Literature DB >> 25798298

Line-field parallel swept source MHz OCT for structural and functional retinal imaging.

Daniel J Fechtig1, Branislav Grajciar2, Tilman Schmoll3, Cedric Blatter2, Rene M Werkmeister2, Wolfgang Drexler1, Rainer A Leitgeb1.   

Abstract

We demonstrate three-dimensional structural and functional retinal imaging with line-field parallel swept source imaging (LPSI) at acquisition speeds of up to 1 MHz equivalent A-scan rate with sensitivity better than 93.5 dB at a central wavelength of 840 nm. The results demonstrate competitive sensitivity, speed, image contrast and penetration depth when compared to conventional point scanning OCT. LPSI allows high-speed retinal imaging of function and morphology with commercially available components. We further demonstrate a method that mitigates the effect of the lateral Gaussian intensity distribution across the line focus and demonstrate and discuss the feasibility of high-speed optical angiography for visualization of the retinal microcirculation.

Entities:  

Keywords:  (110.4500) Optical coherence tomography; (170.0110) Imaging systems; (170.3880) Medical and biological imaging; (170.4460) Ophthalmic optics and devices

Year:  2015        PMID: 25798298      PMCID: PMC4361428          DOI: 10.1364/BOE.6.000716

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN: 2156-7085            Impact factor:   3.732


  44 in total

1.  Multi-megahertz OCT: High quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second.

Authors:  Wolfgang Wieser; Benjamin R Biedermann; Thomas Klein; Christoph M Eigenwillig; Robert Huber
Journal:  Opt Express       Date:  2010-07-05       Impact factor: 3.894

2.  Comparison of phase-shifting techniques for in vivo full-range, high-speed Fourier-domain optical coherence tomography.

Authors:  Dae Yu Kim; John S Werner; Robert J Zawadzki
Journal:  J Biomed Opt       Date:  2010 Sep-Oct       Impact factor: 3.170

3.  Performance of fourier domain vs. time domain optical coherence tomography.

Authors:  R Leitgeb; C Hitzenberger; Adolf Fercher
Journal:  Opt Express       Date:  2003-04-21       Impact factor: 3.894

4.  Motion artifacts in optical coherence tomography with frequency-domain ranging.

Authors:  S H Yun; G Tearney; J de Boer; B Bouma
Journal:  Opt Express       Date:  2004-06-28       Impact factor: 3.894

5.  Parallel Fourier domain optical coherence tomography for in vivo measurement of the human eye.

Authors:  Branislav Grajciar; Michael Pircher; Adolf Fercher; Rainer Leitgeb
Journal:  Opt Express       Date:  2005-02-21       Impact factor: 3.894

6.  Spatially resolved spectral interferometry for determination of subsurface structure.

Authors:  A F Zuluaga; R Richards-Kortum
Journal:  Opt Lett       Date:  1999-04-15       Impact factor: 3.776

7.  Three dimensional optical angiography.

Authors:  Ruikang K Wang; Steven L Jacques; Zhenhe Ma; Sawan Hurst; Stephen R Hanson; Andras Gruber
Journal:  Opt Express       Date:  2007-04-02       Impact factor: 3.894

8.  Megahertz OCT for ultrawide-field retinal imaging with a 1050 nm Fourier domain mode-locked laser.

Authors:  Thomas Klein; Wolfgang Wieser; Christoph M Eigenwillig; Benjamin R Biedermann; Robert Huber
Journal:  Opt Express       Date:  2011-02-14       Impact factor: 3.894

9.  Adaptive optics optical coherence tomography at 1 MHz.

Authors:  Omer P Kocaoglu; Timothy L Turner; Zhuolin Liu; Donald T Miller
Journal:  Biomed Opt Express       Date:  2014-11-06       Impact factor: 3.732

Review 10.  Optical coherence tomography today: speed, contrast, and multimodality.

Authors:  Wolfgang Drexler; Mengyang Liu; Abhishek Kumar; Tschackad Kamali; Angelika Unterhuber; Rainer A Leitgeb
Journal:  J Biomed Opt       Date:  2014       Impact factor: 3.170

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  27 in total

1.  Automated stereo vision instrument tracking for intraoperative OCT guided anterior segment ophthalmic surgical maneuvers.

Authors:  Mohamed T El-Haddad; Yuankai K Tao
Journal:  Biomed Opt Express       Date:  2015-07-23       Impact factor: 3.732

2.  High-performance multi-megahertz optical coherence tomography based on amplified optical time-stretch.

Authors:  Jingjiang Xu; Xiaoming Wei; Luoqin Yu; Chi Zhang; Jianbing Xu; K K Y Wong; Kevin K Tsia
Journal:  Biomed Opt Express       Date:  2015-03-18       Impact factor: 3.732

3.  Flexible A-scan rate MHz-OCT: efficient computational downscaling by coherent averaging.

Authors:  Tom Pfeiffer; Madita Göb; Wolfgang Draxinger; Sebastian Karpf; Jan Philip Kolb; Robert Huber
Journal:  Biomed Opt Express       Date:  2020-10-29       Impact factor: 3.732

4.  Twenty-five years of optical coherence tomography: the paradigm shift in sensitivity and speed provided by Fourier domain OCT [Invited].

Authors:  Johannes F de Boer; Rainer Leitgeb; Maciej Wojtkowski
Journal:  Biomed Opt Express       Date:  2017-06-15       Impact factor: 3.732

5.  Simultaneous multimodal ophthalmic imaging using swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography.

Authors:  Joseph D Malone; Mohamed T El-Haddad; Ivan Bozic; Logan A Tye; Lucas Majeau; Nicolas Godbout; Andrew M Rollins; Caroline Boudoux; Karen M Joos; Shriji N Patel; Yuankai K Tao
Journal:  Biomed Opt Express       Date:  2016-12-12       Impact factor: 3.732

6.  Wide field and highly sensitive angiography based on optical coherence tomography with akinetic swept source.

Authors:  Jingjiang Xu; Shaozhen Song; Wei Wei; Ruikang K Wang
Journal:  Biomed Opt Express       Date:  2016-12-22       Impact factor: 3.732

7.  Ultra-fast line-field low coherence holographic elastography using spatial phase shifting.

Authors:  Chih-Hao Liu; Alexander Schill; Raksha Raghunathan; Chen Wu; Manmohan Singh; Zhaolong Han; Achuth Nair; Kirill V Larin
Journal:  Biomed Opt Express       Date:  2017-01-23       Impact factor: 3.732

Review 8.  High-speed OCT light sources and systems [Invited].

Authors:  Thomas Klein; Robert Huber
Journal:  Biomed Opt Express       Date:  2017-01-13       Impact factor: 3.732

9.  Reduction of frame rate in full-field swept-source optical coherence tomography by numerical motion correction [Invited].

Authors:  Clara Pfäffle; Hendrik Spahr; Dierck Hillmann; Helge Sudkamp; Gesa Franke; Peter Koch; Gereon Hüttmann
Journal:  Biomed Opt Express       Date:  2017-02-13       Impact factor: 3.732

10.  Volumetric optical coherence microscopy with a high space-bandwidth-time product enabled by hybrid adaptive optics.

Authors:  Siyang Liu; Jeffrey A Mulligan; Steven G Adie
Journal:  Biomed Opt Express       Date:  2018-06-15       Impact factor: 3.732

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