Literature DB >> 25163758

CT-guided biopsy of pulmonary nodules: is pulmonary hemorrhage a complication or an advantage?

Massimo De Filippo1, Luca Saba, Mario Silva, Raffaella Zagaria, Giorgio Concari, Rita Nizzoli, Cecilia Bozzetti, Marcello Tiseo, Andrea Ardizzoni, Stefano Lipia, Ilaria Paladini, Luca Macarini, Giampaolo Carrafiello, Luca Brunese, Antonio Rotondo, Cristina Rossi.   

Abstract

PURPOSE: We aimed to assess the correlation between pulmonary hemorrhage and pneumothorax in computed tomography (CT)-guided transthoracic fine needle aspiration (TTFNA), particularly its possible value as protection against the development of pneumotorax.
MATERIALS AND METHODS: We reviewed the CT images of 538 patients (364 males and 174 females, mean age 70 years, range 36-90 years) who underwent CT-guided TTFNA of pulmonary nodules between January 2008 and September 2013. The following CT findings were assessed: pulmonary hemorrhage (type 1, along the needle track; type 2, perilesional; low-grade, ≤6 mm; high-grade, >6 mm), pneumothorax, distance between the target nodule and the pleural surface, and emphysema.
RESULTS: Pneumothorax occurred in 154 cases (28.6%) and pulmonary hemorrhage occurred in 144 cases (26.8%). The incidence of pneumothorax was lower in patients showing type 1 and high-grade pulmonary hemorrhage pattern. The incidence of pneumothorax in biopsies ≥30 mm from pleural surface was 26% (12/46) in cases showing this pattern, while it was 71.4% (30/42) when this pattern was not seen. Similarly, the incidence of pneumothorax in biopsies <30 mm from the pleural surface was 0% (0/28) in cases showing this hemorrhage pattern, while it was 19% (76/394) when this pattern was not seen.
CONCLUSION: Pulmonary hemorrhage during TTFNA is a frequent event that protects against pneumothorax. A bleeding greater than 6 mm along the needle track is associated with lower incidence of pneumothorax, especially in biopsies deeper than 3 cm.

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Year:  2014        PMID: 25163758      PMCID: PMC4463325          DOI: 10.5152/dir.2014.14019

Source DB:  PubMed          Journal:  Diagn Interv Radiol        ISSN: 1305-3825            Impact factor:   2.630


  21 in total

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3.  Predictive factors of diagnostic accuracy of CT-guided transthoracic fine-needle aspiration for solid noncalcified, subsolid and mixed pulmonary nodules.

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9.  Percutaneous transthoracic needle aspiration biopsy: a comprehensive review of its current role in the diagnosis and treatment of lung tumors.

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3.  Extra-pleuric coaxial system for CT-guided percutaneous fine-needle aspiration biopsy (FNAB) of small (≤20 mm) lung nodules: a novel technique using multiplanar reconstruction (MPR) images.

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4.  Feasibility and accuracy of CT-guided percutaneous needle biopsy of cavitary pulmonary lesions.

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6.  Effect of Needle-Tract Bleeding on Pneumothorax and Chest Tube Placement Following CT Guided Core Needle Lung Biopsy.

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7.  Influencing factors of pneumothorax and parenchymal haemorrhage after CT-guided transthoracic needle biopsy: single-institution experience.

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8.  CT-guided blood tattoo for thoracoscopic excision of lung lesions in pediatric patients.

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Review 9.  Computed Tomography-guided Lung Biopsy: A Review of Techniques for Reducing the Incidence of Complications.

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10.  Pneumothorax rates in CT-Guided lung biopsies: a comprehensive systematic review and meta-analysis of risk factors.

Authors:  Ya Ruth Huo; Michael Vinchill Chan; Al-Rahim Habib; Isaac Lui; Lloyd Ridley
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  10 in total

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