Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine.

Literature DB >> 25412661

Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine.

Tingting Zhu¹, Ian A Roundtree², Ping Wang¹, Xiao Wang³, Li Wang¹, Chang Sun¹, Yuan Tian¹, Jie Li¹, Chuan He³, Yanhui Xu¹.

Abstract

Entities: Chemical Gene

Mesh：

Substances：

Year: 2014 PMID： 25412661 PMCID： PMC4260350 DOI： 10.1038/cr.2014.152

Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617

× No keyword cloud information.

15 in total

1. Alternatively expressed domains of AU-rich element RNA-binding protein 1 (AUF1) regulate RNA-binding affinity, RNA-induced protein oligomerization, and the local conformation of bound RNA ligands.

Authors: Beth E Zucconi; Jeff D Ballin; Brandy Y Brewer; Christina R Ross; Jun Huang; Eric A Toth; Gerald M Wilson
Journal: J Biol Chem Date: 2010-10-06 Impact factor: 5.157

2. RNA-methylation-dependent RNA processing controls the speed of the circadian clock.

Authors: Jean-Michel Fustin; Masao Doi; Yoshiaki Yamaguchi; Hayashi Hida; Shinichi Nishimura; Minoru Yoshida; Takayuki Isagawa; Masaki Suimye Morioka; Hideaki Kakeya; Ichiro Manabe; Hitoshi Okamura
Journal: Cell Date: 2013-11-07 Impact factor: 41.582

3. N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells.

Authors: Yang Wang; Yue Li; Julia I Toth; Matthew D Petroski; Zhaolei Zhang; Jing Crystal Zhao
Journal: Nat Cell Biol Date: 2014-01-07 Impact factor: 28.824

4. Identification of novel Runx1 (AML1) translocation partner genes SH3D19, YTHDf2, and ZNF687 in acute myeloid leukemia.

Authors: TuDung T Nguyen; Lisa N Ma; Marilyn L Slovak; Charles D Bangs; Athena M Cherry; Daniel A Arber
Journal: Genes Chromosomes Cancer Date: 2006-10 Impact factor: 5.006

5. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.

Authors: Guanqun Zheng; John Arne Dahl; Yamei Niu; Peter Fedorcsak; Chun-Min Huang; Charles J Li; Cathrine B Vågbø; Yue Shi; Wen-Ling Wang; Shu-Hui Song; Zhike Lu; Ralph P G Bosmans; Qing Dai; Ya-Juan Hao; Xin Yang; Wen-Ming Zhao; Wei-Min Tong; Xiu-Jie Wang; Florian Bogdan; Kari Furu; Ye Fu; Guifang Jia; Xu Zhao; Jun Liu; Hans E Krokan; Arne Klungland; Yun-Gui Yang; Chuan He
Journal: Mol Cell Date: 2012-11-21 Impact factor: 17.970

6. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.

Authors: Guifang Jia; Ye Fu; Xu Zhao; Qing Dai; Guanqun Zheng; Ying Yang; Chengqi Yi; Tomas Lindahl; Tao Pan; Yun-Gui Yang; Chuan He
Journal: Nat Chem Biol Date: 2011-10-16 Impact factor: 15.040

7. Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase.

Authors: Xiao-Li Ping; Bao-Fa Sun; Lu Wang; Wen Xiao; Xin Yang; Wen-Jia Wang; Samir Adhikari; Yue Shi; Ying Lv; Yu-Sheng Chen; Xu Zhao; Ang Li; Ying Yang; Ujwal Dahal; Xiao-Min Lou; Xi Liu; Jun Huang; Wei-Ping Yuan; Xiao-Fan Zhu; Tao Cheng; Yong-Liang Zhao; Xinquan Wang; Jannie M Rendtlew Danielsen; Feng Liu; Yun-Gui Yang
Journal: Cell Res Date: 2014-01-10 Impact factor: 25.617

8. High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis.

Authors: Schraga Schwartz; Sudeep D Agarwala; Maxwell R Mumbach; Marko Jovanovic; Philipp Mertins; Alexander Shishkin; Yuval Tabach; Tarjei S Mikkelsen; Rahul Satija; Gary Ruvkun; Steven A Carr; Eric S Lander; Gerald R Fink; Aviv Regev
Journal: Cell Date: 2013-11-21 Impact factor: 41.582

9. N6-methyladenosine-dependent regulation of messenger RNA stability.

Authors: Xiao Wang; Zhike Lu; Adrian Gomez; Gary C Hon; Yanan Yue; Dali Han; Ye Fu; Marc Parisien; Qing Dai; Guifang Jia; Bing Ren; Tao Pan; Chuan He
Journal: Nature Date: 2013-11-27 Impact factor: 49.962

10. Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq.

