Literature DB >> 25461450

Chemical approaches to cell reprogramming.

Chen Yu1, Kai Liu1, Shibing Tang1, Sheng Ding1.   

Abstract

Recent advances in cell reprogramming via employing different sets of factors, which allows generation of various cell types that are beyond the downstream developmental lineages from the starting cell type, provide significant opportunities to study fundamental biology and hold enormous promise in regenerative medicine. Small molecules have been identified to enhance and enable reprogramming by regulating various mechanisms, and provide a highly temporal and tunable approach to modulate cellular fate and functions. Here, we review the latest development in cell reprogramming from the perspective of small molecule modulation.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25461450      PMCID： PMC4747244          DOI： 10.1016/j.gde.2014.09.006

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  55 in total

1.  Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds.

Authors:  Pingping Hou; Yanqin Li; Xu Zhang; Chun Liu; Jingyang Guan; Honggang Li; Ting Zhao; Junqing Ye; Weifeng Yang; Kang Liu; Jian Ge; Jun Xu; Qiang Zhang; Yang Zhao; Hongkui Deng
Journal:  Science       Date:  2013-07-18       Impact factor: 47.728

Review 2.  Chemical approaches to stem cell biology and therapeutics.

Authors:  Wenlin Li; Ke Li; Wanguo Wei; Sheng Ding
Journal:  Cell Stem Cell       Date:  2013-09-05       Impact factor: 24.633

3.  Transient activation of autophagy via Sox2-mediated suppression of mTOR is an important early step in reprogramming to pluripotency.

Authors:  Shuo Wang; Pengyan Xia; Buqing Ye; Guanling Huang; Jing Liu; Zusen Fan
Journal:  Cell Stem Cell       Date:  2013-11-07       Impact factor: 24.633

4.  Hypoxia enhances the generation of induced pluripotent stem cells.

Authors:  Yoshinori Yoshida; Kazutoshi Takahashi; Keisuke Okita; Tomoko Ichisaka; Shinya Yamanaka
Journal:  Cell Stem Cell       Date:  2009-08-27       Impact factor: 24.633

5.  Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4.

Authors:  Haixia Wang; Nan Cao; C Ian Spencer; Baoming Nie; Tianhua Ma; Tao Xu; Yu Zhang; Xiaojing Wang; Deepak Srivastava; Sheng Ding
Journal:  Cell Rep       Date:  2014-02-20       Impact factor: 9.423

6.  Small molecules facilitate the reprogramming of mouse fibroblasts into pancreatic lineages.

Authors:  Ke Li; Saiyong Zhu; Holger A Russ; Shaohua Xu; Tao Xu; Yu Zhang; Tianhua Ma; Matthias Hebrok; Sheng Ding
Journal:  Cell Stem Cell       Date:  2014-02-06       Impact factor: 24.633

Review 7.  Chromatin dynamics during cellular reprogramming.

Authors:  Effie Apostolou; Konrad Hochedlinger
Journal:  Nature       Date:  2013-10-24       Impact factor: 49.962

8.  Deterministic direct reprogramming of somatic cells to pluripotency.

Authors:  Yoach Rais; Asaf Zviran; Shay Geula; Ohad Gafni; Elad Chomsky; Sergey Viukov; Abed AlFatah Mansour; Inbal Caspi; Vladislav Krupalnik; Mirie Zerbib; Itay Maza; Nofar Mor; Dror Baran; Leehee Weinberger; Diego A Jaitin; David Lara-Astiaso; Ronnie Blecher-Gonen; Zohar Shipony; Zohar Mukamel; Tzachi Hagai; Shlomit Gilad; Daniela Amann-Zalcenstein; Amos Tanay; Ido Amit; Noa Novershtern; Jacob H Hanna
Journal:  Nature       Date:  2013-09-18       Impact factor: 49.962

Review 9.  Toward directed reprogramming through exogenous factors.

Authors:  Changsheng Lin; Chen Yu; Sheng Ding
Journal:  Curr Opin Genet Dev       Date:  2013-08-08       Impact factor: 5.578

10.  Mouse liver repopulation with hepatocytes generated from human fibroblasts.

Authors:  Saiyong Zhu; Milad Rezvani; Jack Harbell; Aras N Mattis; Alan R Wolfe; Leslie Z Benet; Holger Willenbring; Sheng Ding
Journal:  Nature       Date:  2014-02-23       Impact factor: 49.962
View more
  21 in total

1.  Integrated Biophysical and Biochemical Signals Augment Megakaryopoiesis and Thrombopoiesis in a Three-Dimensional Rotary Culture System.

Authors:  Yiqing Yang; CuiCui Liu; Xiaohua Lei; Hongtao Wang; Pei Su; Yongxin Ru; Xinhua Ruan; Enkui Duan; Sizhou Feng; Mingzhe Han; Yuanfu Xu; Lihong Shi; Erlie Jiang; Jiaxi Zhou
Journal:  Stem Cells Transl Med       Date:  2015-12-23       Impact factor: 6.940

Review 2.  Transcription factor-mediated reprogramming: epigenetics and therapeutic potential.

Authors:  Jaber Firas; Xiaodong Liu; Sue Mei Lim; Jose M Polo
Journal:  Immunol Cell Biol       Date:  2015-02-03       Impact factor: 5.126

Review 3.  Common stemness regulators of embryonic and cancer stem cells.

Authors:  Christiana Hadjimichael; Konstantina Chanoumidou; Natalia Papadopoulou; Panagiota Arampatzi; Joseph Papamatheakis; Androniki Kretsovali
Journal:  World J Stem Cells       Date:  2015-10-26       Impact factor: 5.326

Review 4.  Looking to the future following 10 years of induced pluripotent stem cell technologies.

Authors:  Mo Li; Juan Carlos Izpisua Belmonte
Journal:  Nat Protoc       Date:  2016-08-04       Impact factor: 13.491

Review 5.  Critical roles of protein methyltransferases and demethylases in the regulation of embryonic stem cell fate.

Authors:  Theodore Vougiouklakis; Yusuke Nakamura; Vassiliki Saloura
Journal:  Epigenetics       Date:  2018-01-16       Impact factor: 4.528

Review 6.  Diversity among POU transcription factors in chromatin recognition and cell fate reprogramming.

Authors:  Vikas Malik; Dennis Zimmer; Ralf Jauch
Journal:  Cell Mol Life Sci       Date:  2018-01-15       Impact factor: 9.261

7.  Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo.

Authors:  Sophie Dal-Pra; Conrad P Hodgkinson; Maria Mirotsou; Imke Kirste; Victor J Dzau
Journal:  Circ Res       Date:  2017-02-16       Impact factor: 17.367

Review 8.  Application and prospects of high-throughput screening for in vitro neurogenesis.

Authors:  Shu-Yuan Zhang; Juan Zhao; Jun-Jun Ni; Hui Li; Zhen-Zhen Quan; Hong Qing
Journal:  World J Stem Cells       Date:  2022-06-26       Impact factor: 5.247

Review 9.  Induced pluripotent stem cells as a tool for comparative physiology: lessons from the thirteen-lined ground squirrel.

Authors:  Jingxing Ou; Sarah Rosa; Luke E Berchowitz; Wei Li
Journal:  J Exp Biol       Date:  2019-10-04       Impact factor: 3.312

Review 10.  Direct cell reprogramming: approaches, mechanisms and progress.

Authors:  Haofei Wang; Yuchen Yang; Jiandong Liu; Li Qian
Journal:  Nat Rev Mol Cell Biol       Date:  2021-02-22       Impact factor: 113.915
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.