B C Craven1, C Balioussis2, S L Hitzig3, C Moore4, M C Verrier5, L M Giangregorio6, M R Popovic7. 1. 1] Toronto Rehabilitation Institute - University Health Network, Toronto, Ontario, Canada [2] Department of Medicine and Health Policy Management and Evaluation, University of Toronto, Toronto, Ontario, Canada. 2. Toronto Rehabilitation Institute - University Health Network, Toronto, Ontario, Canada. 3. 1] Toronto Rehabilitation Institute - University Health Network, Toronto, Ontario, Canada [2] Faculty of Medicine, Institute for Life Course and Aging, University of Toronto, Toronto, Ontario, Canada. 4. 1] Toronto Rehabilitation Institute - University Health Network, Toronto, Ontario, Canada [2] University of Waterloo, Waterloo, Ontario, Canada. 5. 1] Toronto Rehabilitation Institute - University Health Network, Toronto, Ontario, Canada [2] Department of Physical Therapy, University of Toronto, Toronto, Ontario, Canada. 6. 1] Toronto Rehabilitation Institute - University Health Network, Toronto, Ontario, Canada [2] Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada. 7. 1] Toronto Rehabilitation Institute - University Health Network, Toronto, Ontario, Canada [2] Rehabilitation Engineering Laboratory, Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.
Abstract
STUDY DESIGN: Descriptive report. OBJECTIVES: To describe screening to recruitment (S:R) ratios and discuss their use for planning and implementing research among individuals with spinal cord injury (SCI) . SETTING: Toronto, Ontario, Canada. METHODS: We calculated S:R ratios for SCI research by study methodology and nature of the exposure/intervention for 25 studies previously conducted in a tertiary SCI rehabilitation facility. Study methodologies included ten randomized controlled trials (RCTs), nine cohort studies and six panel studies. Exposures included seven rehabilitation interventions, and three drug studies, ten telephone interviews/chart abstractions (TI/CA) and five surveys. A S:R ratio was calculated for each study methodology, and exposure type, by dividing the number of consenting individuals who underwent screening by the number of eligible recruited participants enrolled in the study. RESULTS: In terms of design, RCTs had the highest median S:R ratio (3:1), followed by cohort studies (2:1) and panel studies (2:1). In terms of intervention type, drug studies had the largest median S:R ratio (5:1), followed in descending order by rehabilitation studies (2:1), TI/CAs studies (2:1) and surveys (2:1). CONCLUSIONS: Reported S:R ratios varied substantially with study methodology and the associated study intervention exposure. Awareness of S:R ratios may assist researchers in estimating recruitment timelines, personnel needs and study budgets for a required sample size based on the planned study methodology and intended study exposure. We advocate for the routine reporting of S:R ratios to inform the success of future SCI research.
STUDY DESIGN: Descriptive report. OBJECTIVES: To describe screening to recruitment (S:R) ratios and discuss their use for planning and implementing research among individuals with spinal cord injury (SCI) . SETTING: Toronto, Ontario, Canada. METHODS: We calculated S:R ratios for SCI research by study methodology and nature of the exposure/intervention for 25 studies previously conducted in a tertiary SCI rehabilitation facility. Study methodologies included ten randomized controlled trials (RCTs), nine cohort studies and six panel studies. Exposures included seven rehabilitation interventions, and three drug studies, ten telephone interviews/chart abstractions (TI/CA) and five surveys. A S:R ratio was calculated for each study methodology, and exposure type, by dividing the number of consenting individuals who underwent screening by the number of eligible recruited participants enrolled in the study. RESULTS: In terms of design, RCTs had the highest median S:R ratio (3:1), followed by cohort studies (2:1) and panel studies (2:1). In terms of intervention type, drug studies had the largest median S:R ratio (5:1), followed in descending order by rehabilitation studies (2:1), TI/CAs studies (2:1) and surveys (2:1). CONCLUSIONS: Reported S:R ratios varied substantially with study methodology and the associated study intervention exposure. Awareness of S:R ratios may assist researchers in estimating recruitment timelines, personnel needs and study budgets for a required sample size based on the planned study methodology and intended study exposure. We advocate for the routine reporting of S:R ratios to inform the success of future SCI research.
Authors: Bastien Moineau; Andrea Brown; Louise Brisbois; Vera Zivanovic; Masae Miyatani; Naaz Kapadia; Jane T C Hsieh; Milos R Popovic Journal: J Spinal Cord Med Date: 2019-10 Impact factor: 1.985
Authors: Kevin Wu; Eric Wu; Michael DAndrea; Nandini Chitale; Melody Lim; Marek Dabrowski; Klaudia Kantor; Hanoor Rangi; Ruishan Liu; Marius Garmhausen; Navdeep Pal; Chris Harbron; Shemra Rizzo; Ryan Copping; James Zou Journal: AAPS J Date: 2022-04-21 Impact factor: 4.009
Authors: B Catharine Craven; Louise Brisbois; Chelsea Pelletier; Julia Rybkina; Ann Heesters; Mary Caroline Verrier Journal: J Spinal Cord Med Date: 2021 Impact factor: 1.985