Literature DB >> 27473694

Biodosimetry: Medicine, Science, and Systems to Support the Medical Decision-Maker Following a Large Scale Nuclear or Radiation Incident.

C Norman Coleman1,2, John F Koerner3.   

Abstract

The public health and medical response to a radiological or nuclear incident requires the capability to sort, assess, treat, triage and to ultimately discharge, refer or transport people to their next step in medical care. The size of the incident and scarcity of resources at the location of each medical decision point will determine how patients are triaged and treated. This will be a rapidly evolving situation impacting medical responders at regional, national and international levels. As capabilities, diagnostics and medical countermeasures improve, a dynamic system-based approach is needed to plan for and manage the incident, and to adapt effectively in real time. In that the concepts and terms can be unfamiliar and possibly confusing, resources and a concept of operations must be considered well in advance. An essential underlying tenet is that medical evaluation and care will be managed by healthcare professionals with biodosimetry assays providing critical supporting data. Published by Oxford University Press 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Entities:  

Mesh:

Year:  2016        PMID: 27473694      PMCID: PMC6061193          DOI: 10.1093/rpd/ncw155

Source DB:  PubMed          Journal:  Radiat Prot Dosimetry        ISSN: 0144-8420            Impact factor:   0.954


  17 in total

1.  The 2007 Recommendations of the International Commission on Radiological Protection. ICRP publication 103.

Authors: 
Journal:  Ann ICRP       Date:  2007

2.  Critical issues in preparing for a mass casualty event: highlights from a new community planning guide.

Authors: 
Journal:  Biosecur Bioterror       Date:  2007-09

3.  Radiologic and nuclear events: the METREPOL severity of effect grading system.

Authors:  Theodor M Fliedner; Ray Powles; Bhawna Sirohi; Dietger Niederwieser
Journal:  Blood       Date:  2008-06-15       Impact factor: 22.113

4.  Scarce resources for nuclear detonation: project overview and challenges.

Authors:  C Norman Coleman; Ann R Knebel; John L Hick; David M Weinstock; Rocco Casagrande; J Jaime Caro; Evan G DeRenzo; Daniel Dodgen; Ann E Norwood; Susan E Sherman; Kenneth D Cliffer; Richard McNally; Judith L Bader; Paula Murrain-Hill
Journal:  Disaster Med Public Health Prep       Date:  2011-03       Impact factor: 1.385

5.  Triage and treatment tools for use in a scarce resources-crisis standards of care setting after a nuclear detonation.

Authors:  C Norman Coleman; David M Weinstock; Rocco Casagrande; John L Hick; Judith L Bader; Florence Chang; Jeffrey B Nemhauser; Ann R Knebel
Journal:  Disaster Med Public Health Prep       Date:  2011-03       Impact factor: 1.385

6.  Allocation of scarce resources after a nuclear detonation: setting the context.

Authors:  Ann R Knebel; C Norman Coleman; Kenneth D Cliffer; Paula Murrain-Hill; Richard McNally; Victor Oancea; Jimmie Jacobs; Brooke Buddemeier; John L Hick; David M Weinstock; Chad M Hrdina; Tammy Taylor; Marianne Matzo; Judith L Bader; Alicia A Livinski; Gerald Parker; Kevin Yeskey
Journal:  Disaster Med Public Health Prep       Date:  2011-03       Impact factor: 1.385

7.  User-managed inventory: an approach to forward-deployment of urgently needed medical countermeasures for mass-casualty and terrorism incidents.

Authors:  C Norman Coleman; Chad Hrdina; Rocco Casagrande; Kenneth D Cliffer; Monique K Mansoura; Scott Nystrom; Richard Hatchett; J Jaime Caro; Ann R Knebel; Katherine S Wallace; Steven A Adams
Journal:  Disaster Med Public Health Prep       Date:  2012-12       Impact factor: 1.385

8.  The medical decision model and decision maker tools for management of radiological and nuclear incidents.

Authors:  John F Koerner; C Norman Coleman; Paula Murrain-Hill; Denis J FitzGerald; Julie M Sullivan
Journal:  Health Phys       Date:  2014-06       Impact factor: 1.316

9.  Public health and medical preparedness for a nuclear detonation: the nuclear incident medical enterprise.

Authors:  C Norman Coleman; Julie M Sullivan; Judith L Bader; Paula Murrain-Hill; John F Koerner; Andrew L Garrett; David M Weinstock; Cullen Case; Chad Hrdina; Steven A Adams; Robert C Whitcomb; Ellie Graeden; Robert Shankman; Timothy Lant; Bert W Maidment; Richard C Hatchett
Journal:  Health Phys       Date:  2015-02       Impact factor: 1.316

