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Literature DB >> 24769796

Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles.

Andrew G Cheetham¹, Yu-Chuan Ou, Pengcheng Zhang, Honggang Cui.

Abstract

We report here that the release mechanism of free camptothecin from self-assembling drug amphiphiles can be regulated by use of different linker groups. Our results highlight the significance of the linker group of drug amphiphiles on the drug release efficiency and their consequent in vitro efficacy.

Entities: Chemical

Mesh：

Substances：

Year: 2014 PMID： 24769796 PMCID： PMC4160079 DOI： 10.1039/c3cc49453e

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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