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Literature DB >> 2544569

Methionine aminopeptidase gene of Escherichia coli is essential for cell growth.

Abstract

We localized the methionine aminopeptidase (map) gene on the Escherichia coli chromosome next to the rpsB gene at min 4. Genetically modified strains with the chromosomal map gene under lac promoter control grew only in the presence of the lac operon inducer isopropyl-beta-thiogalactoside. Thus, methionine aminopeptidase is essential for cell growth.

Entities: Gene Species

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Year: 1989 PMID： 2544569 PMCID： PMC210164 DOI： 10.1128/jb.171.7.4071-4072.1989

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

13 in total

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Authors: A C Chang; S N Cohen
Journal: J Bacteriol Date: 1978-06 Impact factor: 3.490

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Authors: C L Smith; G Condemine; S Y Chang; E McGary; S Chang
Journal: Nucleic Acids Res Date: 1989-01-25 Impact factor: 16.971

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Journal: J Bacteriol Date: 1985-03 Impact factor: 3.490

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Journal: Microbiol Rev Date: 1983-06

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Journal: Mol Gen Genet Date: 1981

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Authors: C Yanisch-Perron; J Vieira; J Messing
Journal: Gene Date: 1985 Impact factor: 3.688

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Authors: C G Miller; G Schwartz
Journal: J Bacteriol Date: 1978-08 Impact factor: 3.490

82 in total

1. Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases.

Authors: Qing Xiao; Feiran Zhang; Benjamin A Nacev; Jun O Liu; Dehua Pei
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2. Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents.

Authors: Travis R Helgren; Congling Chen; Phumvadee Wangtrakuldee; Thomas E Edwards; Bart L Staker; Jan Abendroth; Banumathi Sankaran; Nicole A Housley; Peter J Myler; Jonathon P Audia; James R Horn; Timothy J Hagen
Journal: Bioorg Med Chem Date: 2016-11-10 Impact factor: 3.641

3. Omics Assisted N-terminal Proteoform and Protein Expression Profiling On Methionine Aminopeptidase 1 (MetAP1) Deletion.

Authors: Veronique Jonckheere; Daria Fijałkowska; Petra Van Damme
Journal: Mol Cell Proteomics Date: 2018-01-09 Impact factor: 5.911

4. Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics.

Authors: Mona D Lee; Yuhong She; Michael J Soskis; Christopher P Borella; Jeffrey R Gardner; Paula A Hayes; Benzon M Dy; Mark L Heaney; Mark R Philips; William G Bornmann; Francis M Sirotnak; David A Scheinberg
Journal: J Clin Invest Date: 2004-10 Impact factor: 14.808

5. Characterization of the active site and insight into the binding mode of the anti-angiogenesis agent fumagillin to the manganese(II)-loaded methionyl aminopeptidase from Escherichia coli.

Authors: Ventris M D'souza; Robert S Brown; Brian Bennett; Richard C Holz
Journal: J Biol Inorg Chem Date: 2004-12-01 Impact factor: 3.358

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Authors: T Meinnel; S Blanquet
Journal: J Bacteriol Date: 1994-12 Impact factor: 3.490

7. The identification of inhibitory compounds of Rickettsia prowazekii methionine aminopeptidase for antibacterial applications.

Authors: Travis R Helgren; Elif S Seven; Congling Chen; Thomas E Edwards; Bart L Staker; Jan Abendroth; Peter J Myler; James R Horn; Timothy J Hagen
Journal: Bioorg Med Chem Lett Date: 2018-03-15 Impact factor: 2.823