Literature DB >> 24874216

Fundamental limits of scintillation detector timing precision.

Stephen E Derenzo1, Woon-Seng Choong, William W Moses.   

Abstract

In this paper we review the primary factors that affect the timing precision of a scintillation detector. Monte Carlo calculations were performed to explore the dependence of the timing precision on the number of photoelectrons, the scintillator decay and rise times, the depth of interaction uncertainty, the time dispersion of the optical photons (modeled as an exponential decay), the photodetector rise time and transit time jitter, the leading-edge trigger level, and electronic noise. The Monte Carlo code was used to estimate the practical limits on the timing precision for an energy deposition of 511 keV in 3 mm × 3 mm × 30 mm Lu2SiO5:Ce and LaBr3:Ce crystals. The calculated timing precisions are consistent with the best experimental literature values. We then calculated the timing precision for 820 cases that sampled scintillator rise times from 0 to 1.0 ns, photon dispersion times from 0 to 0.2 ns, photodetector time jitters from 0 to 0.5 ns fwhm, and A from 10 to 10,000 photoelectrons per ns decay time. Since the timing precision R was found to depend on A(-1/2) more than any other factor, we tabulated the parameter B, where R = BA(-1/2). An empirical analytical formula was found that fit the tabulated values of B with an rms deviation of 2.2% of the value of B. The theoretical lower bound of the timing precision was calculated for the example of 0.5 ns rise time, 0.1 ns photon dispersion, and 0.2 ns fwhm photodetector time jitter. The lower bound was at most 15% lower than leading-edge timing discrimination for A from 10 to 10,000 photoelectrons ns(-1). A timing precision of 8 ps fwhm should be possible for an energy deposition of 511 keV using currently available photodetectors if a theoretically possible scintillator were developed that could produce 10,000 photoelectrons ns(-1).

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Year:  2014        PMID: 24874216      PMCID: PMC4071963          DOI: 10.1088/0031-9155/59/13/3261

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  3 in total

1.  The lower bound on the timing resolution of scintillation detectors.

Authors:  Stefan Seifert; Herman T van Dam; Dennis R Schaart
Journal:  Phys Med Biol       Date:  2012-03-13       Impact factor: 3.609

2.  Depth of interaction resolution measurements for a high resolution PET detector using position sensitive avalanche photodiodes.

Authors:  Yongfeng Yang; Purushottam A Dokhale; Robert W Silverman; Kanai S Shah; Mickel A McClish; Richard Farrell; Gerald Entine; Simon R Cherry
Journal:  Phys Med Biol       Date:  2006-04-10       Impact factor: 3.609

3.  The timing resolution of scintillation-detector systems: Monte Carlo analysis.

Authors:  Woon-Seng Choong
Journal:  Phys Med Biol       Date:  2009-10-09       Impact factor: 3.609

  3 in total
  10 in total

1.  Optimizing light transport in scintillation crystals for time-of-flight PET: an experimental and optical Monte Carlo simulation study.

Authors:  Eric Berg; Emilie Roncali; Simon R Cherry
Journal:  Biomed Opt Express       Date:  2015-05-26       Impact factor: 3.732

2.  MODELING TIME DISPERSION DUE TO OPTICAL PATH LENGTH DIFFERENCES IN SCINTILLATION DETECTORS.

Authors:  W W Moses; W-S Choong; S E Derenzo
Journal:  Acta Phys Pol B Proc Suppl       Date:  2014-03-14

Review 3.  Update on novel trends in PET/CT technology and its clinical applications.

Authors:  Stephan Walrand; Michel Hesse; François Jamar
Journal:  Br J Radiol       Date:  2016-11-25       Impact factor: 3.039

4.  A Time-Walk Correction Method for PET Detectors Based on Leading Edge Discriminators.

Authors:  Junwei Du; Jeffrey P Schmall; Martin S Judenhofer; Kun Di; Yongfeng Yang; Simon R Cherry
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2017-07-13

5.  Bright and ultra-fast scintillation from a semiconductor?

Authors:  Stephen E Derenzo; Edith Bourret-Courshesne; Gregory Bizarri; Andrew Canning
Journal:  Nucl Instrum Methods Phys Res A       Date:  2016-01-01       Impact factor: 1.455

6.  Monte Carlo simulations of time-of-flight PET with double-ended readout: calibration, coincidence resolving times and statistical lower bounds.

Authors:  Stephen E Derenzo
Journal:  Phys Med Biol       Date:  2017-03-22       Impact factor: 3.609

7.  A promising new mechanism of ionizing radiation detection for positron emission tomography: modulation of optical properties.

Authors:  Li Tao; Henry M Daghighian; Craig S Levin
Journal:  Phys Med Biol       Date:  2016-10-07       Impact factor: 3.609

8.  Modelling the transport of optical photons in scintillation detectors for diagnostic and radiotherapy imaging.

Authors:  Emilie Roncali; Mohammad Amin Mosleh-Shirazi; Aldo Badano
Journal:  Phys Med Biol       Date:  2017-10-04       Impact factor: 3.609

9.  A layered single-side readout depth of interaction time-of-flight-PET detector.

Authors:  L Bläckberg; S Sajedi; G El Fakhri; H Sabet
Journal:  Phys Med Biol       Date:  2021-02-11       Impact factor: 3.609

10.  Monte Carlo calculations of PET coincidence timing: single and double-ended readout.

Authors:  Stephen E Derenzo; Woon-Seng Choong; William W Moses
Journal:  Phys Med Biol       Date:  2015-09-09       Impact factor: 3.609

  10 in total

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