Literature DB >> 24681886

The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity.

Xinyi Lu1, Friedrich Sachs2, LeeAnn Ramsay3, Pierre-Étienne Jacques4, Jonathan Göke1, Guillaume Bourque5, Huck-Hui Ng6.   

Abstract

Human endogenous retrovirus subfamily H (HERVH) is a class of transposable elements expressed preferentially in human embryonic stem cells (hESCs). Here, we report that the long terminal repeats of HERVH function as enhancers and that HERVH is a nuclear long noncoding RNA required to maintain hESC identity. Furthermore, HERVH is associated with OCT4, coactivators and Mediator subunits. Together, these results uncover a new role of species-specific transposable elements in hESCs.

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Year:  2014        PMID： 24681886     DOI： 10.1038/nsmb.2799

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


  26 in total

Review 1.  Extrinsic regulation of pluripotent stem cells.

Authors:  Martin F Pera; Patrick P L Tam
Journal:  Nature       Date:  2010-06-10       Impact factor: 49.962

2.  Java Treeview--extensible visualization of microarray data.

Authors:  Alok J Saldanha
Journal:  Bioinformatics       Date:  2004-06-04       Impact factor: 6.937

Review 3.  Structure and evolution of transcriptional regulatory networks.

Authors:  M Madan Babu; Nicholas M Luscombe; L Aravind; Mark Gerstein; Sarah A Teichmann
Journal:  Curr Opin Struct Biol       Date:  2004-06       Impact factor: 6.809

4.  Transposon-mediated rewiring of gene regulatory networks contributed to the evolution of pregnancy in mammals.

Authors:  Vincent J Lynch; Robert D Leclerc; Gemma May; Günter P Wagner
Journal:  Nat Genet       Date:  2011-09-25       Impact factor: 38.330

5.  Evolution of the mammalian transcription factor binding repertoire via transposable elements.

Authors:  Guillaume Bourque; Bernard Leong; Vinsensius B Vega; Xi Chen; Yen Ling Lee; Kandhadayar G Srinivasan; Joon-Lin Chew; Yijun Ruan; Chia-Lin Wei; Huck Hui Ng; Edison T Liu
Journal:  Genome Res       Date:  2008-08-05       Impact factor: 9.043

Review 6.  Transposable elements and the evolution of regulatory networks.

Authors:  Cédric Feschotte
Journal:  Nat Rev Genet       Date:  2008-05       Impact factor: 53.242

7.  Cluster analysis and display of genome-wide expression patterns.

Authors:  M B Eisen; P T Spellman; P O Brown; D Botstein
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

8.  The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression.

Authors:  Thomas Derrien; Rory Johnson; Giovanni Bussotti; Andrea Tanzer; Sarah Djebali; Hagen Tilgner; Gregory Guernec; David Martin; Angelika Merkel; David G Knowles; Julien Lagarde; Lavanya Veeravalli; Xiaoan Ruan; Yijun Ruan; Timo Lassmann; Piero Carninci; James B Brown; Leonard Lipovich; Jose M Gonzalez; Mark Thomas; Carrie A Davis; Ramin Shiekhattar; Thomas R Gingeras; Tim J Hubbard; Cedric Notredame; Jennifer Harrow; Roderic Guigó
Journal:  Genome Res       Date:  2012-09       Impact factor: 9.043

9.  GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists.

Authors:  Eran Eden; Roy Navon; Israel Steinfeld; Doron Lipson; Zohar Yakhini
Journal:  BMC Bioinformatics       Date:  2009-02-03       Impact factor: 3.169

10.  HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency.

Authors:  Federico A Santoni; Jessica Guerra; Jeremy Luban
Journal:  Retrovirology       Date:  2012-12-20       Impact factor: 4.602
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  157 in total

1.  Drawing a fine line on endogenous retroelement activity.

Authors:  Nathaly Castro-Diaz; Marc Friedli; Didier Trono
Journal:  Mob Genet Elements       Date:  2015-02-03

2.  Isolation and cultivation of naive-like human pluripotent stem cells based on HERVH expression.

Authors:  Jichang Wang; Manvendra Singh; Chuanbo Sun; Daniel Besser; Alessandro Prigione; Zoltán Ivics; Laurence D Hurst; Zsuzsanna Izsvák
Journal:  Nat Protoc       Date:  2016-01-21       Impact factor: 13.491

Review 3.  Molecular features of cellular reprogramming and development.

Authors:  Zachary D Smith; Camille Sindhu; Alexander Meissner
Journal:  Nat Rev Mol Cell Biol       Date:  2016-02-17       Impact factor: 94.444

4.  Viral Symbiosis in the Origins and Evolution of Life with a Particular Focus on the Placental Mammals.

Authors:  Frank Ryan
Journal:  Results Probl Cell Differ       Date:  2020

Review 5.  Retroviral transcriptional regulation and embryonic stem cells: war and peace.

Authors:  Sharon Schlesinger; Stephen P Goff
Journal:  Mol Cell Biol       Date:  2014-12-29       Impact factor: 4.272

6.  TEtranscripts: a package for including transposable elements in differential expression analysis of RNA-seq datasets.

Authors:  Ying Jin; Oliver H Tam; Eric Paniagua; Molly Hammell
Journal:  Bioinformatics       Date:  2015-07-23       Impact factor: 6.937

Review 7.  Silencing of endogenous retroviruses by heterochromatin.

Authors:  Sophia Groh; Gunnar Schotta
Journal:  Cell Mol Life Sci       Date:  2017-02-03       Impact factor: 9.261

Review 8.  Ground rules of the pluripotency gene regulatory network.

Authors:  Mo Li; Juan Carlos Izpisua Belmonte
Journal:  Nat Rev Genet       Date:  2017-01-03       Impact factor: 53.242

9.  Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway.

Authors:  Tongguang Wang; Marie Medynets; Kory R Johnson; Tara T Doucet-O'Hare; Brianna DiSanza; Wenxue Li; Yadi Xu; Anna Bagnell; Richa Tyagi; Kevon Sampson; Nasir Malik; Joseph Steiner; Alina Hadegan; Jeffrey Kowalak; James O'Malley; Dragan Maric; Avindra Nath
Journal:  Proc Natl Acad Sci U S A       Date:  2020-07-15       Impact factor: 11.205

10.  Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential.

Authors:  Mari Ohnuki; Koji Tanabe; Kenta Sutou; Ito Teramoto; Yuka Sawamura; Megumi Narita; Michiko Nakamura; Yumie Tokunaga; Masahiro Nakamura; Akira Watanabe; Shinya Yamanaka; Kazutoshi Takahashi
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-05       Impact factor: 11.205
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