Literature DB >> 23558168

Comprehensive temporal information detection from clinical text: medical events, time, and TLINK identification.

Sunghwan Sohn1, Kavishwar B Wagholikar, Dingcheng Li, Siddhartha R Jonnalagadda, Cui Tao, Ravikumar Komandur Elayavilli, Hongfang Liu.   

Abstract

BACKGROUND: Temporal information detection systems have been developed by the Mayo Clinic for the 2012 i2b2 Natural Language Processing Challenge.
OBJECTIVE: To construct automated systems for EVENT/TIMEX3 extraction and temporal link (TLINK) identification from clinical text.
MATERIALS AND METHODS: The i2b2 organizers provided 190 annotated discharge summaries as the training set and 120 discharge summaries as the test set. Our Event system used a conditional random field classifier with a variety of features including lexical information, natural language elements, and medical ontology. The TIMEX3 system employed a rule-based method using regular expression pattern match and systematic reasoning to determine normalized values. The TLINK system employed both rule-based reasoning and machine learning. All three systems were built in an Apache Unstructured Information Management Architecture framework.
RESULTS: Our TIMEX3 system performed the best (F-measure of 0.900, value accuracy 0.731) among the challenge teams. The Event system produced an F-measure of 0.870, and the TLINK system an F-measure of 0.537.
CONCLUSIONS: Our TIMEX3 system demonstrated good capability of regular expression rules to extract and normalize time information. Event and TLINK machine learning systems required well-defined feature sets to perform well. We could also leverage expert knowledge as part of the machine learning features to further improve TLINK identification performance.

Entities:  

Mesh:

Year:  2013        PMID: 23558168      PMCID: PMC3756269          DOI: 10.1136/amiajnl-2013-001622

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  11 in total

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2.  Coreference analysis in clinical notes: a multi-pass sieve with alternate anaphora resolution modules.

Authors:  Siddhartha Reddy Jonnalagadda; Dingcheng Li; Sunghwan Sohn; Stephen Tze-Inn Wu; Kavishwar Wagholikar; Manabu Torii; Hongfang Liu
Journal:  J Am Med Inform Assoc       Date:  2012-06-16       Impact factor: 4.497

3.  Mayo clinic smoking status classification system: extensions and improvements.

Authors:  Sunghwan Sohn; Guergana K Savova
Journal:  AMIA Annu Symp Proc       Date:  2009-11-14

4.  Using machine learning for concept extraction on clinical documents from multiple data sources.

Authors:  Manabu Torii; Kavishwar Wagholikar; Hongfang Liu
Journal:  J Am Med Inform Assoc       Date:  2011-06-27       Impact factor: 4.497

5.  2010 i2b2/VA challenge on concepts, assertions, and relations in clinical text.

Authors:  Özlem Uzuner; Brett R South; Shuying Shen; Scott L DuVall
Journal:  J Am Med Inform Assoc       Date:  2011-06-16       Impact factor: 4.497

6.  CNTRO: A Semantic Web Ontology for Temporal Relation Inferencing in Clinical Narratives.

Authors:  Cui Tao; Wei-Qi Wei; Harold R Solbrig; Guergana Savova; Christopher G Chute
Journal:  AMIA Annu Symp Proc       Date:  2010-11-13

7.  Drug side effect extraction from clinical narratives of psychiatry and psychology patients.

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8.  Feasibility of pooling annotated corpora for clinical concept extraction.

Authors:  Kavishwar Wagholikar; Manabu Torii; Siddhartha Jonnalagadda; Hongfang Liu
Journal:  AMIA Jt Summits Transl Sci Proc       Date:  2012-03-19

9.  Pooling annotated corpora for clinical concept extraction.

Authors:  Kavishwar B Wagholikar; Manabu Torii; Siddhartha R Jonnalagadda; Hongfang Liu
Journal:  J Biomed Semantics       Date:  2013-01-08

10.  CNTRO 2.0: A Harmonized Semantic Web Ontology for Temporal Relation Inferencing in Clinical Narratives.

Authors:  Cui Tao; Harold R Solbrig; Christopher G Chute
Journal:  AMIA Jt Summits Transl Sci Proc       Date:  2011-03-07
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  23 in total

1.  Electronic health records-driven phenotyping: challenges, recent advances, and perspectives.

Authors:  Jyotishman Pathak; Abel N Kho; Joshua C Denny
Journal:  J Am Med Inform Assoc       Date:  2013-12       Impact factor: 4.497

2.  Normalization of relative and incomplete temporal expressions in clinical narratives.

Authors:  Weiyi Sun; Anna Rumshisky; Ozlem Uzuner
Journal:  J Am Med Inform Assoc       Date:  2015-04-12       Impact factor: 4.497

3.  Time event ontology (TEO): to support semantic representation and reasoning of complex temporal relations of clinical events.

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Journal:  J Am Med Inform Assoc       Date:  2020-07-01       Impact factor: 4.497

4.  CMedTEX: A Rule-based Temporal Expression Extraction and Normalization System for Chinese Clinical Notes.

Authors:  Zengjian Liu; Buzhou Tang; Xiaolong Wang; Qingcai Chen; Haodi Li; Junzhao Bu; Jingzhi Jiang; Qiwen Deng; Suisong Zhu
Journal:  AMIA Annu Symp Proc       Date:  2017-02-10

5.  Automatic identification of methotrexate-induced liver toxicity in patients with rheumatoid arthritis from the electronic medical record.

Authors:  Chen Lin; Elizabeth W Karlson; Dmitriy Dligach; Monica P Ramirez; Timothy A Miller; Huan Mo; Natalie S Braggs; Andrew Cagan; Vivian Gainer; Joshua C Denny; Guergana K Savova
Journal:  J Am Med Inform Assoc       Date:  2014-10-25       Impact factor: 4.497

6.  Correlating Lab Test Results in Clinical Notes with Structured Lab Data: A Case Study in HbA1c and Glucose.

Authors:  Sijia Liu; Liwei Wang; Donna Ihrke; Vipin Chaudhary; Cui Tao; Chunhua Weng; Hongfang Liu
Journal:  AMIA Jt Summits Transl Sci Proc       Date:  2017-07-26

7.  Methodological variations in lagged regression for detecting physiologic drug effects in EHR data.

Authors:  Matthew E Levine; David J Albers; George Hripcsak
Journal:  J Biomed Inform       Date:  2018-08-30       Impact factor: 6.317

8.  A pattern learning-based method for temporal expression extraction and normalization from multi-lingual heterogeneous clinical texts.

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9.  Achievability to Extract Specific Date Information for Cancer Research.

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Review 10.  Evaluating temporal relations in clinical text: 2012 i2b2 Challenge.

Authors:  Weiyi Sun; Anna Rumshisky; Ozlem Uzuner
Journal:  J Am Med Inform Assoc       Date:  2013-04-05       Impact factor: 4.497

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