Literature DB >> 27132130

CT-guided fine-needle ago-biopsy of pulmonary nodules: predictive factors for diagnosis and pneumothorax occurrence.

Marco Chiappetta1, Francesco Rosella2, Valentina Dall'armi3, Leda Marina Pomes4, Leonardo Petracca Ciavarella4, Dania Nachira4, Tommaso Pirronti2, Stefano Margaritora4, Pierluigi Granone4.   

Abstract

OBJECTIVE: To evaluate variables that could predict diagnosis during CT-guided fine-needle aspiration.
METHODS: Data from 249 patients who underwent FNAB from January 2010 to December 2012 were analyzed in a retrospective observational study.
RESULTS: Mean age was 66.7 ± 11.5 years, male/female ratio 158/91 (63 vs. 37 %). The nodules were in right lung in 123 patients (49 %), in left lung in 126 patients (51 %), the upper, lower and middle lobe localizations were, respectively in 122 (49 %), 100 (40 %) and 17 (6 %) patients. Mean nodule-chest wall distance was 63.89 ± 21.38 mm. The tumor location, the needle diameter, the presence of necrosis or cavitation, the node-chest wall distance and the number of passages were not related to the diagnostic outcome (p = NS). The nodule diameter was predictive of diagnosis. Odds ratio for a 10-30 mm tumor was 2.51 (95 % OR: 1.24-5.08, p value = 0.011), the odds ratio for a 30-50 mm tumor was 2.39 (95 % OR: 1.22-4.69, p value = 0.011), and the odds ratio for a tumor larger than 50 mm was 4.44 (95 % OR: 1.89-10.44, p value = 0.001). Post-procedure pneumothorax occurred in 62 cases (25 %). The determinant factors for pneumothorax occurrence were emphysema, odds ratio 6.87 (95 % CI 1.07-44.10, p value = 0.04), and the number of pleural passages, odds ratio of 5.47 (95 % OR: 1.92-15.58), 7.44 (95 % OR: 2.58-21.5), 6.13 (95 % OR: 2.07-18.11) p value = 0.001 for one, two, three or more of three passages, respectively.
CONCLUSIONS: In our experience, nodule size is the most important diagnostic factor during fine-needle aspiration, while the number of passages and the presence of emphysema constitute risk factors for pneumothorax occurrence.

Entities:  

Keywords:  FNAB; Lung biopsy; Lung cancer; Pneumothorax

Mesh:

Year:  2016        PMID: 27132130     DOI: 10.1007/s11547-016-0639-0

Source DB:  PubMed          Journal:  Radiol Med        ISSN: 0033-8362            Impact factor:   3.469


  19 in total

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2.  Predictive factors of diagnostic accuracy of CT-guided transthoracic fine-needle aspiration for solid noncalcified, subsolid and mixed pulmonary nodules.

Authors:  Massimo De Filippo; Luca Saba; Giorgio Concari; Rita Nizzoli; Lilia Ferrari; Marcello Tiseo; Andrea Ardizzoni; Nicola Sverzellati; Ilaria Paladini; Chiara Ganazzoli; Luca Maria Sconfienza; Giampaolo Carrafiello; Luca Brunese; Eugenio Annibale Genovese; Luca Ampollini; Paolo Carbognani; Michele Rusca; Maurizio Zompatori; Cristina Rossi
Journal:  Radiol Med       Date:  2013-07-25       Impact factor: 3.469

3.  Risk factor analysis of pulmonary hemorrhage complicating CT-guided lung biopsy in coaxial and non-coaxial core biopsy techniques in 650 patients.

Authors:  Nour-Eldin A Nour-Eldin; Mohammed Alsubhi; Nagy N Naguib; Thomas Lehnert; Ahmed Emam; Martin Beeres; Boris Bodelle; Karen Koitka; Thomas J Vogl; Volkmar Jacobi
Journal:  Eur J Radiol       Date:  2014-07-05       Impact factor: 3.528

4.  Percutaneous transthoracic needle biopsy of small (≤ 1 cm) lung nodules under C-arm cone-beam CT virtual navigation guidance.

Authors:  Ji Yung Choo; Chang Min Park; Nyoung Keun Lee; Sang Min Lee; Hyun-Ju Lee; Jin Mo Goo
Journal:  Eur Radiol       Date:  2012-09-14       Impact factor: 5.315

5.  Percutaneous CT-guided multisampling core needle biopsy of thoracic lesions.

Authors:  Pierre Loubeyre; Michele Copercini; Pierre-Yves Dietrich
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6.  CT-guided core biopsy of malignant lung lesions: how many needle passes are needed?

Authors:  Chaehun Lim; Kyo Young Lee; Young Kyoon Kim; Jeong Min Ko; Dae Hee Han
Journal:  J Med Imaging Radiat Oncol       Date:  2013-04-01       Impact factor: 1.735

7.  Computed tomography-guided needle aspiration and biopsy of pulmonary lesions: a single-center experience in 1000 patients.

Authors:  Loukia S Poulou; Paraskevi Tsagouli; Panayiotis D Ziakas; Dimitra Politi; Rodoula Trigidou; Loukas Thanos
Journal:  Acta Radiol       Date:  2013-04-30       Impact factor: 1.990

8.  C-arm cone-beam CT-guided percutaneous transthoracic needle biopsy of small (≤ 20 mm) lung nodules: diagnostic accuracy and complications in 161 patients.

Authors:  Jin Woo Choi; Chang Min Park; Jin Mo Goo; Yang-Kyun Park; Wonmo Sung; Hyun-Ju Lee; Sang Min Lee; Ji Young Ko; Mi-Suk Shim
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9.  Suitability of computed tomography-guided biopsy specimens for subtyping and genotyping of non-small-cell lung cancer.

Authors:  Shih-Hsin Hsiao; Chi-Li Chung; Chi-Ming Lee; Wei-Yu Chen; Yu-Ting Chou; Zhung-Han Wu; Yi-Chie Chen; Sey-En Lin
Journal:  Clin Lung Cancer       Date:  2013-07-25       Impact factor: 4.785

10.  CT-guided biopsy of pulmonary nodules: is pulmonary hemorrhage a complication or an advantage?

Authors:  Massimo De Filippo; Luca Saba; Mario Silva; Raffaella Zagaria; Giorgio Concari; Rita Nizzoli; Cecilia Bozzetti; Marcello Tiseo; Andrea Ardizzoni; Stefano Lipia; Ilaria Paladini; Luca Macarini; Giampaolo Carrafiello; Luca Brunese; Antonio Rotondo; Cristina Rossi
Journal:  Diagn Interv Radiol       Date:  2014 Sep-Oct       Impact factor: 2.630

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  1 in total

1.  CT-guided biopsy of pulmonary nodules; predictive factors for diagnosis: Is there room for more prognostic factors?

Authors:  Gabriele Levrini; Antonia Magnani; Roberto Sghedoni; Pierpaolo Pattacini; Marco Bertolini; Andrea Botti; Valentina Iotti
Journal:  Radiol Med       Date:  2016-11-05       Impact factor: 3.469

  1 in total

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