| Literature DB >> 25798298 |
Daniel J Fechtig1, Branislav Grajciar2, Tilman Schmoll3, Cedric Blatter2, Rene M Werkmeister2, Wolfgang Drexler1, Rainer A Leitgeb1.
Abstract
We demonstrate three-dimensional structural and functional retinal imaging with line-field parallel swept source imaging (LPSI) at acquisition speeds of up to 1 MHz equivalent A-scan rate with sensitivity better than 93.5 dB at a central wavelength of 840 nm. The results demonstrate competitive sensitivity, speed, image contrast and penetration depth when compared to conventional point scanning OCT. LPSI allows high-speed retinal imaging of function and morphology with commercially available components. We further demonstrate a method that mitigates the effect of the lateral Gaussian intensity distribution across the line focus and demonstrate and discuss the feasibility of high-speed optical angiography for visualization of the retinal microcirculation.Entities:
Keywords: (110.4500) Optical coherence tomography; (170.0110) Imaging systems; (170.3880) Medical and biological imaging; (170.4460) Ophthalmic optics and devices
Year: 2015 PMID: 25798298 PMCID: PMC4361428 DOI: 10.1364/BOE.6.000716
Source DB: PubMed Journal: Biomed Opt Express ISSN: 2156-7085 Impact factor: 3.732