Literature DB >> 25868462

Normalization of relative and incomplete temporal expressions in clinical narratives.

Weiyi Sun1, Anna Rumshisky2, Ozlem Uzuner3.   

Abstract

OBJECTIVE: To improve the normalization of relative and incomplete temporal expressions (RI-TIMEXes) in clinical narratives.
METHODS: We analyzed the RI-TIMEXes in temporally annotated corpora and propose two hypotheses regarding the normalization of RI-TIMEXes in the clinical narrative domain: the anchor point hypothesis and the anchor relation hypothesis. We annotated the RI-TIMEXes in three corpora to study the characteristics of RI-TMEXes in different domains. This informed the design of our RI-TIMEX normalization system for the clinical domain, which consists of an anchor point classifier, an anchor relation classifier, and a rule-based RI-TIMEX text span parser. We experimented with different feature sets and performed an error analysis for each system component.
RESULTS: The annotation confirmed the hypotheses that we can simplify the RI-TIMEXes normalization task using two multi-label classifiers. Our system achieves anchor point classification, anchor relation classification, and rule-based parsing accuracy of 74.68%, 87.71%, and 57.2% (82.09% under relaxed matching criteria), respectively, on the held-out test set of the 2012 i2b2 temporal relation challenge. DISCUSSION: Experiments with feature sets reveal some interesting findings, such as: the verbal tense feature does not inform the anchor relation classification in clinical narratives as much as the tokens near the RI-TIMEX. Error analysis showed that underrepresented anchor point and anchor relation classes are difficult to detect.
CONCLUSIONS: We formulate the RI-TIMEX normalization problem as a pair of multi-label classification problems. Considering only RI-TIMEX extraction and normalization, the system achieves statistically significant improvement over the RI-TIMEX results of the best systems in the 2012 i2b2 challenge.
© The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  medical language processing; temporal expression normalization; temporal reasoning

Mesh:

Year:  2015        PMID: 25868462      PMCID: PMC4986666          DOI: 10.1093/jamia/ocu004

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  13 in total

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Review 6.  Temporal reasoning over clinical text: the state of the art.

Authors:  Weiyi Sun; Anna Rumshisky; Ozlem Uzuner
Journal:  J Am Med Inform Assoc       Date:  2013-05-15       Impact factor: 4.497

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Authors:  Weiyi Sun; Anna Rumshisky; Ozlem Uzuner
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Review 9.  Evaluating temporal relations in clinical text: 2012 i2b2 Challenge.

Authors:  Weiyi Sun; Anna Rumshisky; Ozlem Uzuner
Journal:  J Am Med Inform Assoc       Date:  2013-04-05       Impact factor: 4.497

10.  Combining rules and machine learning for extraction of temporal expressions and events from clinical narratives.

Authors:  Aleksandar Kovacevic; Azad Dehghan; Michele Filannino; John A Keane; Goran Nenadic
Journal:  J Am Med Inform Assoc       Date:  2013-04-20       Impact factor: 4.497

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