Authors: Dan Dominissini; Sharon Moshitch-Moshkovitz; Schraga Schwartz; Mali Salmon-Divon; Lior Ungar; Sivan Osenberg; Karen Cesarkas; Jasmine Jacob-Hirsch; Ninette Amariglio; Martin Kupiec; Rotem Sorek; Gideon Rechavi
Journal: Nature Date: 2012-04-29 Impact factor: 49.962

116 in total

Review 1. The regulation and functions of the nuclear RNA exosome complex.

Authors: Cornelia Kilchert; Sina Wittmann; Lidia Vasiljeva
Journal: Nat Rev Mol Cell Biol Date: 2016-01-04 Impact factor: 94.444

Review 2. RNA epigenetics--chemical messages for posttranscriptional gene regulation.

Authors: Ian A Roundtree; Chuan He
Journal: Curr Opin Chem Biol Date: 2015-11-26 Impact factor: 8.822

3. Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.

Authors: Chao Xu; Ke Liu; Hazem Ahmed; Peter Loppnau; Matthieu Schapira; Jinrong Min
Journal: J Biol Chem Date: 2015-08-28 Impact factor: 5.157

4. Identification of YTH Domain-Containing Proteins as the Readers for N1-Methyladenosine in RNA.

Authors: Xiaoxia Dai; Tianlu Wang; Gwendolyn Gonzalez; Yinsheng Wang
Journal: Anal Chem Date: 2018-05-25 Impact factor: 6.986

Review 5. Small changes, big implications: The impact of m⁶A RNA methylation on gene expression in pluripotency and development.

Authors: Adam M Heck; Carol J Wilusz
Journal: Biochim Biophys Acta Gene Regul Mech Date: 2019-07-17 Impact factor: 4.490

Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine.

1. Alternatively expressed domains of AU-rich element RNA-binding protein 1 (AUF1) regulate RNA-binding affinity, RNA-induced protein oligomerization, and the local conformation of bound RNA ligands.

2. RNA-methylation-dependent RNA processing controls the speed of the circadian clock.

3. N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells.

4. Identification of novel Runx1 (AML1) translocation partner genes SH3D19, YTHDf2, and ZNF687 in acute myeloid leukemia.

5. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.

6. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.

7. Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase.

8. High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis.

9. N6-methyladenosine-dependent regulation of messenger RNA stability.

10. Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq.

Review 1. The regulation and functions of the nuclear RNA exosome complex.

Review 2. RNA epigenetics--chemical messages for posttranscriptional gene regulation.

3. Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.

4. Identification of YTH Domain-Containing Proteins as the Readers for N1-Methyladenosine in RNA.

Review 5. Small changes, big implications: The impact of m⁶A RNA methylation on gene expression in pluripotency and development.

Review 6. The Epitranscriptome in Translation Regulation.

Review 7. Detecting and interpreting DNA methylation marks.

8. m⁶A modulates haematopoietic stem and progenitor cell specification.

Review 9. How RNA-Binding Proteins Interact with RNA: Molecules and Mechanisms.

Review 10. m⁶A RNA Methylation Controls Neural Development and Is Involved in Human Diseases.

Review 1. The regulation and functions of the nuclear RNA exosome complex.

Review 2. RNA epigenetics--chemical messages for posttranscriptional gene regulation.

Review 5. Small changes, big implications: The impact of m6A RNA methylation on gene expression in pluripotency and development.

Review 6. The Epitranscriptome in Translation Regulation.

Review 7. Detecting and interpreting DNA methylation marks.

Review 9. How RNA-Binding Proteins Interact with RNA: Molecules and Mechanisms.

Review 10. m6A RNA Methylation Controls Neural Development and Is Involved in Human Diseases.

Review 5. Small changes, big implications: The impact of m⁶A RNA methylation on gene expression in pluripotency and development.

Review 10. m⁶A RNA Methylation Controls Neural Development and Is Involved in Human Diseases.