Literature DB >> 23885144

Optical diagnosis of colorectal polyps using high-definition i-scan: an educational experience.

Mariëlle W E Bouwens1, Rogier de Ridder, Ad A M Masclee, Ann Driessen, Robert G Riedl, Bjorn Winkens, Silvia Sanduleanu.   

Abstract

AIM: To examine performances regarding prediction of polyp histology using high-definition (HD) i-scan in a group of endoscopists with varying levels of experience.
METHODS: We used a digital library of HD i-scan still images, comprising twin pictures (surface enhancement and tone enhancement), collected at our university hospital. We defined endoscopic features of adenomatous and non-adenomatous polyps, according to the following parameters: color, surface pattern and vascular pattern. We familiarized the participating endoscopists on optical diagnosis of colorectal polyps using a 20-min didactic training session. All endoscopists were asked to evaluate an image set of 50 colorectal polyps with regard to polyp histology. We classified the diagnoses into high confidence (i.e., cases in which the endoscopist could assign a diagnosis with certainty) and low confidence diagnoses (i.e., cases in which the endoscopist preferred to send the polyp for formal histology). Mean sensitivity, specificity and accuracy per endoscopist/image were computed and differences between groups tested using independent-samples t tests. High vs low confidence diagnoses were compared using the paired-samples t test.
RESULTS: Eleven endoscopists without previous experience on optical diagnosis evaluated a total of 550 images (396 adenomatous, 154 non-adenomatous). Mean sensitivity, specificity and accuracy for diagnosing adenomas were 79.3%, 85.7% and 81.1%, respectively. No significant differences were found between gastroenterologists and trainees regarding performances of optical diagnosis (mean accuracy 78.0% vs 82.9%, P = 0.098). Diminutive lesions were predicted with a lower mean accuracy as compared to non-diminutive lesions (74.2% vs 93.1%, P = 0.008). A total of 446 (81.1%) diagnoses were made with high confidence. High confidence diagnoses corresponded to a significantly higher mean accuracy than low confidence diagnoses (84.0% vs 64.3%, P = 0.008). A total of 319 (58.0%) images were evaluated as having excellent quality. Considering excellent quality images in conjunction with high confidence diagnosis, overall accuracy increased to 92.8%.
CONCLUSION: After a single training session, endoscopists with varying levels of experience can already provide optical diagnosis with an accuracy of 84.0%.

Entities:  

Keywords:  Colonoscopy; Colorectal polyps; High-definition i-scan; Optical diagnosis; Training

Mesh:

Year:  2013        PMID: 23885144      PMCID: PMC3718901          DOI: 10.3748/wjg.v19.i27.4334

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  44 in total

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8.  Randomized, controlled trial of standard-definition white-light, high-definition white-light, and narrow-band imaging colonoscopy for the detection of colon polyps and prediction of polyp histology.

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10.  Pancolonic chromoendoscopy with indigo carmine versus standard colonoscopy for detection of neoplastic lesions: a randomised two-centre trial.

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Authors:  Timo Rath; Gian Eugenio Tontini; Markus F Neurath; Helmut Neumann
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Review 2.  Advanced gastrointestinal endoscopic imaging for inflammatory bowel diseases.

Authors:  Gian Eugenio Tontini; Timo Rath; Helmut Neumann
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3.  Detection and characterization of colorectal polyps using high-definition white light and i-Scan: Evidence-based consensus recommendations using a modified Delphi process.

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4.  Accuracy of i-Scan for Optical Diagnosis of Colonic Polyps: A Meta-Analysis.

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5.  Optical diagnosis of malignant colorectal polyps: is it feasible?

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6.  Partial Oxygen Pressure Affects the Expression of Prognostic Biomarkers HIF-1 Alpha, Ki67, and CK20 in the Microenvironment of Colorectal Cancer Tissue.

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7.  High-definition endoscopy with digital chromoendoscopy for histologic prediction of distal colorectal polyps.

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8.  I-scan optical enhancement for the in vivo prediction of diminutive colorectal polyp histology: Results from a prospective three-phased multicentre trial.

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  8 in total

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