Literature DB >> 6141223

Brain and kidney D-amino acid oxidases are coded by a single gene in the mouse.

R Konno, Y Yasumura.   

Abstract

Mutant mice (ddY/DAO-) lacking D-amino acid oxidase in the kidney also lacked this enzyme in the brain. Genetic cross experiments showed that the inheritance of the enzyme in the brain was the same as that in the kidney. The deficiency in the enzyme in the brain could not be separated from that in the kidney. The brain and kidney enzymes showed similar substrate specificities. These results suggest that brain and kidney D-amino acid oxidases are coded by the same gene in the mouse.

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Year:  1984        PMID： 6141223     DOI： 10.1111/j.1471-4159.1984.tb02718.x

Source DB:  PubMed          Journal:  J Neurochem        ISSN： 0022-3042            Impact factor:   5.372


  9 in total

1.  Intestinal bacterial origin of D-alanine in urine of mutant mice lacking D-amino-acid oxidase.

Authors:  R Konno; A Niwa; Y Yasumura
Journal:  Biochem J       Date:  1990-06-01       Impact factor: 3.857

2.  Spontaneous excretion of D-alanine in urine in mutant mice lacking D-amino-acid oxidase.

Authors:  R Konno; Y Nagata; A Niwa; Y Yasumura
Journal:  Biochem J       Date:  1989-07-01       Impact factor: 3.857

3.  Administration of D-alanine did not cause increase of D-amino acid oxidase activity in mice.

Authors:  Y Nagata; R Yamada; H Nagasaki; R Konno; Y Yasumura
Journal:  Experientia       Date:  1991-08-15

4.  Involvement of D-amino acid oxidase in elimination of free D-amino acids in mice.

Authors:  Y Nagata; R Konno; Y Yasumura; T Akino
Journal:  Biochem J       Date:  1989-01-01       Impact factor: 3.857

5.  Involvement of D-amino acid oxidase in elimination of D-serine in mouse brain.

Authors:  Y Nagata
Journal:  Experientia       Date:  1992-08-15

6.  D-Aminoaciduria in mutant mice lackingD-amino-acid oxidase activity.

Authors:  R Konno; M Ikeda; A Niwa; Y Yasumura
Journal:  Amino Acids       Date:  1991-06       Impact factor: 3.520

7.  Loss ofHindIII cleavage sites in theD-amino acid oxidase gene in some inbred strains of mice.

Authors:  R Konno; M Sasaki; J Enami; A Niwa
Journal:  Amino Acids       Date:  1995-03       Impact factor: 3.520

Review 8.  Mouse d-Amino-Acid Oxidase: Distribution and Physiological Substrates.

Authors:  Reiko Koga; Yurika Miyoshi; Hiroaki Sakaue; Kenji Hamase; Ryuichi Konno
Journal:  Front Mol Biosci       Date:  2017-12-04

9.  Methods for the Detection of D-Amino-Acid Oxidase.

Authors:  Ryuichi Konno
Journal:  Biol Proced Online       Date:  1998-05-14       Impact factor: 3.244
  9 in total

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