Literature DB >> 25551496

Public health and medical preparedness for a nuclear detonation: the nuclear incident medical enterprise.

C Norman Coleman1, Julie M Sullivan, Judith L Bader, Paula Murrain-Hill, John F Koerner, Andrew L Garrett, David M Weinstock, Cullen Case, Chad Hrdina, Steven A Adams, Robert C Whitcomb, Ellie Graeden, Robert Shankman, Timothy Lant, Bert W Maidment, Richard C Hatchett.   

Abstract

Resilience and the ability to mitigate the consequences of a nuclear incident are enhanced by (1) effective planning, preparation and training; (2) ongoing interaction, formal exercises, and evaluation among the sectors involved; (3) effective and timely response and communication; and (4) continuous improvements based on new science, technology, experience, and ideas. Public health and medical planning require a complex, multi-faceted systematic approach involving federal, state, local, tribal, and territorial governments; private sector organizations; academia; industry; international partners; and individual experts and volunteers. The approach developed by the U.S. Department of Health and Human Services Nuclear Incident Medical Enterprise (NIME) is the result of efforts from government and nongovernment experts. It is a "bottom-up" systematic approach built on the available and emerging science that considers physical infrastructure damage, the spectrum of injuries, a scarce resources setting, the need for decision making in the face of a rapidly evolving situation with limited information early on, timely communication, and the need for tools and just-in-time information for responders who will likely be unfamiliar with radiation medicine and uncertain and overwhelmed in the face of the large number of casualties and the presence of radioactivity. The components of NIME can be used to support planning for, response to, and recovery from the effects of a nuclear incident. Recognizing that it is a continuous work-in-progress, the current status of the public health and medical preparedness and response for a nuclear incident is provided.

Entities:  

Mesh:

Year:  2015        PMID: 25551496      PMCID: PMC4295641          DOI: 10.1097/HP.0000000000000249

Source DB:  PubMed          Journal:  Health Phys        ISSN: 0017-9078            Impact factor:   1.316


  21 in total

1.  Medical management of radiation victims in the United States.

Authors:  Matthew S Davids; Cullen Case; Dennis L Confer; Daniel J Weisdorf; David M Weinstock
Journal:  Health Phys       Date:  2010-06       Impact factor: 1.316

2.  Assessing surge capacity for radiation victims with marrow toxicity.

Authors:  Matthew S Davids; Cullen Case; Raymond Hornung; Nelson J Chao; John P Chute; C Norman Coleman; Daniel Weisdorf; Dennis L Confer; David M Weinstock
Journal:  Biol Blood Marrow Transplant       Date:  2010-04-24       Impact factor: 5.742

3.  Medical response to a radiologic/nuclear event: integrated plan from the Office of the Assistant Secretary for Preparedness and Response, Department of Health and Human Services.

Authors:  C Norman Coleman; Chad Hrdina; Judith L Bader; Ann Norwood; Robert Hayhurst; Joseph Forsha; Kevin Yeskey; Ann Knebel
Journal:  Ann Emerg Med       Date:  2008-04-03       Impact factor: 5.721

4.  Scarce resources for nuclear detonation: project overview and challenges.

Authors:  C Norman Coleman; Ann R Knebel; John L Hick; David M Weinstock; Rocco Casagrande; J Jaime Caro; Evan G DeRenzo; Daniel Dodgen; Ann E Norwood; Susan E Sherman; Kenneth D Cliffer; Richard McNally; Judith L Bader; Paula Murrain-Hill
Journal:  Disaster Med Public Health Prep       Date:  2011-03       Impact factor: 1.385

5.  Triage and treatment tools for use in a scarce resources-crisis standards of care setting after a nuclear detonation.

Authors:  C Norman Coleman; David M Weinstock; Rocco Casagrande; John L Hick; Judith L Bader; Florence Chang; Jeffrey B Nemhauser; Ann R Knebel
Journal:  Disaster Med Public Health Prep       Date:  2011-03       Impact factor: 1.385

6.  Role of dicentric analysis in an overarching biodosimetry strategy for use following a nuclear detonation in an urban environment.

Authors:  Daniel J Blumenthal; Stephen L Sugarman; Doran M Christensen; Albert L Wiley; Gordon K Livingston; Erik S Glassman; John F Koerner; Julie M Sullivan; Sidney Hinds
Journal:  Health Phys       Date:  2014-04       Impact factor: 1.316

7.  The medical decision model and decision maker tools for management of radiological and nuclear incidents.

Authors:  John F Koerner; C Norman Coleman; Paula Murrain-Hill; Denis J FitzGerald; Julie M Sullivan
Journal:  Health Phys       Date:  2014-06       Impact factor: 1.316

8.  The "RTR" medical response system for nuclear and radiological mass-casualty incidents: a functional TRiage-TReatment-TRansport medical response model.

Authors:  Chad M Hrdina; C Norman Coleman; Sandy Bogucki; Judith L Bader; Robert E Hayhurst; Joseph D Forsha; David Marcozzi; Kevin Yeskey; Ann R Knebel
Journal:  Prehosp Disaster Med       Date:  2009 May-Jun       Impact factor: 2.040

Review 9.  Molecular and cellular biology of moderate-dose (1-10 Gy) radiation and potential mechanisms of radiation protection: report of a workshop at Bethesda, Maryland, December 17-18, 2001.

