Literature DB >> 25315039

Design strategies for bioorthogonal smart probes.

Peyton Shieh1, Carolyn R Bertozzi.   

Abstract

Bioorthogonal chemistry has enabled the selective labeling and detection of biomolecules in living systems. Bioorthogonal smart probes, which become fluorescent or deliver imaging or therapeutic agents upon reaction, allow for the visualization of biomolecules or targeted delivery even in the presence of excess unreacted probe. This review discusses the strategies used in the development of bioorthogonal smart probes and highlights the potential of these probes to further our understanding of biology.

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Year:  2014        PMID： 25315039      PMCID： PMC4259128          DOI： 10.1039/c4ob01632g

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  115 in total

1.  Mechanistic investigation of the staudinger ligation.

Authors:  Fiona L Lin; Helen M Hoyt; Herman van Halbeek; Robert G Bergman; Carolyn R Bertozzi
Journal:  J Am Chem Soc       Date:  2005-03-02       Impact factor: 15.419

2.  A new drug-release method using the Staudinger ligation.

Authors:  Michel Azoulay; Gérald Tuffin; Wafa Sallem; Jean-Claude Florent
Journal:  Bioorg Med Chem Lett       Date:  2006-04-18       Impact factor: 2.823

3.  A FRET-based fluorogenic phosphine for live-cell imaging with the Staudinger ligation.

Authors:  Matthew J Hangauer; Carolyn R Bertozzi
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

4.  In situ synthesis of alkenyl tetrazines for highly fluorogenic bioorthogonal live-cell imaging probes.

Authors:  Haoxing Wu; Jun Yang; Jolita Šečkutė; Neal K Devaraj
Journal:  Angew Chem Int Ed Engl       Date:  2014-04-24       Impact factor: 15.336

Review 5.  Finding the right (bioorthogonal) chemistry.

Authors:  David M Patterson; Lidia A Nazarova; Jennifer A Prescher
Journal:  ACS Chem Biol       Date:  2014-01-30       Impact factor: 5.100

6.  New generation of bioorthogonally applicable fluorogenic dyes with visible excitations and large Stokes shifts.

Authors:  András Herner; Gemma Estrada Girona; Ivana Nikić; Mihály Kállay; Edward A Lemke; Péter Kele
Journal:  Bioconjug Chem       Date:  2014-06-23       Impact factor: 4.774

7.  A fluorogenic probe for the catalyst-free detection of azide-tagged molecules.

Authors:  Frédéric Friscourt; Christoph J Fahrni; Geert-Jan Boons
Journal:  J Am Chem Soc       Date:  2012-11-02       Impact factor: 15.419

8.  "Click-fluors": modular fluorescent saccharide sensors based on a 1,2,3-triazole ring.

Authors:  David K Scrafton; James E Taylor; Mary F Mahon; John S Fossey; Tony D James
Journal:  J Org Chem       Date:  2008-03-13       Impact factor: 4.354

9.  Fluorogenic, two-photon-triggered photoclick chemistry in live mammalian cells.

Authors:  Zhipeng Yu; Tymish Y Ohulchanskyy; Peng An; Paras N Prasad; Qing Lin
Journal:  J Am Chem Soc       Date:  2013-10-31       Impact factor: 15.419

10.  Genetic Encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions.

Authors:  Kathrin Lang; Lloyd Davis; Stephen Wallace; Mohan Mahesh; Daniel J Cox; Melissa L Blackman; Joseph M Fox; Jason W Chin
Journal:  J Am Chem Soc       Date:  2012-06-13       Impact factor: 15.419
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  48 in total

1.  Fitness Factors for Bioorthogonal Chemical Probes.

Authors:  Yulin Tian; Qing Lin
Journal:  ACS Chem Biol       Date:  2019-12-05       Impact factor: 5.100

2.  Fluorogenic diazaborine formation of semicarbazide with designed coumarin derivatives.

Authors:  Samantha Cambray; Anupam Bandyopadhyay; Jianmin Gao
Journal:  Chem Commun (Camb)       Date:  2017-11-21       Impact factor: 6.222

3.  Sequential Photochemistry of Dibenzo[a,e]dicyclopropa[c,g][8]annulene-1,6-dione: Selective Formation of Didehydrodibenzo[a,e][8]annulenes with Ultrafast SPAAC Reactivity.

Authors:  Dewey A Sutton; Vladimir V Popik
Journal:  J Org Chem       Date:  2016-09-29       Impact factor: 4.354

4.  Click and Fluoresce: A Bioorthogonally Activated Smart Probe for Wash-Free Fluorescent Labeling of Biomolecules.

Authors:  Xingyue Ji; Kaili Ji; Vayou Chittavong; Robert E Aghoghovbia; Mengyuan Zhu; Binghe Wang
Journal:  J Org Chem       Date:  2017-01-23       Impact factor: 4.354

5.  Engineering of a Red Fluorogenic Protein/Merocyanine Complex for Live-Cell Imaging.

Authors:  Elizabeth M Santos; Tetyana Berbasova; Wenjing Wang; Rahele Esmatpour Salmani; Wei Sheng; Chrysoula Vasileiou; James H Geiger; Babak Borhan
Journal:  Chembiochem       Date:  2019-11-13       Impact factor: 3.164

Review 6.  A molecular engineering toolbox for the structural biologist.

Authors:  Galia T Debelouchina; Tom W Muir
Journal:  Q Rev Biophys       Date:  2017-01       Impact factor: 5.318

7.  Targeting Reactive Carbonyls for Identifying Natural Products and Their Biosynthetic Origins.

Authors:  Tucker Maxson; Jonathan I Tietz; Graham A Hudson; Xiao Rui Guo; Hua-Chia Tai; Douglas A Mitchell
Journal:  J Am Chem Soc       Date:  2016-11-14       Impact factor: 15.419

8.  A fluorogenic screening platform enables directed evolution of an alkyne biosynthetic tool.

Authors:  Xuejun Zhu; Peyton Shieh; Michael Su; Carolyn R Bertozzi; Wenjun Zhang
Journal:  Chem Commun (Camb)       Date:  2016-08-25       Impact factor: 6.222

9.  A genetically encoded cyclobutene probe for labelling of live cells.

Authors:  K Liu; B Enns; B Evans; N Wang; X Shang; W Sittiwong; P H Dussault; J Guo
Journal:  Chem Commun (Camb)       Date:  2017-09-21       Impact factor: 6.222

Review 10.  Covalent labeling of nucleic acids.

Authors:  Nils Klöcker; Florian P Weissenboeck; Andrea Rentmeister
Journal:  Chem Soc Rev       Date:  2020-10-21       Impact factor: 54.564
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