Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Mechanics of dynamin-mediated membrane fission.

Literature DB >> 23541160

Mechanics of dynamin-mediated membrane fission.

Abstract

In eukaryotic cells, membrane compartments are split into two by membrane fission. This ensures discontinuity of membrane containers and thus proper compartmentalization. The first proteic machinery implicated in catalyzing membrane fission was dynamin. Dynamin forms helical collars at the neck of endocytic buds. This structural feature suggested that the helix of dynamin could constrict in order to promote fission of the enclosed membrane. However, verifying this hypothesis revealed itself to be a challenge, which inspired many in vitro and in vivo studies. The primary goal of this review is to discuss recent structural and physical data from biophysical studies that have refined our understanding of the dynamin mechanism. In addition to the constriction hypothesis, other models have been proposed to explain how dynamin induces membrane fission. We present experimental data supporting these various models and assess which model is the most probable.

Entities: Chemical

Mesh：

Substances：
Dynamins

Year: 2013 PMID： 23541160 PMCID： PMC4289195 DOI： 10.1146/annurev-biophys-050511-102247

Source DB: PubMed Journal: Annu Rev Biophys ISSN： 1936-122X Impact factor: 12.981

86 in total

1. BAR domains as sensors of membrane curvature: the amphiphysin BAR structure.

Authors: Brian J Peter; Helen M Kent; Ian G Mills; Yvonne Vallis; P Jonathan G Butler; Philip R Evans; Harvey T McMahon
Journal: Science Date: 2003-11-26 Impact factor: 47.728

2. Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins.

Authors: Toshiki Itoh; Kai S Erdmann; Aurelien Roux; Bianca Habermann; Hauke Werner; Pietro De Camilli
Journal: Dev Cell Date: 2005-12 Impact factor: 12.270

3. Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins.

Authors: R A Obar; C A Collins; J A Hammarback; H S Shpetner; R B Vallee
Journal: Nature Date: 1990-09-20 Impact factor: 49.962

4. Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA.

Authors: T-G Iversen; G Skretting; B van Deurs; K Sandvig
Journal: Proc Natl Acad Sci U S A Date: 2003-04-07 Impact factor: 11.205

5. A dynamin GTPase mutation causes a rapid and reversible temperature-inducible locomotion defect in C. elegans.

Authors: S G Clark; D L Shurland; E M Meyerowitz; C I Bargmann; A M van der Bliek
Journal: Proc Natl Acad Sci U S A Date: 1997-09-16 Impact factor: 11.205

6. Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis.

Authors: K Takei; V I Slepnev; V Haucke; P De Camilli
Journal: Nat Cell Biol Date: 1999-05 Impact factor: 28.824

7. Dynamin is a GTPase stimulated to high levels of activity by microtubules.

Authors: H S Shpetner; R B Vallee
Journal: Nature Date: 1992-02-20 Impact factor: 49.962

8. Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells.

Authors: Jeffrey B Doyon; Bryan Zeitler; Jackie Cheng; Aaron T Cheng; Jennifer M Cherone; Yolanda Santiago; Andrew H Lee; Thuy D Vo; Yannick Doyon; Jeffrey C Miller; David E Paschon; Lei Zhang; Edward J Rebar; Philip D Gregory; Fyodor D Urnov; David G Drubin
Journal: Nat Cell Biol Date: 2011-02-06 Impact factor: 28.824

9. Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion.

Authors: Rachel M DeVay; Lenin Dominguez-Ramirez; Laura L Lackner; Suzanne Hoppins; Henning Stahlberg; Jodi Nunnari
Journal: J Cell Biol Date: 2009-09-14 Impact factor: 10.539

10. Mutations in human dynamin block an intermediate stage in coated vesicle formation.

Authors: A M van der Bliek; T E Redelmeier; H Damke; E J Tisdale; E M Meyerowitz; S L Schmid
Journal: J Cell Biol Date: 1993-08 Impact factor: 10.539

58 in total

1. Identification and function of conformational dynamics in the multidomain GTPase dynamin.

Authors: Saipraveen Srinivasan; Venkatasubramanian Dharmarajan; Dana Kim Reed; Patrick R Griffin; Sandra L Schmid
Journal: EMBO J Date: 2016-01-18 Impact factor: 11.598

2. Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal.

Authors: Bianca Schulte; Cindy Buffone; Silvana Opp; Francesca Di Nunzio; Daniel Augusto De Souza Aranha Vieira; Alberto Brandariz-Nuñez; Felipe Diaz-Griffero
Journal: J Virol Date: 2015-06-10 Impact factor: 5.103

Mechanics of dynamin-mediated membrane fission.

1. BAR domains as sensors of membrane curvature: the amphiphysin BAR structure.

2. Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins.

3. Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins.

4. Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA.

5. A dynamin GTPase mutation causes a rapid and reversible temperature-inducible locomotion defect in C. elegans.

6. Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis.

7. Dynamin is a GTPase stimulated to high levels of activity by microtubules.

8. Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells.

9. Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion.

10. Mutations in human dynamin block an intermediate stage in coated vesicle formation.

1. Identification and function of conformational dynamics in the multidomain GTPase dynamin.

2. Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal.

3. Ancient dynamin segments capture early stages of host-mitochondrial integration.

4. The tilted helix model of dynamin oligomers.

5. Dynamic remodeling of the dynamin helix during membrane constriction.

6. Constriction by Dynamin: Elasticity versus Adhesion.

7. Contribution of MxB oligomerization to HIV-1 capsid binding and restriction.

Review 8. Dynamin assembly strategies and adaptor proteins in mitochondrial fission.

Review 9. Molecular structure, function, and dynamics of clathrin-mediated membrane traffic.

10. Membrane scission driven by the PROPPIN Atg18.