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Literature DB >> 24602954

The effectiveness of routine daily chlorhexidine gluconate bathing in reducing Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae skin burden among long-term acute care hospital patients.

Michael Y Lin¹, Karen Lolans, Donald W Blom, Rosie D Lyles, Shayna Weiner, Kavya B Poluru, Nicholas Moore, David W Hines, Robert A Weinstein, Mary K Hayden.

Abstract

We evaluated the effectiveness of daily chlorhexidine gluconate (CHG) bathing in decreasing skin carriage of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae (KPC) among long-term acute care hospital patients. CHG bathing reduced KPC skin colonization, particularly when CHG skin concentrations greater than or equal to 128 μg/mL were achieved.

Entities: Chemical Disease Species

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Year: 2014 PMID： 24602954 DOI： 10.1086/675613

Source DB: PubMed Journal: Infect Control Hosp Epidemiol ISSN： 0899-823X Impact factor: 3.254

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Cited

17 in total

1. What's new in the prevention of healthcare-associated infections using chlorhexidine gluconate-impregnated washcloths.

Authors: Sandrine Dray; Jean-Marie Forel; Laurent Papazian
Journal: Intensive Care Med Date: 2018-11-26 Impact factor: 17.440

2. Emergence of carbapenem-resistant Enterobacteriaceae in Orange County, California, and support for early regional strategies to limit spread.

Authors: Shruti K Gohil; Raveena Singh; Justin Chang; Adrijana Gombosev; Tom Tjoa; Matthew Zahn; Patti Steger; Susan S Huang
Journal: Am J Infect Control Date: 2017-07-27 Impact factor: 2.918

3. Chlorhexidine versus routine bathing to prevent multidrug-resistant organisms and all-cause bloodstream infections in general medical and surgical units (ABATE Infection trial): a cluster-randomised trial.

Authors: Susan S Huang; Edward Septimus; Ken Kleinman; Julia Moody; Jason Hickok; Lauren Heim; Adrijana Gombosev; Taliser R Avery; Katherine Haffenreffer; Lauren Shimelman; Mary K Hayden; Robert A Weinstein; Caren Spencer-Smith; Rebecca E Kaganov; Michael V Murphy; Tyler Forehand; Julie Lankiewicz; Micaela H Coady; Lena Portillo; Jalpa Sarup-Patel; John A Jernigan; Jonathan B Perlin; Richard Platt
Journal: Lancet Date: 2019-03-05 Impact factor: 79.321

Review 10. Assessing the Potential for Unintended Microbial Consequences of Routine Chlorhexidine Bathing for Prevention of Healthcare-associated Infections.

Authors: Ahmed Babiker; Joseph D Lutgring; Scott Fridkin; Mary K Hayden
Journal: Clin Infect Dis Date: 2021-03-01 Impact factor: 9.079

The effectiveness of routine daily chlorhexidine gluconate bathing in reducing Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae skin burden among long-term acute care hospital patients.

1. What's new in the prevention of healthcare-associated infections using chlorhexidine gluconate-impregnated washcloths.

2. Emergence of carbapenem-resistant Enterobacteriaceae in Orange County, California, and support for early regional strategies to limit spread.

3. Chlorhexidine versus routine bathing to prevent multidrug-resistant organisms and all-cause bloodstream infections in general medical and surgical units (ABATE Infection trial): a cluster-randomised trial.

Review 4. Preventing Transmission of Multidrug-Resistant Pathogens in the Intensive Care Unit.

5. The impact of chlorhexidine gluconate on the skin microbiota of children and adults: A pilot study.

6. Insights into bacterial colonization of intensive care patients' skin: the effect of chlorhexidine daily bathing.

7. A Descriptive Study of Chlorhexidine as a Disinfectant in Cleft Palate Surgery.

Review 8. Decolonization in Prevention of Health Care-Associated Infections.

9. Impact of preoperative chlorhexidine gluconate (CHG) application methods on preoperative CHG skin concentration.

Review 10. Assessing the Potential for Unintended Microbial Consequences of Routine Chlorhexidine Bathing for Prevention of Healthcare-associated Infections.