Literature DB >> 25130695

Sequential gene silencing using wavelength-selective caged morpholino oligonucleotides.

Sayumi Yamazoe1, Qingyang Liu, Lindsey E McQuade, Alexander Deiters, James K Chen.   

Abstract

Spectrally differentiated caged morpholino oligonucleotides (cMOs) and wavelength-selective illumination have been used to sequentially inactivate organismal gene function. The efficacy of these reverse-genetic chemical probes has been demonstrated in zebrafish embryos, and these reagents have been employed to examine the mechanisms of mesoderm patterning.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  antisense agents; cage compounds; developmental biology; gene expression; oligonucleotides

Mesh：

Substances：

Year:  2014        PMID： 25130695      PMCID： PMC4206551          DOI： 10.1002/anie.201405355

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  27 in total

1.  Cyclic caged morpholinos: conformationally gated probes of embryonic gene function.

Authors:  Sayumi Yamazoe; Ilya A Shestopalov; Elayne Provost; Steven D Leach; James K Chen
Journal:  Angew Chem Int Ed Engl       Date:  2012-06-11       Impact factor: 15.336

2.  Synthesis, photophysical, photochemical, and computational studies of coumarin-labeled nicotinamide derivatives.

Authors:  Pauline Bourbon; Qian Peng; Guillermo Ferraudi; Cynthia Stauffacher; Olaf Wiest; Paul Helquist
Journal:  J Org Chem       Date:  2012-03-07       Impact factor: 4.354

Review 3.  Light-controlled tools.

Authors:  Clara Brieke; Falk Rohrbach; Alexander Gottschalk; Günter Mayer; Alexander Heckel
Journal:  Angew Chem Int Ed Engl       Date:  2012-07-24       Impact factor: 15.336

4.  Photocaged morpholino oligomers for the light-regulation of gene function in zebrafish and Xenopus embryos.

Authors:  Alexander Deiters; R Aaron Garner; Hrvoje Lusic; Jeane M Govan; Mike Dush; Nanette M Nascone-Yoder; Jeffrey A Yoder
Journal:  J Am Chem Soc       Date:  2010-11-10       Impact factor: 15.419

5.  Sequential activation and deactivation of protein function using spectrally differentiated caged phosphoamino acids.

Authors:  Brenda N Goguen; Andreas Aemissegger; Barbara Imperiali
Journal:  J Am Chem Soc       Date:  2011-06-29       Impact factor: 15.419

6.  PhotoMorphs: a novel light-activated reagent for controlling gene expression in zebrafish.

Authors:  Amber J Tomasini; Aaron D Schuler; John A Zebala; Alan N Mayer
Journal:  Genesis       Date:  2009-11       Impact factor: 2.487

7.  Two-color, two-photon uncaging of glutamate and GABA.

Authors:  Srinivas Kantevari; Masanori Matsuzaki; Yuya Kanemoto; Haruo Kasai; Graham C R Ellis-Davies
Journal:  Nat Methods       Date:  2009-12-27       Impact factor: 28.547

8.  Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs.

Authors:  Lindsay Cade; Deepak Reyon; Woong Y Hwang; Shengdar Q Tsai; Samir Patel; Cyd Khayter; J Keith Joung; Jeffry D Sander; Randall T Peterson; Jing-Ruey Joanna Yeh
Journal:  Nucleic Acids Res       Date:  2012-06-07       Impact factor: 16.971

9.  Spatiotemporal resolution of the Ntla transcriptome in axial mesoderm development.

Authors:  Ilya A Shestopalov; Cameron L W Pitt; James K Chen
Journal:  Nat Chem Biol       Date:  2012-01-29       Impact factor: 15.040

10.  Turning gene function ON and OFF using sense and antisense photo-morpholinos in zebrafish.

Authors:  Alexandra Tallafuss; Dan Gibson; Paul Morcos; Yongfu Li; Steve Seredick; Judith Eisen; Philip Washbourne
Journal:  Development       Date:  2012-05       Impact factor: 6.868
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  37 in total

1.  Pseudorotaxane formation via the slippage process with chemically cyclized oligonucleotides.

Authors:  Kazumitsu Onizuka; Tomoko Chikuni; Takuya Amemiya; Takuya Miyashita; Kyoko Onizuka; Hiroshi Abe; Fumi Nagatsugi
Journal:  Nucleic Acids Res       Date:  2017-05-19       Impact factor: 16.971

Review 2.  Optochemical Control of Biological Processes in Cells and Animals.

Authors:  Nicholas Ankenbruck; Taylor Courtney; Yuta Naro; Alexander Deiters
Journal:  Angew Chem Int Ed Engl       Date:  2018-02-01       Impact factor: 15.336

3.  Illuminating developmental biology through photochemistry.

Authors:  Lukasz Kowalik; James K Chen
Journal:  Nat Chem Biol       Date:  2017-05-17       Impact factor: 15.040

4.  Photocaged DNAzymes as a general method for sensing metal ions in living cells.

Authors:  Kevin Hwang; Peiwen Wu; Taejin Kim; Lei Lei; Shiliang Tian; Yingxiao Wang; Yi Lu
Journal:  Angew Chem Int Ed Engl       Date:  2014-10-14       Impact factor: 15.336

5.  Spacer-Mediated Control of Coumarin Uncaging for Photocaged Thymidine.

Authors:  Shengzhuang Tang; Jayme Cannon; Kelly Yang; Matthew F Krummel; James R Baker; Seok Ki Choi
Journal:  J Org Chem       Date:  2020-02-05       Impact factor: 4.354

6.  Optochemical dissection of T-box gene-dependent medial floor plate development.

Authors:  Alexander Y Payumo; Whitney J Walker; Lindsey E McQuade; Sayumi Yamazoe; James K Chen
Journal:  ACS Chem Biol       Date:  2015-03-17       Impact factor: 5.100

7.  Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.

Authors:  Roy Weinstain; Tomáš Slanina; Dnyaneshwar Kand; Petr Klán
Journal:  Chem Rev       Date:  2020-10-30       Impact factor: 60.622

Review 8.  Caged oligonucleotides for studying biological systems.

Authors:  Brittani K Ruble; Sean B Yeldell; Ivan J Dmochowski
Journal:  J Inorg Biochem       Date:  2015-03-28       Impact factor: 4.155

9.  A Thioacetal Photocage Designed for Dual Release: Application in the Quantitation of Therapeutic Release by Synchronous Reporter Decaging.

Authors:  Pamela T Wong; Shengzhuang Tang; Jayme Cannon; Jhindan Mukherjee; Danielle Isham; Kristina Gam; Michael Payne; Sean A Yanik; James R Baker; Seok Ki Choi
Journal:  Chembiochem       Date:  2016-11-30       Impact factor: 3.164

10.  Combinatorial control of gene function with wavelength-selective caged morpholinos.

Authors:  Sankha Pattanayak; Luis Angel Vázquez-Maldonado; Alexander Deiters; James K Chen
Journal:  Methods Enzymol       Date:  2019-04-25       Impact factor: 1.600
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