Literature DB >> 24320425

The impact of leaf width and plan complexity on DMLC tracking of prostate intensity modulated arc therapy.

Tobias Pommer1, Marianne Falk, Per Rugaard Poulsen, Paul J Keall, Ricky T O'Brien, Per Munck af Rosenschöld.   

Abstract

PURPOSE: Intensity modulated arc therapy (IMAT) is commonly used to treat prostate cancer. The purpose of this study was to evaluate the impact of leaf width and plan complexity on dynamic multileaf collimator (DMLC) tracking for prostate motion management during IMAT treatments.
METHODS: Prostate IMAT plans were delivered with either a high-definition MLC (HDMLC) or a Millennium MLC (M-MLC) (0.25 and 0.50 cm central leaf width, respectively), with and without DMLC tracking, to a dosimetric phantom that reproduced four prostate motion traces. The plan complexity was varied by applying leaf position constraints during plan optimization. A subset of the M-MLC plans was converted for delivery with the HDMLC, isolating the effect of the different leaf widths. The gamma index was used for evaluation. Tracking errors caused by target localization, leaf fitting, and leaf adjustment were analyzed.
RESULTS: The gamma pass rate was significantly improved with DMLC tracking compared to no tracking (p < 0.001). With DMLC tracking, the average gamma index pass rate was 98.6% (range 94.8%-100%) with the HDMLC and 98.1% (range 95.4%-99.7%) with the M-MLC, using 3%, 3 mm criteria and the planned dose as reference. The corresponding pass rates without tracking were 87.6% (range 76.2%-94.7%) and 91.1% (range 81.4%-97.6%), respectively. Decreased plan complexity improved the pass rate when static target measurements were used as reference, but not with the planned dose as reference. The main cause of tracking errors was leaf fitting errors, which were decreased by 42% by halving the leaf width.
CONCLUSIONS: DMLC tracking successfully compensated for the prostate motion. The finer leaf width of the HDMLC improved the tracking accuracy compared to the M-MLC. The tracking improvement with limited plan complexity was small and not discernible when using the planned dose as reference.

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Year:  2013        PMID: 24320425      PMCID: PMC3808441          DOI: 10.1118/1.4824434

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  18 in total

1.  Infrared patient positioning for stereotactic radiosurgery of extracranial tumors.

Authors:  L T Wang; T D Solberg; P M Medin; R Boone
Journal:  Comput Biol Med       Date:  2001-03       Impact factor: 4.589

2.  The dosimetric impact of inversely optimized arc radiotherapy plan modulation for real-time dynamic MLC tracking delivery.

Authors:  Marianne Falk; Tobias Larsson; Paul Keall; Byung Chul Cho; Marianne Aznar; Stine Korreman; Per Poulsen; Per Munck Af Rosenschold
Journal:  Med Phys       Date:  2012-03       Impact factor: 4.071

3.  Geometric accuracy of a real-time target tracking system with dynamic multileaf collimator tracking system.

Authors:  Paul J Keall; Herbert Cattell; Damodar Pokhrel; Sonja Dieterich; Kenneth H Wong; Martin J Murphy; S Sastry Vedam; Krishni Wijesooriya; Radhe Mohan
Journal:  Int J Radiat Oncol Biol Phys       Date:  2006-08-01       Impact factor: 7.038

4.  Multi-institutional clinical experience with the Calypso System in localization and continuous, real-time monitoring of the prostate gland during external radiotherapy.

Authors:  Patrick Kupelian; Twyla Willoughby; Arul Mahadevan; Toufik Djemil; Geoffrey Weinstein; Shirish Jani; Charles Enke; Timothy Solberg; Nicholas Flores; David Liu; David Beyer; Lisa Levine
Journal:  Int J Radiat Oncol Biol Phys       Date:  2006-12-21       Impact factor: 7.038

5.  Volumetric modulated arc therapy: IMRT in a single gantry arc.

Authors:  Karl Otto
Journal:  Med Phys       Date:  2008-01       Impact factor: 4.071

6.  Target-tracking deliveries using conventional multileaf collimators planned with 4D direct-aperture optimization.

Authors:  D McQuaid; S Webb
Journal:  Phys Med Biol       Date:  2008-07-08       Impact factor: 3.609

7.  Electromagnetic-guided dynamic multileaf collimator tracking enables motion management for intensity-modulated arc therapy.

Authors:  Paul J Keall; Amit Sawant; Byungchul Cho; Dan Ruan; Junqing Wu; Per Poulsen; Jay Petersen; Laurence J Newell; Herbert Cattell; Stine Korreman
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-07-07       Impact factor: 7.038

8.  Determination of action thresholds for electromagnetic tracking system-guided hypofractionated prostate radiotherapy using volumetric modulated arc therapy.

Authors:  Pengpeng Zhang; Dennis Mah; Laura Happersett; Brett Cox; Margie Hunt; Gig Mageras
Journal:  Med Phys       Date:  2011-07       Impact factor: 4.071

9.  Intrafraction prostate motion during IMRT for prostate cancer.

Authors:  Eugene Huang; Lei Dong; Anurag Chandra; Deborah A Kuban; Isaac I Rosen; Anissa Evans; Alan Pollack
Journal:  Int J Radiat Oncol Biol Phys       Date:  2002-06-01       Impact factor: 7.038

10.  Dosimetric benefit of DMLC tracking for conventional and sub-volume boosted prostate intensity-modulated arc radiotherapy.

Authors:  Tobias Pommer; Marianne Falk; Per R Poulsen; Paul J Keall; Ricky T O'Brien; Peter Meidahl Petersen; Per Munck af Rosenschöld
Journal:  Phys Med Biol       Date:  2013-03-14       Impact factor: 3.609

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  2 in total

1.  Technical Note: In silico and experimental evaluation of two leaf-fitting algorithms for MLC tracking based on exposure error and plan complexity.

Authors:  Vincent Caillet; Ricky O'Brien; Douglas Moore; Per Poulsen; Tobias Pommer; Emma Colvill; Amit Sawant; Jeremy Booth; Paul Keall
Journal:  Med Phys       Date:  2019-03-04       Impact factor: 4.071

Review 2.  Image-guided radiotherapy and motion management in lung cancer.

Authors:  S S Korreman
Journal:  Br J Radiol       Date:  2015-05-08       Impact factor: 3.039

  2 in total

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