Literature DB >> 2901986

Molecular cloning and sequence analysis of cDNA encoding human kidney D-amino acid oxidase.

K Momoi1, K Fukui, F Watanabe, Y Miyake.   

Abstract

cDNA clones encoding D-amino acid oxidase were isolated from a human kidney cDNA library by hybridization with cDNA for the pig enzyme. The cDNA insert of 2.0 kilobase pairs long provided coding information for a protein consisting of 347 amino acids. The molecular mass of the enzyme was calculated to be 39,410 Da. The amino acid sequence similarity between the pig and human enzymes is 84.4%, and among the active site residues proposed from chemical modification studies, methionine-110 of the pig enzyme was replaced by threonine. Northern blot analysis confirmed the expression of an mRNA of 2.0 kilobases encoding the D-amino acid oxidase in human kidney.

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Year:  1988        PMID： 2901986     DOI： 10.1016/0014-5793(88)80252-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  19 in total

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Journal:  Biochem J       Date:  1992-09-15       Impact factor: 3.857

2.  Intestinal bacterial origin of D-alanine in urine of mutant mice lacking D-amino-acid oxidase.

Authors:  R Konno; A Niwa; Y Yasumura
Journal:  Biochem J       Date:  1990-06-01       Impact factor: 3.857

3.  MouseD-amino-acid oxidase gene: Restriction fragment length polymorphism among mouse strains.

Authors:  R Konno; M Sasaki; M Shinohara; J Enami; A Niwa
Journal:  Amino Acids       Date:  1996-06       Impact factor: 3.520

4.  Spontaneous excretion of D-alanine in urine in mutant mice lacking D-amino-acid oxidase.

Authors:  R Konno; Y Nagata; A Niwa; Y Yasumura
Journal:  Biochem J       Date:  1989-07-01       Impact factor: 3.857

5.  cDNA cloning and expression of the flavoprotein D-aspartate oxidase from bovine kidney cortex.

Authors:  T Simonic; S Duga; A Negri; G Tedeschi; M Malcovati; M L Tenchini; S Ronchi
Journal:  Biochem J       Date:  1997-03-15       Impact factor: 3.857

6.  The Therapeutic Potential of D-Amino Acid Oxidase (DAAO) Inhibitors.

Authors:  Sean M Smith; Jason M Uslaner; Peter H Hutson
Journal:  Open Med Chem J       Date:  2010-05-27

7.  Factors controlling the level and determination of D-amino acids in the urine and plasma of laboratory rodents.

Authors:  D W Armstrong; M P Gasper; S H Lee; N Ercal; J Zukowski
Journal:  Amino Acids       Date:  1993-06       Impact factor: 3.520

Review 8.  The neurobiology of D-amino acid oxidase and its involvement in schizophrenia.

Authors:  L Verrall; P W J Burnet; J F Betts; P J Harrison
Journal:  Mol Psychiatry       Date:  2009-09-29       Impact factor: 15.992

9.  Localization of the candidate gene D-amino acid oxidase outside the refined I-cM region of spinocerebellar ataxia 2.

Authors:  S Gispert; A Lunkes; N Santos; G Orozco; D Ha-Hao; T Ratzlaff; J Aguiar; I Torrens; L Heredero; A Brice
Journal:  Am J Hum Genet       Date:  1995-10       Impact factor: 11.025

10.  Potential pathophysiological role of D-amino acid oxidase in schizophrenia: immunohistochemical and in situ hybridization study of the expression in human and rat brain.

Authors:  Koji Ono; Yuji Shishido; Hwan Ki Park; Tomoya Kawazoe; Sanae Iwana; Seong Pil Chung; Rabab M Abou El-Magd; Kazuko Yorita; Mai Okano; Takeshi Watanabe; Nobuya Sano; Yoshimi Bando; Kunimasa Arima; Takashi Sakai; Kiyoshi Fukui
Journal:  J Neural Transm (Vienna)       Date:  2009-08-15       Impact factor: 3.575
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