Literature DB >> 25445055

The absence of task-related increases in BOLD signal does not equate to absence of task-related brain activation.

Jiansong Xu1, Vince D Calhoun2, Marc N Potenza3.   

Abstract

Most fMRI studies employ general-linear-model-based analyses (GLM-BA) of BOLD signal changes to identify regions that are active (or not) during specific cognitive processes. However, alternate analytic approaches (like independent component analysis) may identify more complex patterns of activation, including in regions not implicated in GLM-BA of the same data. In our opinion, fMRI findings revealed by a GLM-BA cannot exclude any brain regions from contributing to specific cognitive processes.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Balanced excitation and inhibition; Functional heterogeneity; General linear model; Spatial independent component analysis

Mesh:

Substances:

Year:  2014        PMID: 25445055      PMCID: PMC4470484          DOI: 10.1016/j.jneumeth.2014.11.002

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN: 0165-0270            Impact factor:   2.390


  21 in total

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7.  Task-related concurrent but opposite modulations of overlapping functional networks as revealed by spatial ICA.

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  10 in total

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4.  Age-related striatal BOLD changes without changes in behavioral loss aversion.

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Review 7.  Large-scale functional network overlap is a general property of brain functional organization: Reconciling inconsistent fMRI findings from general-linear-model-based analyses.

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8.  Olfactory training induces changes in regional functional connectivity in patients with long-term smell loss.

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10.  Altered functional network activities for behavioral adjustments and Bayesian learning in young men with Internet gaming disorder.

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  10 in total

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