Literature DB >> 28118117

The Radiation Stress Response: Of the People, By the People and For the People.

C Norman Coleman1.   

Abstract

The radiation stress response can have broad impact. In this Failla Award presentation it is discussed in three components using terms relevant to the current political season as to how the radiation stress response can be applied to the benefit for cancer care and as service to society. Of the people refers to the impact of radiation on cells, tissues and patients. The paradigm our laboratory uses is radiation as a drug, called "focused biology", and physics as "nano-IMRT" because at the nanometer level physics and biology merge. By the people refers to how the general population often reacts to the word "radiation" and how the Radiation Research Society can better enable society to deal with the current realities of radiation in our lives. For the people refers to the potential for radiation oncology and radiation sciences to improve the lives of millions of people globally who are now beyond benefits of cancer treatment and research.

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Year:  2017        PMID: 28118117      PMCID: PMC5419073          DOI: 10.1667/RR0CNC.1

Source DB:  PubMed          Journal:  Radiat Res        ISSN: 0033-7587            Impact factor:   2.841


  69 in total

Review 1.  The clinical pharmacology of antineoplastic agents (first of two parts).

Authors:  B A Chabner; C E Myers; C N Coleman; D G Johns
Journal:  N Engl J Med       Date:  1975-05-22       Impact factor: 91.245

2.  Radiation oncology: contributions of the United States in the last years of the 20th century.

Authors:  L W Brady; S Kramer; S H Levitt; R G Parker; W E Powers
Journal:  Radiology       Date:  2001-04       Impact factor: 11.105

3.  Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen.

Authors:  S T Palayoor; M Y Youmell; S K Calderwood; C N Coleman; B D Price
Journal:  Oncogene       Date:  1999-12-02       Impact factor: 9.867

4.  Phase I trial of the hypoxic cell cytotoxin tirapazamine with concurrent radiation therapy in the treatment of refractory solid tumors.

Authors:  L N Shulman; L Buswell; N Riese; N Doherty; J S Loeffler; R W von Roemeling; C N Coleman
Journal:  Int J Radiat Oncol Biol Phys       Date:  1999-05-01       Impact factor: 7.038

5.  Tirapazamine: a hypoxia-activated topoisomerase II poison.

Authors:  Katherine B Peters; J Martin Brown
Journal:  Cancer Res       Date:  2002-09-15       Impact factor: 12.701

Review 6.  Linking radiation oncology and imaging through molecular biology (or now that therapy and diagnosis have separated, it's time to get together again!).

Authors:  C Norman Coleman
Journal:  Radiology       Date:  2003-07       Impact factor: 11.105

7.  Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells.

Authors:  Sanjeewani T Palayoor; Philip J Tofilon; C Norman Coleman
Journal:  Clin Cancer Res       Date:  2003-08-01       Impact factor: 12.531

Review 8.  Molecular and cellular biology of moderate-dose (1-10 Gy) radiation and potential mechanisms of radiation protection: report of a workshop at Bethesda, Maryland, December 17-18, 2001.

Authors:  C Norman Coleman; William F Blakely; John R Fike; Thomas J MacVittie; Noelle F Metting; James B Mitchell; John E Moulder; R Julian Preston; Thomas M Seed; Helen B Stone; Philip J Tofilon; Rosemary S L Wong
Journal:  Radiat Res       Date:  2003-06       Impact factor: 2.841

9.  The efficacy of pharmacokinetic monitoring and dose modification of etanidazole on the incidence of neurotoxicity: results from a phase II trial of etanidazole and radiation therapy in locally advanced prostate cancer.

Authors:  C N Coleman; L Buswell; L Noll; N Riese; M A Rose
Journal:  Int J Radiat Oncol Biol Phys       Date:  1992       Impact factor: 7.038

10.  Phase III study of ibuprofen versus placebo for radiation-induced genitourinary side effects.

Authors:  C Norman Coleman; Laura Kelly; Nancy Riese Daly; Clair Beard; Irving Kaplan; Carolyn Lamb; Kathleen Propert; Judith Manola
Journal:  Int J Radiat Oncol Biol Phys       Date:  2002-09-01       Impact factor: 7.038

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  1 in total

1.  Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome.

Authors:  Isabelle R Miousse; Laura E Ewing; Charles M Skinner; Rupak Pathak; Sarita Garg; Kristy R Kutanzi; Stepan Melnyk; Martin Hauer-Jensen; Igor Koturbash
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2020-01-21       Impact factor: 4.052

  1 in total

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