Literature DB >> 23467472

An end-to-end system to identify temporal relation in discharge summaries: 2012 i2b2 challenge.

Yan Xu1, Yining Wang, Tianren Liu, Junichi Tsujii, Eric I-Chao Chang.   

Abstract

OBJECTIVE: To create an end-to-end system to identify temporal relation in discharge summaries for the 2012 i2b2 challenge. The challenge includes event extraction, timex extraction, and temporal relation identification.
DESIGN: An end-to-end temporal relation system was developed. It includes three subsystems: an event extraction system (conditional random fields (CRF) name entity extraction and their corresponding attribute classifiers), a temporal extraction system (CRF name entity extraction, their corresponding attribute classifiers, and context-free grammar based normalization system), and a temporal relation system (10 multi-support vector machine (SVM) classifiers and a Markov logic networks inference system) using labeled sequential pattern mining, syntactic structures based on parse trees, and results from a coordination classifier. Micro-averaged precision (P), recall (R), averaged P&R (P&R), and F measure (F) were used to evaluate results.
RESULTS: For event extraction, the system achieved 0.9415 (P), 0.8930 (R), 0.9166 (P&R), and 0.9166 (F). The accuracies of their type, polarity, and modality were 0.8574, 0.8585, and 0.8560, respectively. For timex extraction, the system achieved 0.8818, 0.9489, 0.9141, and 0.9141, respectively. The accuracies of their type, value, and modifier were 0.8929, 0.7170, and 0.8907, respectively. For temporal relation, the system achieved 0.6589, 0.7129, 0.6767, and 0.6849, respectively. For end-to-end temporal relation, it achieved 0.5904, 0.5944, 0.5921, and 0.5924, respectively. With the F measure used for evaluation, we were ranked first out of 14 competing teams (event extraction), first out of 14 teams (timex extraction), third out of 12 teams (temporal relation), and second out of seven teams (end-to-end temporal relation).
CONCLUSIONS: The system achieved encouraging results, demonstrating the feasibility of the tasks defined by the i2b2 organizers. The experiment result demonstrates that both global and local information is useful in the 2012 challenge.

Entities:  

Keywords:  Context-Free Grammar; Coordination; Dependency Tree; Labeled Sequential Pattern; Syntax

Mesh:

Year:  2013        PMID: 23467472      PMCID: PMC3756267          DOI: 10.1136/amiajnl-2012-001607

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  5 in total

1.  System architecture for temporal information extraction, representation and reasoning in clinical narrative reports.

Authors:  Li Zhou; Carol Friedman; Simon Parsons; George Hripcsak
Journal:  AMIA Annu Symp Proc       Date:  2005

2.  Feature engineering combined with machine learning and rule-based methods for structured information extraction from narrative clinical discharge summaries.

Authors:  Yan Xu; Kai Hong; Junichi Tsujii; Eric I-Chao Chang
Journal:  J Am Med Inform Assoc       Date:  2012-05-14       Impact factor: 4.497

3.  Evaluation of a method to identify and categorize section headers in clinical documents.

Authors:  Joshua C Denny; Anderson Spickard; Kevin B Johnson; Neeraja B Peterson; Josh F Peterson; Randolph A Miller
Journal:  J Am Med Inform Assoc       Date:  2009-08-28       Impact factor: 4.497

4.  Extracting timing and status descriptors for colonoscopy testing from electronic medical records.

Authors:  Joshua C Denny; Josh F Peterson; Neesha N Choma; Hua Xu; Randolph A Miller; Lisa Bastarache; Neeraja B Peterson
Journal:  J Am Med Inform Assoc       Date:  2010 Jul-Aug       Impact factor: 4.497

Review 5.  Evaluating temporal relations in clinical text: 2012 i2b2 Challenge.

Authors:  Weiyi Sun; Anna Rumshisky; Ozlem Uzuner
Journal:  J Am Med Inform Assoc       Date:  2013-04-05       Impact factor: 4.497

  5 in total
  19 in total

1.  Multilayered temporal modeling for the clinical domain.

Authors:  Chen Lin; Dmitriy Dligach; Timothy A Miller; Steven Bethard; Guergana K Savova
Journal:  J Am Med Inform Assoc       Date:  2015-10-31       Impact factor: 4.497

2.  Electronic health records-driven phenotyping: challenges, recent advances, and perspectives.

Authors:  Jyotishman Pathak; Abel N Kho; Joshua C Denny
Journal:  J Am Med Inform Assoc       Date:  2013-12       Impact factor: 4.497

3.  Normalization of relative and incomplete temporal expressions in clinical narratives.

Authors:  Weiyi Sun; Anna Rumshisky; Ozlem Uzuner
Journal:  J Am Med Inform Assoc       Date:  2015-04-12       Impact factor: 4.497

4.  CMedTEX: A Rule-based Temporal Expression Extraction and Normalization System for Chinese Clinical Notes.

Authors:  Zengjian Liu; Buzhou Tang; Xiaolong Wang; Qingcai Chen; Haodi Li; Junzhao Bu; Jingzhi Jiang; Qiwen Deng; Suisong Zhu
Journal:  AMIA Annu Symp Proc       Date:  2017-02-10

5.  Towards a Generalizable Time Expression Model for Temporal Reasoning in Clinical Notes.

Authors:  Sumithra Velupillai; Danielle L Mowery; Samir Abdelrahman; Lee Christensen; Wendy W Chapman
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Authors:  Chen Lin; Elizabeth W Karlson; Dmitriy Dligach; Monica P Ramirez; Timothy A Miller; Huan Mo; Natalie S Braggs; Andrew Cagan; Vivian Gainer; Joshua C Denny; Guergana K Savova
Journal:  J Am Med Inform Assoc       Date:  2014-10-25       Impact factor: 4.497

7.  Classifying temporal relations in clinical data: a hybrid, knowledge-rich approach.

Authors:  Jennifer D'Souza; Vincent Ng
Journal:  J Biomed Inform       Date:  2013-08-14       Impact factor: 6.317

8.  A pattern learning-based method for temporal expression extraction and normalization from multi-lingual heterogeneous clinical texts.

Authors:  Tianyong Hao; Xiaoyi Pan; Zhiying Gu; Yingying Qu; Heng Weng
Journal:  BMC Med Inform Decis Mak       Date:  2018-03-22       Impact factor: 2.796

9.  Achievability to Extract Specific Date Information for Cancer Research.

Authors:  Liwei Wang; Jason Wampfler; Angela Dispenzieri; Hua Xu; Ping Yang; Hongfang Liu
Journal:  AMIA Annu Symp Proc       Date:  2020-03-04

Review 10.  Evaluating temporal relations in clinical text: 2012 i2b2 Challenge.

Authors:  Weiyi Sun; Anna Rumshisky; Ozlem Uzuner
Journal:  J Am Med Inform Assoc       Date:  2013-04-05       Impact factor: 4.497

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