Małgorzata Wierzbicka1, Mariola Popko1, Karolina Piskadło2, Rafał Czepczyński3, Aleksandra Stankowska2, Tomasz Piętka4, Mirosław Dziuk5, Witold Szyfter1. 1. Department of Otolaryngology, Poznan University of Medical Sciences, Poland. 2. Fifth Year Medical Faculty Student, Poznan University of Medical Sciences, Poland. 3. Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poland ; Department of PET/CT, Greater Poland Medical Centre, Poznan, Poland. 4. Department of Maxillofacial Surgery, Military Institute of Medicine, Warsaw, Poland. 5. Military Institute of Medicine and Masovian PET/CT Centre, Warsaw, Poland.
Abstract
BACKGROUND: Posttreatment surveillance for the local and regional recurrence of the head and neck squamous cell carcinoma often requires a multimodality techniques that include PET combined with CT, MRI, US. AIM: The purpose of this study is to compare the diagnostic performance of two imaging techniques (PET/CT and US), and their combined use for the detection of a subclinical regional recurrence in patients after HNSCC treatment. MATERIALS AND METHODS: 83 patients after completion of the HNSCC treatment underwent both US and PET/CT on the mean follow-up of 14 months after initial treatment. RESULTS: The sensitivity and specificity of PET/CT were 86% and 82%, respectively; US values reached 81% and 87%, respectively. PPV was 79% for PET/CT, and 83% for US. NPV was 89% for PET/CT, and 85% for US. The overall accuracy for PET/CT and US was 84% for both methods. CONCLUSION: US could be regarded as complementary to PET/CT as the procedures with highest sensitivity, specificity and NPV for detecting subclinical regional recurrences after HNSCC treatment.
BACKGROUND: Posttreatment surveillance for the local and regional recurrence of the head and neck squamous cell carcinoma often requires a multimodality techniques that include PET combined with CT, MRI, US. AIM: The purpose of this study is to compare the diagnostic performance of two imaging techniques (PET/CT and US), and their combined use for the detection of a subclinical regional recurrence in patients after HNSCC treatment. MATERIALS AND METHODS: 83 patients after completion of the HNSCC treatment underwent both US and PET/CT on the mean follow-up of 14 months after initial treatment. RESULTS: The sensitivity and specificity of PET/CT were 86% and 82%, respectively; US values reached 81% and 87%, respectively. PPV was 79% for PET/CT, and 83% for US. NPV was 89% for PET/CT, and 85% for US. The overall accuracy for PET/CT and US was 84% for both methods. CONCLUSION: US could be regarded as complementary to PET/CT as the procedures with highest sensitivity, specificity and NPV for detecting subclinical regional recurrences after HNSCC treatment.
Entities:
Keywords:
Head and neck squamous cell carcinoma; PET/CT; US
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