height, cm | 171 (6.8) | 158 (6.2) | 164.7 (9.2) | t(29.89), p < .0001 |
*According to criteria of Kirchberger et al. [33].
+According to Stanford Health Assessment Questionnaire [34], threshold 0.5 [35].
**Includes pre-frail and frail persons which fulfill at least one criteria of Fried et al. [30-32].
++recorded with IDOM-Software [36].
Gait parameters stratified by history of fall, frailty, multimorbidity, multiple medications and disability status as well as age groups and gender
| Characteristics | Velocity (cm/s) | Cadence (steps/min) | Time (s) | Stride duration* (s) | Stride length (cm) | Normed stride length | Step width (cm) | Normed step width |
|---|---|---|---|---|---|---|---|---|
| Fall participants (n = 119) | 105.5 (24.7) | 106.3 (12.2) | 4.12 (1.29) | 1.14 (0.15) |
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| 8.79 (3.25) | 0.10 (0.04) |
| Non-fall participants (n = 771) | 108.9 (22.9) | 105.4 (13.1) | 3.89 (1.14) | 1.14 (0.16) |
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| 8.73 (3.22) | 0.10 (0.04) |
| t- and p-value | t(−1.43), p = 0.1550 | t(0.77), p = 0.4437 | t(1.83), p = 0.0686 | t(−0.65), p = 0.5170 |
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| t(0.18), p = 0.8541 | t(0.21), p = 0.8310 |
| Frail participants (n = 330) |
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| Non-frail participants (n = 560) |
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| Multimorbid participants (n = 561) |
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| Not multimorbid participants (n = 329) |
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| Disabled participants (n = 174) |
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| Non-disabled participants (n = 716) |
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| Participants taking 5 and more drugs (n = 271) |
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| Participants taking less than 5 drugs (n = 619) |
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| “Young old” (age < 75, n = 410) |
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| “Old Old” (age > = 75, n = 480) |
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| Men (n = 461) |
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| Women (n = 429) |
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*A stride begins with the foot contact and ends with the subsequent foot contact of one foot.
Significant differences are written bold.
Age- and gender-stratified results of logistic regression models for the association between velocity and stride length and history of falls
| Velocity (10 cm/s decrease) | Unadjusted model | Model 1 | Model 2 |
|---|---|---|---|
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| 0.91 (0.78-1.05) | 0.91 (0.77-1.08) | 0.89 (0.75-1.06) |
| Men | 0.97 (0.76-1.24) | 1.06 (0.81-1.38) | 1.06 (0.81-1.39) |
| Women | 0.86 (0.72-1.04) | 0.83 (0.67-1.03) | 0.80 (0.64-1.00) |
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| 1.10 (0.96-1.26) | 1.09 (0.95-1.26) |
| Men |
| 1.18 (0.97-1.43) | 1.16 (0.96-1.42) |
| Women | 1.07 (0.91-1.26) | 1.00 (0.82-1.22) | 1.00 (0.82-1.23) |
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| 0.93 (0.77-1.12) | 0.94 (0.77-1.16) | 0.92 (0.75-1.14) |
| Men | 0.87 (0.64-1.19) | 0.94 (0.67-1.33) | 0.93 (0.65-1.33) |
| Women | 0.82 (0.61-1.10) | 0.77 (0.55-1.07) | 0.70 (0.50-1.00) |
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| Women | 1.18 (0.93-1.50) | 1.10 (0.83-1.47) | 1.08 (0.81-1.45) |
Model 1: adjusted for BMI, disability, frailty.
Model 2: in addition to model 1 adjusted for more than 5 drugs used and multimorbidity.
Significant results are written bold.