Eila Watson1, Bethany Shinkins2, Emma Frith3, David Neal3, Freddie Hamdy4, Fiona Walter5, David Weller6, Clare Wilkinson7, Sara Faithfull8, Jane Wolstenholme9, Prasanna Sooriakumaran4, Christof Kastner3, Christine Campbell6, Richard Neal7, Hugh Butcher10, Mike Matthews10, Rafael Perera2, Peter Rose2. 1. Department of Clinical Health Care, Oxford Brookes University, Oxford, UK. 2. Nuffield Department of Primary Health Care, University of Oxford, Oxford, UK. 3. Department of Surgical Oncology, Cambridge University Hospitals Trust, Cambridge, UK. 4. Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK. 5. Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. 6. Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK. 7. North Wales Centre for Primary Care Research, Bangor University, Bangor, UK. 8. Division of Health and Social Care, University of Surrey, Surrey, UK. 9. Health Economics Research Centre, University of Oxford, Oxford, UK. 10. Service User Representatives, Resident in UK.
Abstract
OBJECTIVE: To explore ongoing symptoms, unmet needs, psychological wellbeing, self-efficacy and overall health status in survivors of prostate cancer. PATIENTS AND METHODS: An invitation to participate in a postal questionnaire survey was sent to 546 men, diagnosed with prostate cancer 9-24 months previously at two UK cancer centres. The study group comprised men who had been subject to a range of treatments: surgery, radiotherapy, hormone therapy and active surveillance. The questionnaire included measures of prostate-related quality of life (Expanded Prostate cancer Index Composite 26-item version, EPIC-26); unmet needs (Supportive Care Needs Survey 34-item version, SCNS-SF34); anxiety and depression (Hospital Anxiety and Depression Scale, HADS), self-efficacy (modified Self-efficacy Scale), health status (EuroQol 5D, EQ-5D) and satisfaction with care (questions developed for this study). A single reminder was sent to non-responders after 3 weeks. Data were analysed by age, co-morbidities, and treatment group. RESULTS: In all, 316 men completed questionnaires (64.1% response rate). Overall satisfaction with follow-up care was high, but was lower for psychosocial than physical aspects of care. Urinary, bowel, and sexual functioning was reported as a moderate/big problem in the last month for 15.2% (n = 48), 5.1% (n = 16), and 36.5% (n = 105) men, respectively. The most commonly reported moderate/high unmet needs related to changes in sexual feelings/relationships, managing fear of recurrence/uncertainty, and concerns about the worries of significant others. It was found that 17% of men (51/307) reported potentially moderate-to-severe levels of anxiety and 10.2% (32/308) reported moderate-to-severe levels of depression. The presence of problematic side-effects was associated with higher psychological morbidity, poorer self-efficacy, greater unmet needs, and poorer overall health status. CONCLUSION: While some men report relatively few problems after prostate cancer treatment, this study highlights important physical and psycho-social issues for a significant minority of survivors of prostate cancer. Strategies for identifying those men with on-going problems, alongside new interventions and models of care, tailored to individual needs, are needed to improve quality of life.
OBJECTIVE: To explore ongoing symptoms, unmet needs, psychological wellbeing, self-efficacy and overall health status in survivors of prostate cancer. PATIENTS AND METHODS: An invitation to participate in a postal questionnaire survey was sent to 546 men, diagnosed with prostate cancer 9-24 months previously at two UK cancer centres. The study group comprised men who had been subject to a range of treatments: surgery, radiotherapy, hormone therapy and active surveillance. The questionnaire included measures of prostate-related quality of life (Expanded Prostate cancer Index Composite 26-item version, EPIC-26); unmet needs (Supportive Care Needs Survey 34-item version, SCNS-SF34); anxiety and depression (Hospital Anxiety and Depression Scale, HADS), self-efficacy (modified Self-efficacy Scale), health status (EuroQol 5D, EQ-5D) and satisfaction with care (questions developed for this study). A single reminder was sent to non-responders after 3 weeks. Data were analysed by age, co-morbidities, and treatment group. RESULTS: In all, 316 men completed questionnaires (64.1% response rate). Overall satisfaction with follow-up care was high, but was lower for psychosocial than physical aspects of care. Urinary, bowel, and sexual functioning was reported as a moderate/big problem in the last month for 15.2% (n = 48), 5.1% (n = 16), and 36.5% (n = 105) men, respectively. The most commonly reported moderate/high unmet needs related to changes in sexual feelings/relationships, managing fear of recurrence/uncertainty, and concerns about the worries of significant others. It was found that 17% of men (51/307) reported potentially moderate-to-severe levels of anxiety and 10.2% (32/308) reported moderate-to-severe levels of depression. The presence of problematic side-effects was associated with higher psychological morbidity, poorer self-efficacy, greater unmet needs, and poorer overall health status. CONCLUSION: While some men report relatively few problems after prostate cancer treatment, this study highlights important physical and psycho-social issues for a significant minority of survivors of prostate cancer. Strategies for identifying those men with on-going problems, alongside new interventions and models of care, tailored to individual needs, are needed to improve quality of life.
Authors: Lauren Matheson; Jo Nayoan; Carol Rivas; Jo Brett; Penny Wright; Hugh Butcher; Paul Jordan; Anna Gavin; Adam Glaser; Malcolm Mason; Richard Wagland; Eila Watson Journal: Support Care Cancer Date: 2020-07-06 Impact factor: 3.603
Authors: Amy Y Zhang; Stephen Ganocy; Alex Z Fu; Denise Kresevic; Lee Ponsky; Gerald Strauss; Donald R Bodner; Hui Zhu Journal: Support Care Cancer Date: 2019-03-22 Impact factor: 3.603
Authors: Qingmei Huang; Ping Jiang; Zijun Zhang; Jie Luo; Yun Dai; Li Zheng; Wei Wang Journal: Support Care Cancer Date: 2017-06-22 Impact factor: 3.603
Authors: Badrinath Konety; Stephen M Zappala; Dipen J Parekh; Danielle Osterhout; Jeffrey Schock; Randy M Chudler; Gregory M Oldford; Kenneth M Kernen; Jason Hafron Journal: Rev Urol Date: 2015