Literature DB >> 23842769

CT-guided thoracic biopsy: evaluating diagnostic yield and complications.

Stanley E K Loh1, Donald D F Wu, Sudhakar K Venkatesh, Cheng Kang Ong, Eugene Liu, Kar Yin Seto, Anil Gopinathan, Lenny K A Tan.   

Abstract

INTRODUCTION: This study retrospectively evaluated CT-guided thoracic biopsies for diagnostic yield, accuracy and complications.
MATERIALS AND METHODS: A retrospective analysis of 384 patients (mean age 62.7 years; male/female = 251/133) who underwent 399 CT-guided thoracic biopsies were performed for evaluating diagnostic yield, accuracy and complications. Correlations between patients age, procedure factors (biopsy-needle size, number of passes, lesion-size, lesion-depth and traversed lung-length) and complications such as pneumothorax, haemothorax and haemoptysis were evaluated. A comparison between fine needle aspiration (FNA) group and core ± FNA group for diagnostic yield and complications was also performed.
RESULTS: FNA was performed in 349 patients and core ± FNA in 50 patients. The biopsy samples were adequate in 91.9% and the diagnostic accuracy for malignant lesions was 96.8% with 95.7% sensitivity and 100% specificity. Pneumothorax (detected on CT) occurred in 139 cases (34.8%) and only 12 (3.0%) required insertion of an intercostals drain. Mild haemoptysis occurred in 13 patients (3.2%) and small haemothoraces in 2 patients. Pneumothorax occurrence was significantly associated with the traversed lung-length (>3mm), lesion-size (≤33 mm) and lesion-depth (≥60mm) (P <0.05). Haemoptysis occurrence was also significantly associated with traversed lunglength (>3mm) and lesion-size (≤33 mm) (P <0.05). There was no significant difference between diagnostic yield and complication rate between FNA and core ± FNA groups.
CONCLUSION: CT-guided thoracic biopsy is a safe procedure with high diagnostic yield and low risk of significant complications. Traversed lung-length and smaller lesion size are associated with occurrence of pneumothorax and haemoptysis.

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Year:  2013        PMID: 23842769

Source DB:  PubMed          Journal:  Ann Acad Med Singapore        ISSN: 0304-4602            Impact factor:   2.473


  20 in total

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6.  CT-guided biopsy of pulmonary nodules: is pulmonary hemorrhage a complication or an advantage?

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Review 7.  Transthoracic needle biopsy of the lung.

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Journal:  J Thorac Dis       Date:  2015-12       Impact factor: 2.895

8.  Risk factors for hemoptysis complicating 17-18 gauge CT-guided transthoracic needle core biopsy: multivariate analysis of 249 procedures.

Authors:  Guillaume Chassagnon; Jules Gregory; Marc Al Ahmar; Pierre Magdeleinat; Paul Legmann; Joel Coste; Marie Pierre Revel
Journal:  Diagn Interv Radiol       Date:  2017 Sep-Oct       Impact factor: 2.630

9.  Predictors of technical success and rate of complications of image-guided percutaneous transthoracic lung needle biopsy of pulmonary tumors.

Authors:  Stephan Otto; Birger Mensel; Nele Friedrich; Sophia Schäfer; Christoph Mahlke; Wolfram von Bernstorff; Karen Bock; Norbert Hosten; Jens-Peter Kühn
Journal:  PLoS One       Date:  2015-04-09       Impact factor: 3.240

10.  Impact of immediate evaluation of touch imprint cytology from computed tomography guided core needle biopsies of mass lesions: Single institution experience.

Authors:  Mana Moghadamfalahi; Mirna Podoll; Amy B Frey; Houda Alatassi
Journal:  Cytojournal       Date:  2014-06-12       Impact factor: 2.091

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