10.  Resource allocation after a nuclear detonation incident: unaltered standards of ethical decision making.

Authors:  J Jaime Caro; Evan G DeRenzo; C Norman Coleman; David M Weinstock; Ann R Knebel
Journal:  Disaster Med Public Health Prep       Date:  2011-03       Impact factor: 1.385

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  21 in total

1.  Microarray analysis of miRNA expression profiles following whole body irradiation in a mouse model.

Authors:  Molykutty J Aryankalayil; Sunita Chopra; Adeola Makinde; Iris Eke; Joel Levin; Uma Shankavaram; Laurel MacMillan; Claire Vanpouille-Box; Sandra Demaria; C Norman Coleman
Journal:  Biomarkers       Date:  2018-06-19       Impact factor: 2.658

2.  Biodosimetry: A Future Tool for Medical Management of Radiological Emergencies.

Authors:  Mary T Sproull; Kevin A Camphausen; Gregory D Koblentz
Journal:  Health Secur       Date:  2017-12-01

Review 3.  Using Stable Free Radicals to Obtain Unique and Clinically Useful Data In Vivo in Human Subjects.

Authors:  Harold M Swartz
Journal:  Radiat Prot Dosimetry       Date:  2016-11-24       Impact factor: 0.972

4.  Metabolic Dysregulation after Neutron Exposures Expected from an Improvised Nuclear Device.

Authors:  Evagelia C Laiakis; Yi-Wen Wang; Erik F Young; Andrew D Harken; Yanping Xu; Lubomir Smilenov; Guy Y Garty; David J Brenner; Albert J Fornace
Journal:  Radiat Res       Date:  2017-05-05       Impact factor: 2.841

5.  Developments in Biodosimetry Methods for Triage With a Focus on X-band Electron Paramagnetic Resonance In Vivo Fingernail Dosimetry.

Authors:  Steven G Swarts; Jason W Sidabras; Oleg Grinberg; Dmitriy S Tipikin; Maciej M Kmiec; Sergey V Petryakov; Wilson Schreiber; Victoria A Wood; Benjamin B Williams; Ann Barry Flood; Harold M Swartz
Journal:  Health Phys       Date:  2018-07       Impact factor: 1.316

6.  Development of a novel mouth model as an alternative tool to test the effectiveness of an in vivo EPR dosimetry system.

Authors:  Kyo Kobayashi; Ruhong Dong; Roberto Javier Nicolalde; Paul Calderon; Gaixin Du; Benjamin B Williams; Masaichi-Chang-Il Lee; Harold M Swartz; Ann Barry Flood
Journal:  Phys Med Biol       Date:  2018-08-10       Impact factor: 3.609

7.  Gene Expression in Parp1 Deficient Mice Exposed to a Median Lethal Dose of Gamma Rays.

Authors:  M A Suresh Kumar; Evagelia C Laiakis; Shanaz A Ghandhi; Shad R Morton; Albert J Fornace; Sally A Amundson
Journal:  Radiat Res       Date:  2018-05-10       Impact factor: 2.841

8.  Gene Expression Profiles from Heart, Lung and Liver Samples of Total-Body-Irradiated Minipigs: Implications for Predicting Radiation-Induced Tissue Toxicity.

Authors:  Sunita Chopra; Maria Moroni; Shannon Martello; Michelle Bylicky; Jared May; Bernadette Hritzo; Laurel MacMillan; C Norman Coleman; Molykutty J Aryankalayil
Journal:  Radiat Res       Date:  2020-10-02       Impact factor: 2.841

9.  Small Molecule Responses to Sequential Irradiation with Neutrons and Photons for Biodosimetry Applications: An Initial Assessment.

Authors:  Evagelia C Laiakis; Monica Pujol Canadell; Veljko Grilj; Andrew D Harken; Guy Y Garty; David J Brenner; Lubomir Smilenov; Albert J Fornace
Journal:  Radiat Res       Date:  2021-11-01       Impact factor: 2.841

10.  Dose and Dose-Rate Effects in a Mouse Model of Internal Exposure to 137Cs. Part 1: Global Transcriptomic Responses in Blood.

Authors:  Shanaz A Ghandhi; Chao Sima; Waylon M Weber; Dunstana R Melo; Nils Rudqvist; Shad R Morton; Helen C Turner; Sally A Amundson
Journal:  Radiat Res       Date:  2020-11-01       Impact factor: 2.841

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