Literature DB >> 25523111

Genetic counselors' (GC) knowledge, awareness, understanding of clinical next-generation sequencing (NGS) genomic testing.

P M Boland1, K Ruth2, J M Matro2, K L Rainey2, C Y Fang2, Y N Wong2, M B Daly2, M J Hall2.   

Abstract

Genomic tests are increasingly complex, less expensive, and more widely available with the advent of next-generation sequencing (NGS). We assessed knowledge and perceptions among genetic counselors pertaining to NGS genomic testing via an online survey. Associations between selected characteristics and perceptions were examined. Recent education on NGS testing was common, but practical experience limited. Perceived understanding of clinical NGS was modest, specifically concerning tumor testing. Greater perceived understanding of clinical NGS testing correlated with more time spent in cancer-related counseling, exposure to NGS testing, and NGS-focused education. Substantial disagreement about the role of counseling for tumor-based testing was seen. Finally, a majority of counselors agreed with the need for more education about clinical NGS testing, supporting this approach to optimizing implementation.
© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  genetic counseling; next-generation sequencing; preparedness

Mesh:

Year:  2015        PMID: 25523111      PMCID: PMC4474774          DOI: 10.1111/cge.12555

Source DB:  PubMed          Journal:  Clin Genet        ISSN: 0009-9163            Impact factor:   4.438


  17 in total

1.  Consent and privacy in pharmacogenetic testing.

Authors:  J A Robertson
Journal:  Nat Genet       Date:  2001-07       Impact factor: 38.330

Review 2.  Informed consent: not just for procedures anymore.

Authors:  Andrew D Feld
Journal:  Am J Gastroenterol       Date:  2004-06       Impact factor: 10.864

Review 3.  From pharmacogenetics to personalized medicine: a vital need for educating health professionals and the community.

Authors:  Felix W Frueh; David Gurwitz
Journal:  Pharmacogenomics       Date:  2004-07       Impact factor: 2.533

4.  Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education.

Authors:  D Gurwitz; J E Lunshof; G Dedoussis; C S Flordellis; U Fuhr; J Kirchheiner; J Licinio; A Llerena; V G Manolopoulos; L J Sheffield; G Siest; F Torricelli; V Vasiliou; S Wong
Journal:  Pharmacogenomics J       Date:  2005       Impact factor: 3.550

5.  Pharmacogenetics and pharmacogenomics instruction in schools of pharmacy in the USA: is it adequate?

Authors:  David A Latif
Journal:  Pharmacogenomics       Date:  2005-06       Impact factor: 2.533

6.  Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

Authors:  Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde
Journal:  J Biomed Inform       Date:  2008-09-30       Impact factor: 6.317

7.  Patients' and healthcare professionals' views on pharmacogenetic testing and its future delivery in the NHS.

Authors:  Emily A Fargher; Charlotte Eddy; William Newman; Faieza Qasim; Karen Tricker; Rachel A Elliott; Katherine Payne
Journal:  Pharmacogenomics       Date:  2007-11       Impact factor: 2.533

8.  Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays.

Authors:  Radoje Drmanac; Andrew B Sparks; Matthew J Callow; Aaron L Halpern; Norman L Burns; Bahram G Kermani; Paolo Carnevali; Igor Nazarenko; Geoffrey B Nilsen; George Yeung; Fredrik Dahl; Andres Fernandez; Bryan Staker; Krishna P Pant; Jonathan Baccash; Adam P Borcherding; Anushka Brownley; Ryan Cedeno; Linsu Chen; Dan Chernikoff; Alex Cheung; Razvan Chirita; Benjamin Curson; Jessica C Ebert; Coleen R Hacker; Robert Hartlage; Brian Hauser; Steve Huang; Yuan Jiang; Vitali Karpinchyk; Mark Koenig; Calvin Kong; Tom Landers; Catherine Le; Jia Liu; Celeste E McBride; Matt Morenzoni; Robert E Morey; Karl Mutch; Helena Perazich; Kimberly Perry; Brock A Peters; Joe Peterson; Charit L Pethiyagoda; Kaliprasad Pothuraju; Claudia Richter; Abraham M Rosenbaum; Shaunak Roy; Jay Shafto; Uladzislau Sharanhovich; Karen W Shannon; Conrad G Sheppy; Michel Sun; Joseph V Thakuria; Anne Tran; Dylan Vu; Alexander Wait Zaranek; Xiaodi Wu; Snezana Drmanac; Arnold R Oliphant; William C Banyai; Bruce Martin; Dennis G Ballinger; George M Church; Clifford A Reid
Journal:  Science       Date:  2009-11-05       Impact factor: 47.728

9.  ACOG Committee Opinion No. 410: Ethical issues in genetic testing.

Authors: 
Journal:  Obstet Gynecol       Date:  2008-06       Impact factor: 7.661

10.  Information preferences of high literacy pregnant women regarding informed consent models for genetic carrier screening.

Authors:  K E Ormond; S Banuvar; A Daly; M Iris; J Minogue; S Elias
Journal:  Patient Educ Couns       Date:  2008-11-14
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  4 in total

1.  Cancer Genetic Counselors' Current Practices and Attitudes Related to the Use of Tumor Profiling.

Authors:  LeAnne Noelle Goedde; Nathan W Stupiansky; Melissa Lah; Kimberly A Quaid; Stephanie Cohen
Journal:  J Genet Couns       Date:  2017-01-13       Impact factor: 2.537

2.  Patients' Expectations of Benefits From Large-Panel Genomic Tumor Testing in Rural Community Oncology Practices.

Authors:  Eric C Anderson; John DiPalazzo; Emily Edelman; Petra Helbig; Kate Reed; Susan Miesfeldt; Christian Thomas; F Lee Lucas; Anny T H R Fenton; Andrey Antov; Michael J Hall; J Scott Roberts; Jens Rueter; Paul K J Han
Journal:  JCO Precis Oncol       Date:  2021-09-29

Review 3.  Molecular Pathology and Personalized Medicine: The Dawn of a New Era in Companion Diagnostics-Practical Considerations about Companion Diagnostics for Non-Small-Cell-Lung-Cancer.

Authors:  Till Plönes; Walburga Engel-Riedel; Erich Stoelben; Christina Limmroth; Oliver Schildgen; Verena Schildgen
Journal:  J Pers Med       Date:  2016-01-15

4.  The genetic background of Southern Iranian couples before marriage.

Authors:  A Nariman; M R Sobhan; M Savaei; E Aref-Eshghi; R Nourinejad; M Manoochehri; S Ghahremani; F Daliri; K Daliri
Journal:  Balkan J Med Genet       Date:  2017-03-04       Impact factor: 0.519

  4 in total

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