Literature DB >> 24994041

Buccal mucosa urethroplasty: a 10-year retrospective review of maxillofacial and urological outcomes.

J E O'Connell1, I M Cullen2, C Murphy3, H Flood2, G J Kearns3.   

Abstract

BACKGROUND: Reconstruction of a urethral stricture poses a difficult surgical problem. Anastomotic repair remains the gold standard. Strictures longer than 2 cm may require substitution urethroplasty. This is a retrospective review of all patients who underwent urethral reconstruction with an autologous free buccal mucosa graft at a Regional hospital between 1998 and 2009.
METHODS: Variables recorded included; demographics: patient gender/age; follow-up period. Urology: pre-operative diagnosis/aetiology; presenting complaint; previous urological surgery, pre-operative retrograde urethrogram, stricture length, graft size, operative time/blood loss, morbidity, complications. Maxillofacial: pre-/post-operative inter-incisal opening, patency of Stenson's parotid duct, ipsilateral parotid swelling, sensory nerve deficit.
RESULTS: A total of eight male patients were included. Mean age was 33 years. Two patients had one-stage dorsal onlay urethroplasty, and the remaining six had a two-stage BMG urethroplasty. All patients underwent a urethrogram 20 days post-operatively, which demonstrated no leak, and a good caliber grafted urethra in all cases. A flexible cystoscopy scope was accommodated in all patients 8 weeks post-operatively. Mean follow-up was 42 months. At long-term follow-up, there was no evidence of stricture formation, and all patients were voiding well. There were no long-term intra-oral complications.
CONCLUSION: This study suggests that anterior urethral strictures up to 6 cm in length may be predictably and safely managed with buccal mucosal urethroplasty. The buccal mucosa is easy to harvest, and can be used successfully in one- and two-stage grafting procedures. The rate of complications, from both a urological and maxillofacial perspective, in the group of patients studied was low.

Entities:  

Keywords:  Buccal mucosa; Free grafts; Urethral stricture; Urethroplasty

Mesh:

Year:  2014        PMID: 24994041     DOI: 10.1007/s11845-014-1165-5

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  37 in total

1.  One-stage bulbar urethroplasty: retrospective analysis of the results in 375 patients.

Authors:  Guido Barbagli; Giorgio Guazzoni; Massimo Lazzeri
Journal:  Eur Urol       Date:  2008-01-22       Impact factor: 20.096

Review 2.  What is the best technique for urethroplasty?

Authors:  Daniela E Andrich; Anthony R Mundy
Journal:  Eur Urol       Date:  2008-08-19       Impact factor: 20.096

3.  Dorsal free graft urethroplasty.

Authors:  G Barbagli; C Selli; A Tosto; E Palminteri
Journal:  J Urol       Date:  1996-01       Impact factor: 7.450

4.  Multi-institutional experience with buccal mucosa onlay urethroplasty for bulbar urethral reconstruction.

Authors:  Christopher J Kane; Gregory J Tarman; Duncan J Summerton; Craig E Buchmann; John F Ward; Keith J O'Reilly; Henry Ruiz; J Brantley Thrasher; Burk Zorn; Carolyn Smith; Allen F Morey
Journal:  J Urol       Date:  2002-03       Impact factor: 7.450

Review 5.  Urethral reconstruction using buccal mucosa or penile skin grafts: systematic review and meta-analysis.

Authors:  N Lumen; W Oosterlinck; P Hoebeke
Journal:  Urol Int       Date:  2012-08-09       Impact factor: 2.089

6.  Staged reconstruction of long segment urethral strictures in men with previous pediatric hypospadias repair.

Authors:  Joshua J Meeks; Bradley A Erickson; Chris M Gonzalez
Journal:  J Urol       Date:  2008-12-16       Impact factor: 7.450

7.  Oral complications after buccal mucosal graft harvest for urethroplasty.

Authors:  Norman Dublin; Laurence H Stewart
Journal:  BJU Int       Date:  2004-10       Impact factor: 5.588

8.  Buccal mucosal grafts for urethral reconstruction.

Authors:  A A Caldamone; L E Edstrom; M A Koyle; R Rabinowitz; W C Hulbert
Journal:  Urology       Date:  1998-05       Impact factor: 2.649

9.  Early experience with the use of buccal mucosa for substitution urethroplasty.

Authors:  S N Venn; A R Mundy
Journal:  Br J Urol       Date:  1998-05

10.  Tissue-engineered buccal mucosa urethroplasty-clinical outcomes.

Authors:  Saurabh Bhargava; Jacob M Patterson; Richard D Inman; Sheila MacNeil; Christopher R Chapple
Journal:  Eur Urol       Date:  2008-02-04       Impact factor: 20.096

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