Literature DB >> 15212593

From pharmacogenetics to personalized medicine: a vital need for educating health professionals and the community.

Felix W Frueh1, David Gurwitz.   

Abstract

The field of pharmacogenetics will soon celebrate its 50th anniversary. Although science has delivered an impressive amount of information in these 50 years, pharmacogenetics has suffered from lack of integration into clinical practice. There are several reasons for this, including the unmet need for education at medical schools and the lack of awareness about the impact of genetic medicine on healthcare in the community. Recently, the FDA announced that it considers pharmacogenomics one of three major opportunities on the critical path to new medical products. This notion by the FDA is filling the regulatory void that existed between drug developers and drug users. However, in order to bring pharmacogenetic testing to the prescription pad successfully, healthcare professionals and policy makers, as well as patients, need to have the necessary background knowledge for making educated treatment decisions. To effectively move pharmacogenetics into everyday medicine, it is therefore imperative for scientists and teachers in the field to take on the challenge of disseminating pharmacogenetic insights to a broader audience.

Entities:  

Mesh:

Year:  2004        PMID: 15212593     DOI: 10.1517/14622416.5.5.571

Source DB:  PubMed          Journal:  Pharmacogenomics        ISSN: 1462-2416            Impact factor:   2.533


  26 in total

1.  Delivering a pharmacogenetic service: is there a role for genetic counselors?

Authors:  Alice Callard; William Newman; Katherine Payne
Journal:  J Genet Couns       Date:  2011-11-04       Impact factor: 2.537

2.  Transforming the practice of medicine using genomics.

Authors:  Geoffrey S Ginsburg; Geoffrey S Ginsburg; Jeanette J McCarthy
Journal:  Clin Cases Miner Bone Metab       Date:  2009-01

3.  Clinician adoption of genetic testing for drug metabolizing enzymes: is patient safety the low-hanging fruit of personalized medicine?

Authors:  Harry Enchin
Journal:  AMIA Annu Symp Proc       Date:  2009-11-14

Review 4.  Recent progress and clinical importance on pharmacogenetics in cancer therapy.

Authors:  Thomas I Peng Soh; Wei Peng Yong; Federico Innocenti
Journal:  Clin Chem Lab Med       Date:  2011-09-28       Impact factor: 3.694

Review 5.  Therapeutic drug monitoring and pharmacogenetic tests as tools in pharmacovigilance.

Authors:  Eveline Jaquenoud Sirot; Jan Willem van der Velden; Katharina Rentsch; Chin B Eap; Pierre Baumann
Journal:  Drug Saf       Date:  2006       Impact factor: 5.606

6.  Genomic Medicine: 'grand challenges' in the translation of genomics to human health.

Authors:  Geoffrey S Ginsburg
Journal:  Eur J Hum Genet       Date:  2008-06-18       Impact factor: 4.246

7.  Parents' attitudes toward pediatric genetic testing for common disease risk.

Authors:  Kenneth P Tercyak; Sharon Hensley Alford; Karen M Emmons; Isaac M Lipkus; Benjamin S Wilfond; Colleen M McBride
Journal:  Pediatrics       Date:  2011-04-18       Impact factor: 7.124

Review 8.  Genetic diversity and medicinal drug response in eye care.

Authors:  Barkur S Shastry
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2010-03-05       Impact factor: 3.117

Review 9.  The Routine Clinical use of Pharmacogenetic Tests: What it Will Require?

Authors:  Mafalda M Dias; Michael J Sorich; Andrew Rowland; Michael D Wiese; Ross A McKinnon
Journal:  Pharm Res       Date:  2017-02-24       Impact factor: 4.200

10.  Risk assessment and communication tools for genotype associations with multifactorial phenotypes: the concept of "edge effect" and cultivating an ethical bridge between omics innovations and society.

Authors:  Vural Ozdemir; Guilherme Suarez-Kurtz; Raphaëlle Stenne; Andrew A Somogyi; Toshiyuki Someya; S Oğuz Kayaalp; Eugene Kolker
Journal:  OMICS       Date:  2009-02
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.