Authors:  C Norman Coleman; William F Blakely; John R Fike; Thomas J MacVittie; Noelle F Metting; James B Mitchell; John E Moulder; R Julian Preston; Thomas M Seed; Helen B Stone; Philip J Tofilon; Rosemary S L Wong
Journal:  Radiat Res       Date:  2003-06       Impact factor: 2.841

10.  Assessment of biodosimetry methods for a mass-casualty radiological incident: medical response and management considerations.

Authors:  Julie M Sullivan; Pataje G S Prasanna; Marcy B Grace; Lynne K Wathen; Rodney L Wallace; John F Koerner; C Norman Coleman
Journal:  Health Phys       Date:  2013-12       Impact factor: 1.316

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  10 in total

1.  The Radiation Stress Response: Of the People, By the People and For the People.

Authors:  C Norman Coleman
Journal:  Radiat Res       Date:  2017-01-24       Impact factor: 2.841

2.  Chemical, Biological, Radiological, Nuclear, and Explosive (CBRNE) Science and the CBRNE Science Medical Operations Science Support Expert (CMOSSE).

Authors:  C Norman Coleman; Judith L Bader; John F Koerner; Chad Hrdina; Kenneth D Cliffer; John L Hick; James J James; Monique K Mansoura; Alicia A Livinski; Scott V Nystrom; Andrea DiCarlo-Cohen; Maria Julia Marinissen; Lynne Wathen; Jessica M Appler; Brooke Buddemeier; Rocco Casagrande; Derek Estes; Patrick Byrne; Edward M Kennedy; Ann A Jakubowski; Cullen Case; David M Weinstock; Nicholas Dainiak; Dan Hanfling; Andrew L Garrett; Natalie N Grant; Daniel Dodgen; Irwin Redlener; Thomas F MacKAY; Meghan Treber; Mary J Homer; Tammy P Taylor; Aubrey Miller; George Korch; Richard Hatchett
Journal:  Disaster Med Public Health Prep       Date:  2019-12       Impact factor: 1.385

3.  Radioprotectors and Radiomitigators for Improving Radiation Therapy: The Small Business Innovation Research (SBIR) Gateway for Accelerating Clinical Translation.

Authors:  Pataje G S Prasanna; Deepa Narayanan; Kory Hallett; Eric J Bernhard; Mansoor M Ahmed; Gregory Evans; Bhadrasain Vikram; Michael Weingarten; C Norman Coleman
Journal:  Radiat Res       Date:  2015-08-18       Impact factor: 2.841

Review 4.  Acute Radiation Syndrome and the Microbiome: Impact and Review.

Authors:  Brynn A Hollingsworth; David R Cassatt; Andrea L DiCarlo; Carmen I Rios; Merriline M Satyamitra; Thomas A Winters; Lanyn P Taliaferro
Journal:  Front Pharmacol       Date:  2021-05-18       Impact factor: 5.810

5.  Biodosimetry: Medicine, Science, and Systems to Support the Medical Decision-Maker Following a Large Scale Nuclear or Radiation Incident.

Authors:  C Norman Coleman; John F Koerner
Journal:  Radiat Prot Dosimetry       Date:  2016-07-29       Impact factor: 0.954

6.  NIH Policies and Regulatory Pathways to U.S. FDA licensure: Strategies to Inform Advancement of Radiation Medical Countermeasures and Biodosimetry Devices.

Authors:  Merriline M Satyamitra; Zulmarie Perez-Horta; Andrea L DiCarlo; David R Cassatt; Carmen I Rios; Paul W Price; Lanyn P Taliaferro
Journal:  Radiat Res       Date:  2022-05-01       Impact factor: 3.372

7.  Preparedness for a 'no-notice' mass-casualty incident: a nuclear detonation scenario.

Authors:  C Norman Coleman; Kenneth D Cliffer; Andrea L DiCarlo; Mary J Homer; Brian R Moyer; Shannon G Loelius; Adam W Tewell; Judith L Bader; John F Koerner
Journal:  Int J Radiat Biol       Date:  2021-12-13       Impact factor: 3.352

Review 8.  The Application of Imaging Flow Cytometry to High-Throughput Biodosimetry.

Authors:  Ruth C Wilkins; Matthew A Rodrigues; Lindsay A Beaton-Green
Journal:  Genome Integr       Date:  2017-01-23

9.  Haptoglobin is an early indicator of survival after radiation-induced severe injury and bone marrow transplantation in mice.

Authors:  Shixiang Zhou; Yaqiong Li; Lexin He; Min Chen; Weihong Li; Ting Xiao; Jian Guan; Zhenhua Qi; Qi Wang; Siyuan Li; Pingkun Zhou; Zhidong Wang
Journal:  Stem Cell Res Ther       Date:  2022-09-06       Impact factor: 8.079

10.  United States medical preparedness for nuclear and radiological emergencies.

Authors:  Andrea L DiCarlo; Mary J Homer; C Norman Coleman
Journal:  J Radiol Prot       Date:  2021-12-06       Impact factor: 1.394

  10 in total

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