| Literature DB >> 16621529 |
Michel Azoulay1, Gérald Tuffin, Wafa Sallem, Jean-Claude Florent.
Abstract
Many drugs induce severe side-effects caused by their lack of selectivity. One way to overcome this problem is to design a specific system which releases a free drug in a controlled manner. Herein we describe a new way to liberate a drug from a prodrug using the Staudinger ligation as the trigger.Mesh：
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Year: 2006 PMID： 16621529 DOI： 10.1016/j.bmcl.2006.03.073
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823