Literature DB >> 24123712

Quantitative measurement of femoral condyle cartilage in the knee by MRI: validation study by multireaders.

Yasunari Fujinaga1, Hiroshi Yoshioka, Toshinori Sakai, Yoko Sakai, Felipe Souza, Philipp Lang.   

Abstract

PURPOSE: To determine reproducibility of the femoral condyle cartilage volume (CV) in cross-sectional and longitudinal studies using various 3D imaging techniques at 1.5 T and 3 T.
MATERIALS AND METHODS: In 21 subjects with osteoarthritis, magnetic resonance imaging (MRI) including four different sequences (sagittal 3D fat suppressed spoiled gradient-echo [SPGR] at 1.5 T, fat suppressed fast low angle shot [FLASH] at 3 T, water-excitation dual echo steady state [DESS] at 3 T, and water-excitation multiecho data image combination [MEDIC] at 3 T) were acquired at baseline and ∼1 year later. The CV measured using semiautomated segmentation software by three readers was analyzed.
RESULTS: The mean of the interclass correlation coefficient between each reader from SPGR, FLASH, DESS, and MEDIC was 0.899, 0.948, 0.943, and 0.954, respectively. The mean CV (×10(4) mm(3) ) measured by each reader from SPGR/FLASH/DESS/MEDIC sequences was the following in this order: 1.34/1.52/1.50/1.35, 1.21/1.43/1.40/1.27, 1.22/1.37/1.36/1.22, and 1.17/1.36/1.35/1.21 by readers 1, 2, 3 (first analysis), and 3 (second analysis), respectively. There was no statistically significant difference in CV between any readers in any sequences. The CV measured on FLASH and DESS tended to be greater than that on SPGR or MEDIC.
CONCLUSION: Inter- and intraobserver reproducibility of cartilage segmentation using semiautomated software was validated. Although there was no statistical significance, there was a tendency of under- or overestimating CV by each sequence.
Copyright © 2013 Wiley Periodicals, Inc.

Entities:  

Keywords:  knee cartilage; magnetic resonance imaging; reproducibility; segmentation

Mesh:

Year:  2013        PMID: 24123712      PMCID: PMC3962518          DOI: 10.1002/jmri.24217

Source DB:  PubMed          Journal:  J Magn Reson Imaging        ISSN: 1053-1807            Impact factor:   4.813


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