Literature DB >> 2570568

Spontaneous excretion of D-alanine in urine in mutant mice lacking D-amino-acid oxidase.

R Konno1, Y Nagata, A Niwa, Y Yasumura.   

Abstract

Urine from mutant mice lacking D-amino-acid oxidase contained a large amount of alanine compared with that from normal mice. Urinary alanine of the mutant mice was sensitive to D-amino-acid oxidase. H.p.l.c. showed that about 94% of the urinary alanine had the D-configuration. These results suggest that D-amino-acid oxidase functions to decompose D-amino acid(s) in normal mice.

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Year:  1989        PMID： 2570568      PMCID： PMC1138815          DOI： 10.1042/bj2610285

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  12 in total

1.  ALANINE: CYCLOSERINE ANTAGONISM. VI. DEMONSTRATION OF D-ALANINE IN THE SERUM OF GUINEA PIGS AND MICE.

Authors:  P D HOEPRICH
Journal:  J Biol Chem       Date:  1965-04       Impact factor: 5.157

2.  Metabolism of amino-acids: Deamination of amino-acids.

Authors:  H A Krebs
Journal:  Biochem J       Date:  1935-07       Impact factor: 3.857

3.  Lack of D-amino-acid oxidase activity causes a specific renal aminoaciduria in the mouse.

Authors:  R Konno; K Isobe; A Niwa; Y Yasumura
Journal:  Biochim Biophys Acta       Date:  1988-12-15

4.  Excessive urinary excretion of methionine in mutant mice lacking D-amino-acid oxidase activity.

Authors:  R Konno; K Isobe; A Niwa; Y Yasumura
Journal:  Metabolism       Date:  1988-12       Impact factor: 8.694

5.  The primary structure of D-amino acid oxidase from pig kidney. II. Isolation and sequence of overlap peptides and the complete sequence.

Authors:  S Ronchi; L Minchiotti; M Galliano; B Curti; R P Swenson; C H Williams; V Massey
Journal:  J Biol Chem       Date:  1982-08-10       Impact factor: 5.157

6.  Molecular cloning and sequence analysis of cDNA encoding human kidney D-amino acid oxidase.

Authors:  K Momoi; K Fukui; F Watanabe; Y Miyake
Journal:  FEBS Lett       Date:  1988-09-26       Impact factor: 4.124

7.  Involvement of D-amino acid oxidase in elimination of free D-amino acids in mice.

Authors:  Y Nagata; R Konno; Y Yasumura; T Akino
Journal:  Biochem J       Date:  1989-01-01       Impact factor: 3.857

8.  Brain and kidney D-amino acid oxidases are coded by a single gene in the mouse.

Authors:  R Konno; Y Yasumura
Journal:  J Neurochem       Date:  1984-02       Impact factor: 5.372

9.  Free D-amino acids in human plasma in relation to senescence and renal diseases.

Authors:  Y Nagata; T Akino; K Ohno; Y Kataoka; T Ueda; T Sakurai; K Shiroshita; T Yasuda
Journal:  Clin Sci (Lond)       Date:  1987-07       Impact factor: 6.124

10.  Molecular cloning and sequence analysis of cDNAs encoding porcine kidney D-amino acid oxidase.

Authors:  K Fukui; F Watanabe; T Shibata; Y Miyake
Journal:  Biochemistry       Date:  1987-06-16       Impact factor: 3.162
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  8 in total

1.  Intestinal bacterial origin of D-alanine in urine of mutant mice lacking D-amino-acid oxidase.

Authors:  R Konno; A Niwa; Y Yasumura
Journal:  Biochem J       Date:  1990-06-01       Impact factor: 3.857

2.  Administration of D-alanine did not cause increase of D-amino acid oxidase activity in mice.

Authors:  Y Nagata; R Yamada; H Nagasaki; R Konno; Y Yasumura
Journal:  Experientia       Date:  1991-08-15

3.  Racemic resolution of some DL-amino acids using Aspergillus fumigatus L-amino acid oxidase.

Authors:  Susmita Singh; Binod K Gogoi; Rajib L Bezbaruah
Journal:  Curr Microbiol       Date:  2011-05-18       Impact factor: 2.188

4.  D-amino acids in mouse tissues are not of microbial origin.

Authors:  Y Nagata; T Akino
Journal:  Experientia       Date:  1990-05-15

5.  Factors controlling the level and determination of D-amino acids in the urine and plasma of laboratory rodents.

Authors:  D W Armstrong; M P Gasper; S H Lee; N Ercal; J Zukowski
Journal:  Amino Acids       Date:  1993-06       Impact factor: 3.520

6.  D-Aminoaciduria in mutant mice lackingD-amino-acid oxidase activity.

Authors:  R Konno; M Ikeda; A Niwa; Y Yasumura
Journal:  Amino Acids       Date:  1991-06       Impact factor: 3.520

7.  D-aspartate oxidase activity and D-aspartate content in a mutant mouse strain lacking D-amino acid oxidase.

Authors:  H Nagasaki; R Yamada; R Konno; Y Yasumura; A Iwashima
Journal:  Experientia       Date:  1990-05-15

Review 8.  Mouse d-Amino-Acid Oxidase: Distribution and Physiological Substrates.

Authors:  Reiko Koga; Yurika Miyoshi; Hiroaki Sakaue; Kenji Hamase; Ryuichi Konno
Journal:  Front Mol Biosci       Date:  2017-12-04
  8 in total

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