| Literature DB >> 23459485 |
Tatsuya Tada1, Tohru Miyoshi-Akiyama, Rajan K Dahal, Manoj K Sah, Hiroshi Ohara, Teruo Kirikae, Bharat M Pokhrel.
Abstract
A novel metallo-β-lactamase, NDM-8, was identified in a multidrug-resistant Escherichia coli isolate, IOMTU11 (NCGM37), obtained from the respiratory tract of a patient in Nepal. The amino acid sequence of NDM-8 has substitutions at positions 130 (Asp to Gly) and 154 (Met to Leu) compared with NDM-1. NDM-8 showed enzymatic activities against β-lactams similar to those of NDM-1.Entities:
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Year: 2013 PMID: 23459485 PMCID: PMC3632942 DOI: 10.1128/AAC.02553-12
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191