Lauren Matheson1, Jo Nayoan2,3, Carol Rivas2,4, Jo Brett1, Penny Wright5, Hugh Butcher6, Paul Jordan6, Anna Gavin7, Adam Glaser5,8, Malcolm Mason9, Richard Wagland2, Eila Watson10. 1. Oxford School of Nursing and Midwifery, Oxford Brookes University, Oxford, OX3 0FL, UK. 2. Faculty of Health Sciences, University of Southampton, Southampton, SO17 1BJ, UK. 3. European Centre for Environment and Human Health (ECEHH), University of Exeter, Truro, TR1 3HD, UK. 4. Department of Social Science, University College London (UCL), London, WC1H 0NR, UK. 5. Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK. 6. LAPCD user advisory group, Leeds, UK. 7. Northern Ireland Cancer Registry, Centre for Public Health, Queen's University Belfast, Belfast, BT12 6BJ, UK. 8. Leeds Institute of Data Analytics, University of Leeds, Leeds, LS2 9JT, UK. 9. Scool of Medicine, Cardiff University, Cardiff, CF14 2TL, UK. 10. Oxford School of Nursing and Midwifery, Oxford Brookes University, Oxford, OX3 0FL, UK. ewatson@brookes.ac.uk.
Abstract
PURPOSE: Due to recent treatment advances, men are increasingly living longer with advanced prostate cancer (PCa). This study sought to understand men's experiences of living with and adjusting to advanced hormone-responsive PCa and how this influenced their quality of life (QoL), in order to highlight how support could be optimized. METHODS: Participants were recruited through a UK wide survey-the 'Life After Prostate Cancer Diagnosis' study. In-depth telephone interviews were conducted with 24 men (aged 46-77 years) with advanced (stage IV) hormone-responsive PCa diagnosed 18-42 months previously. Thematic analysis was undertaken using a framework approach. RESULTS: Most participants perceived their QoL to be relatively good, which was influenced by the following factors (enablers to 'living well' with PCa): a sense of connectedness to others, engagement in meaningful activities, resources (social, cognitive, financial), ability to manage uncertainty, utilization of adjustment strategies and support, communication and information from health professionals. Barriers to 'living well' with PCa were often the converse of these factors. These also included more troublesome PCa-related symptoms and stronger perceptions of loss and restriction. CONCLUSIONS: In our study, men living with advanced hormone-responsive PCa often reported a good QoL. Exploring the influences on QoL in men with advanced PCa indicates how future interventions might improve the QoL of men who are struggling. Further research is required to develop and test interventions that enhance QoL for these men.
PURPOSE: Due to recent treatment advances, men are increasingly living longer with advanced prostate cancer (PCa). This study sought to understand men's experiences of living with and adjusting to advanced hormone-responsive PCa and how this influenced their quality of life (QoL), in order to highlight how support could be optimized. METHODS:Participants were recruited through a UK wide survey-the 'Life After Prostate Cancer Diagnosis' study. In-depth telephone interviews were conducted with 24 men (aged 46-77 years) with advanced (stage IV) hormone-responsive PCa diagnosed 18-42 months previously. Thematic analysis was undertaken using a framework approach. RESULTS: Most participants perceived their QoL to be relatively good, which was influenced by the following factors (enablers to 'living well' with PCa): a sense of connectedness to others, engagement in meaningful activities, resources (social, cognitive, financial), ability to manage uncertainty, utilization of adjustment strategies and support, communication and information from health professionals. Barriers to 'living well' with PCa were often the converse of these factors. These also included more troublesome PCa-related symptoms and stronger perceptions of loss and restriction. CONCLUSIONS: In our study, men living with advanced hormone-responsive PCa often reported a good QoL. Exploring the influences on QoL in men with advanced PCa indicates how future interventions might improve the QoL of men who are struggling. Further research is required to develop and test interventions that enhance QoL for these men.
Entities:
Keywords:
Advanced; Health care; Metastatic prostate cancer; Patient experience; Qualitative; Quality of life
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Authors: Eila Watson; Bethany Shinkins; Emma Frith; David Neal; Freddie Hamdy; Fiona Walter; David Weller; Clare Wilkinson; Sara Faithfull; Jane Wolstenholme; Prasanna Sooriakumaran; Christof Kastner; Christine Campbell; Richard Neal; Hugh Butcher; Mike Matthews; Rafael Perera; Peter Rose Journal: BJU Int Date: 2015-05-23 Impact factor: 5.588