Literature DB >> 21399797

pH-Sensitive brush polymer-drug conjugates by ring-opening metathesis copolymerization.

Jiong Zou1, Goran Jafr, Efrosyni Themistou, Yoonsing Yap, Zachary A P Wintrob, Paschalis Alexandridis, Alice C Ceacareanu, Chong Cheng.   

Abstract

Representing a new category of polymer-drug conjugates, brush polymer-drug conjugates were prepared by ring-opening metathesis copolymerization. Following judicious structural design, these conjugates exhibited well-shielded drug moieties, significant water solubility, well-defined nanostructures, and acid-triggered drug release. © The Royal Society of Chemistry 2011

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Year:  2011        PMID： 21399797     DOI： 10.1039/c0cc05531j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  10 in total

1.  Poly(ethylene oxide)-block-polyphosphoester-graft-paclitaxel conjugates with acid-labile linkages as a pH-sensitive and functional nanoscopic platform for paclitaxel delivery.

Authors:  Jiong Zou; Fuwu Zhang; Shiyi Zhang; Stephanie F Pollack; Mahmoud Elsabahy; Jingwei Fan; Karen L Wooley
Journal:  Adv Healthc Mater       Date:  2013-08-30       Impact factor: 9.933

2.  Molecular design and synthesis of self-assembling camptothecin drug amphiphiles.

Authors:  Andrew G Cheetham; Yi-An Lin; Ran Lin; Honggang Cui
Journal:  Acta Pharmacol Sin       Date:  2017-03-06       Impact factor: 6.150

3.  Shape Control in Engineering of Polymeric Nanoparticles for Therapeutic Delivery.

Authors:  John-Michael Williford; Jose Luis Santos; Rishab Shyam; Hai-Quan Mao
Journal:  Biomater Sci       Date:  2015-07       Impact factor: 6.843

Review 4.  Design of polymeric nanoparticles for biomedical delivery applications.

Authors:  Mahmoud Elsabahy; Karen L Wooley
Journal:  Chem Soc Rev       Date:  2012-02-14       Impact factor: 54.564

5.  Scalable Synthesis of Multivalent Macromonomers for ROMP.

Authors:  Hung V-T Nguyen; Nolan M Gallagher; Farrukh Vohidov; Yivan Jiang; Ken Kawamoto; Hui Zhang; Jiwon V Park; Zhihao Huang; M Francesca Ottaviani; Andrzej Rajca; Jeremiah A Johnson
Journal:  ACS Macro Lett       Date:  2018-03-26       Impact factor: 6.903

Review 6.  pH-Sensitive stimulus-responsive nanocarriers for targeted delivery of therapeutic agents.

Authors:  Mahdi Karimi; Masoud Eslami; Parham Sahandi-Zangabad; Fereshteh Mirab; Negar Farajisafiloo; Zahra Shafaei; Deepanjan Ghosh; Mahnaz Bozorgomid; Fariba Dashkhaneh; Michael R Hamblin
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2016-01-14

7.  Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles.

Authors:  Andrew G Cheetham; Yu-Chuan Ou; Pengcheng Zhang; Honggang Cui
Journal:  Chem Commun (Camb)       Date:  2014-04-28       Impact factor: 6.222

8.  A pH-responsive prodrug delivery system of 10-HCPT for controlled release and tumor targeting.

Authors:  Yang Liu; Dan Li; Xinhong Guo; Haiwei Xu; Zhi Li; Yanling Zhang; Chuanjun Song; Ruhan Fan; Xing Tang; Zhenzhong Zhang
Journal:  Int J Nanomedicine       Date:  2017-03-22

9.  A multifunctional biodegradable brush polymer-drug conjugate for paclitaxel/gemcitabine co-delivery and tumor imaging.

Authors:  Haotian Sun; Lingyue Yan; Michael Yu Zarng Chang; Kevin A Carter; Runsheng Zhang; Leigh Slyker; Jonathan F Lovell; Yun Wu; Chong Cheng
Journal:  Nanoscale Adv       Date:  2019-05-27

10.  Synthesis, conjugating capacity and biocompatibility evaluation of a novel amphiphilic polynorbornene.

Authors:  Hengxi He; Bin Song; Guirong Qiu; Weixiang Wang; Haibin Gu
Journal:  Des Monomers Polym       Date:  2020-08-30       Impact factor: 2.650
  10 in total

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