Azien Laqmani1, Marc Regier1, Simon Veldhoen1, Alexandra Backhaus1, Felicia Wassenberg1, Susanne Sehner2, Michael Groth1, Hans-Dieter Nagel3, Gerhard Adam1, Frank O Henes4. 1. Department of Diagnostic and Interventional Radiology, University Medical Center, Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. 2. Department of Medical Biometry and Epidemiology, University Medical Center, Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. 3. Scientific and Application-oriented Studies and Consulting in Radiology (SASCRAD), Fritz-Reuter-Weg 5f, 21244 Buchholz, Germany. 4. Department of Diagnostic and Interventional Radiology, University Medical Center, Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. Electronic address: fhenes@uke.de.
Abstract
OBJECTIVES: To determine the impact of hybrid iterative reconstruction (HIR) on image quality in 80 kV CT pulmonary angiography (CTPA) in comparison to filtered-back-projection (FBP). METHODS: Fifty patients (body weight <80 kg) with suspected pulmonary embolism (PE) underwent CTPA at 80 kV (mean CTDIvol, 2.3 mGy; effective dose, 1.2 mSv). The raw data were reconstructed using FBP and three increasing HIR levels. Two radiologists assessed image quality and image noise. Conspicuity of PE was assessed in central, segmental, and subsegmental arteries. CT attenuation of pulmonary arteries, objective image noise (OIN) and contrast-to-noise ratios (CNR) were assessed. RESULTS: With each HIR level, a significant decrease in subjective and objective image noise was achieved with a reduction of OIN up to 46% in comparison with FBP. CNR significantly increased with the application of HIR compared to FBP. Image quality was rated significantly higher at HIR reconstructions in comparison with FBP. Diagnosis of PE was feasible with each data set; however, conspicuity of central and segmental PE significantly improved with the use of HIR. CONCLUSIONS: Eighty kilovoltage CTPA with HIR provides improved image quality and conspicuity of pulmonary embolism enabling low dose CTPA protocols close to 1 mSv in patients weighing less than 80 kg.
OBJECTIVES: To determine the impact of hybrid iterative reconstruction (HIR) on image quality in 80 kV CT pulmonary angiography (CTPA) in comparison to filtered-back-projection (FBP). METHODS: Fifty patients (body weight <80 kg) with suspected pulmonary embolism (PE) underwent CTPA at 80 kV (mean CTDIvol, 2.3 mGy; effective dose, 1.2 mSv). The raw data were reconstructed using FBP and three increasing HIR levels. Two radiologists assessed image quality and image noise. Conspicuity of PE was assessed in central, segmental, and subsegmental arteries. CT attenuation of pulmonary arteries, objective image noise (OIN) and contrast-to-noise ratios (CNR) were assessed. RESULTS: With each HIR level, a significant decrease in subjective and objective image noise was achieved with a reduction of OIN up to 46% in comparison with FBP. CNR significantly increased with the application of HIR compared to FBP. Image quality was rated significantly higher at HIR reconstructions in comparison with FBP. Diagnosis of PE was feasible with each data set; however, conspicuity of central and segmental PE significantly improved with the use of HIR. CONCLUSIONS: Eighty kilovoltage CTPA with HIR provides improved image quality and conspicuity of pulmonary embolism enabling low dose CTPA protocols close to 1 mSv in patients weighing less than 80 kg.
Authors: Babs M F Hendriks; Madeleine Kok; Casper Mihl; Sebastiaan C A M Bekkers; Joachim E Wildberger; Marco Das Journal: Br J Radiol Date: 2016-01-22 Impact factor: 3.039
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Authors: Azien Laqmani; Maximillian Kurfürst; Sebastian Butscheidt; Susanne Sehner; Jakob Schmidt-Holtz; Cyrus Behzadi; Hans Dieter Nagel; Gerhard Adam; Marc Regier Journal: PLoS One Date: 2016-09-09 Impact factor: 3.240
Authors: Moritz Kaup; Tatjana Gruber-Rouh; Jan E Scholtz; Moritz H Albrecht; Andreas Bucher; Claudia Frellesen; Thomas J Vogl; Martin Beeres Journal: Acta Radiol Open Date: 2016-12-01