Literature DB >> 25161940

Anatomical characterization of central, apical and minimal corneal thickness.

Federico Saenz-Frances1, Martha Cecilia Bermúdez-Vallecilla1, Lara Borrego-Sanz1, Luis Jañez2, José María Martinez-de-la-Casa1, Laura Morales-Fernandez1, Enrique Santos-Bueso1, Julián Garcia-Sanchez1, Julián Garcia-Feijoo1.   

Abstract

AIM: To anatomically locate the points of minimum corneal thickness and central corneal thickness (pupil center) in relation to the corneal apex.
METHODS: Observational, cross-sectional study, 299 healthy volunteers. Thickness at the corneal apex (AT), minimum corneal thickness (MT) and corneal thickness at the pupil center (PT) were determined using the pentacam. Distances from the corneal apex to MT (MD) and PT (PD) were calculated and their quadrant position (taking the corneal apex as the reference) determined: point of minimum thickness (MC) and point of central thickness (PC) depending on the quadrant position. Two multivariate linear regression models were constructed to examine the influence of age, gender, power of the flattest and steepest corneal axes, position of the flattest axis, corneal volume (determined using the Pentacam) and PT on MD and PD. The effects of these variables on MC and PC were also determined in two multinomial regression models.
RESULTS: MT was located at a mean distance of 0.909 mm from the apex (79.4% in the inferior-temporal quadrant). PT was located at a mean distance of 0.156 mm from the apex. The linear regression model for MD indicated it was significantly influenced by corneal volume (B=-0.024; 95%CI: -0.043 to -0.004). No significant relations were identified in the linear regression model for PD or the multinomial logistic regressions for MC and PC.
CONCLUSION: MT was typically located at the inferior-temporal quadrant of the cornea and its distance to the corneal apex tended to decrease with the increment of corneal volume.

Entities:  

Keywords:  anatomy; corneal thickness; glaucoma

Year:  2014        PMID: 25161940      PMCID: PMC4137204          DOI: 10.3980/j.issn.2222-3959.2014.04.15

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN: 2222-3959            Impact factor:   1.779


  30 in total

1.  Intrasubject repeatability of corneal morphology measurements obtained with a new Scheimpflug photography-based system.

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2.  Effect of corneal morphometry on dynamic contour and Goldmann applanation tonometry.

Authors:  Federico Saenz-Frances; Luis Jañez; Lara Borrego-Sanz; Jose Maria Martinez-de-la-Casa; Maria Jerez-Fidalgo; Julian Garcia-Sánchez; Julian Garcia-Feijoo
Journal:  J Glaucoma       Date:  2013 Jun-Jul       Impact factor: 2.503

3.  Repeatability and reproducibility of central corneal thickness measurement with Pentacam, Orbscan, and ultrasound.

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4.  Caucasian emmetropic aged subjects have reduced corneal thickness values: emmetropia, CCT and age.

Authors:  Juan A Sanchis-Gimeno; Antonio Lleó-Pérez; Luis Alonso; M S Rahhal
Journal:  Int Ophthalmol       Date:  2005-09-29       Impact factor: 2.031

5.  Reduction in intraocular pressure after excimer laser photorefractive keratectomy. Correlation with pretreatment myopia.

Authors:  A Chatterjee; S Shah; D A Bessant; S A Naroo; S J Doyle
Journal:  Ophthalmology       Date:  1997-03       Impact factor: 12.079

6.  The effect of age on human corneal thickness. Statistical implications of power analysis.

Authors:  A Siu; P Herse
Journal:  Acta Ophthalmol (Copenh)       Date:  1993-02

7.  The effect of corneal thickness on applanation tonometry.

Authors:  M M Whitacre; R A Stein; K Hassanein
Journal:  Am J Ophthalmol       Date:  1993-05-15       Impact factor: 5.258

Review 8.  Sources of error with use of Goldmann-type tonometers.

Authors:  M M Whitacre; R Stein
Journal:  Surv Ophthalmol       Date:  1993 Jul-Aug       Impact factor: 6.048

9.  Ocular hypertension and central corneal thickness.

Authors:  W A Argus
Journal:  Ophthalmology       Date:  1995-12       Impact factor: 12.079

10.  The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma.

Authors:  Mae O Gordon; Julia A Beiser; James D Brandt; Dale K Heuer; Eve J Higginbotham; Chris A Johnson; John L Keltner; J Philip Miller; Richard K Parrish; M Roy Wilson; Michael A Kass
Journal:  Arch Ophthalmol       Date:  2002-06
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  1 in total

1.  Corneal Thickness Profile and Associations in Chinese Children Aged 7 to 15 Years Old.

Authors:  Yingyan Ma; Xiaofeng Zhu; Xiangui He; Lina Lu; Jianfeng Zhu; Haidong Zou
Journal:  PLoS One       Date:  2016-01-11       Impact factor: 3.240

  1 in total

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