Literature DB >> 23379262

Fixable or fate? Perceptions of the biology of depression.

Matthew S Lebowitz1, Woo-Kyoung Ahn, Susan Nolen-Hoeksema.   

Abstract

OBJECTIVE: Previous research has shown that biological (e.g., genetic, biochemical) accounts of depression--currently in ascendancy--are linked to the general public's pessimism about the syndrome's prognosis. This research examined for the first time whether people with depressive symptoms would associate biological accounts of depression with pessimism about their own prognoses and whether a psychoeducation intervention portraying the biology of depression as malleable could decrease prognostic pessimism among symptomatic individuals.
METHOD: In 3 studies, participants were recruited online and assessed for depression symptoms. Those with significant depressive symptomatology (a Beck Depression Inventory-II score of at least 16) rated their endorsement of biochemical and genetic causal attributions for their symptoms and indicated expected length of symptom duration. An audiovisual intervention emphasizing the malleability of gene effects and neurochemistry was developed, and its effects on symptomatic individuals' prognostic pessimism, feelings of agency, guilt, and general hopelessness were measured.
RESULTS: Biochemical and genetic causal attributions for depression were significantly associated with prognostic pessimism among symptomatic individuals. The malleability intervention significantly reduced prognostic pessimism, increased feelings of agency, and decreased general hopelessness.
CONCLUSIONS: Biochemical and genetic attributions for depression are related to prognostic pessimism among individuals with depressive symptoms, and not just among the general public. However, emphasizing the malleability of gene effects and brain chemistry in depression can foster more optimism about depression-related beliefs.

Entities:  

Mesh:

Year:  2013        PMID: 23379262      PMCID: PMC3958946          DOI: 10.1037/a0031730

Source DB:  PubMed          Journal:  J Consult Clin Psychol        ISSN: 0022-006X


  18 in total

1.  Implicit theories of intelligence predict achievement across an adolescent transition: a longitudinal study and an intervention.

Authors:  Lisa S Blackwell; Kali H Trzesniewski; Carol Sorich Dweck
Journal:  Child Dev       Date:  2007 Jan-Feb

2.  Geneticization of deviant behavior and consequences for stigma: the case of mental illness.

Authors:  Jo C Phelan
Journal:  J Health Soc Behav       Date:  2005-12

3.  Genetic essentialism, neuroessentialism, and stigma: commentary on Dar-Nimrod and Heine (2011).

Authors:  Nick Haslam
Journal:  Psychol Bull       Date:  2011-09       Impact factor: 17.737

Review 4.  "A gene for...": the nature of gene action in psychiatric disorders.

Authors:  Kenneth S Kendler
Journal:  Am J Psychiatry       Date:  2005-07       Impact factor: 18.112

5.  The measurement of pessimism: the hopelessness scale.

Authors:  A T Beck; A Weissman; D Lester; L Trexler
Journal:  J Consult Clin Psychol       Date:  1974-12

6.  In genes we trust: the biological component of psychological essentialism and its relationship to mechanisms of motivated social cognition.

Authors:  Johannes Keller
Journal:  J Pers Soc Psychol       Date:  2005-04

7.  Amazon's Mechanical Turk: A New Source of Inexpensive, Yet High-Quality, Data?

Authors:  Michael Buhrmester; Tracy Kwang; Samuel D Gosling
Journal:  Perspect Psychol Sci       Date:  2011-02-03

Review 8.  Health beliefs and perceived need for mental health care of anxiety and depression--the patients' perspective explored.

Authors:  Marijn A Prins; Peter F M Verhaak; Jozien M Bensing; Klaas van der Meer
Journal:  Clin Psychol Rev       Date:  2008-03-07

9.  Effects of attributing serious mental illnesses to genetic causes on orientations to treatment.

Authors:  Jo C Phelan; Lawrence H Yang; Rosangely Cruz-Rojas
Journal:  Psychiatr Serv       Date:  2006-03       Impact factor: 3.084

10.  The stigmatising implications of presenting schizophrenia as a genetic disease.

Authors:  Laura Bennett; Kathryn Thirlaway; Alexandra J Murray
Journal:  J Genet Couns       Date:  2008-09-05       Impact factor: 2.537

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  31 in total

1.  Beyond the Dichotomy: Modernizing Stigma Categorization.

Authors:  Sierra B Cronan; Karen D Key; Allison A Vaughn
Journal:  Stigma Health       Date:  2016-03-14

2.  Words will never hurt me? Preferred terms for describing obesity and binge eating.

Authors:  J A Lydecker; K Galbraith; V Ivezaj; M A White; R D Barnes; C A Roberto; C M Grilo
Journal:  Int J Clin Pract       Date:  2016-06-28       Impact factor: 2.503

3.  "I Can't Crack the Code": What Suicide Notes Teach Us about Experiences with Mental Illness and Mental Health Care.

Authors:  Zainab Furqan; Mark Sinyor; Ayal Schaffer; Paul Kurdyak; Juveria Zaheer
Journal:  Can J Psychiatry       Date:  2018-07-16       Impact factor: 4.356

4.  Impact of melanoma genetic test reporting on perceived control over melanoma prevention.

Authors:  Lisa G Aspinwall; Tammy K Stump; Jennifer M Taber; Wendy Kohlmann; Samantha L Leaf; Sancy A Leachman
Journal:  J Behav Med       Date:  2015-03-31

5.  [The Research Domain Criteria (Rdoc), reductionism and clinical psychiatry].

Authors:  Luc Faucher; Simon Goyer
Journal:  Rev Synth       Date:  2016-12

6.  Could Treatment Matching Patients' Beliefs About Depression Improve Outcomes?

Authors:  Jeffrey R Vittengl; Lee Anna Clark; Michael E Thase; Robin B Jarrett
Journal:  Behav Ther       Date:  2018-12-08

7.  Testing positive for a genetic predisposition to depression magnifies retrospective memory for depressive symptoms.

Authors:  Matthew S Lebowitz; Woo-Kyoung Ahn
Journal:  J Consult Clin Psychol       Date:  2017-11

8.  Beliefs about causes of major depression: Clinical and treatment correlates among African Americans in an urban community.

Authors:  Eleanor Murphy; Sidney Hankerson
Journal:  J Clin Psychol       Date:  2017-10-27

9.  An experiment assessing effects of personalized feedback about genetic susceptibility to obesity on attitudes towards diet and exercise.

Authors:  Woo-Kyoung Ahn; Matthew S Lebowitz
Journal:  Appetite       Date:  2017-08-31       Impact factor: 3.868

Review 10.  Anticipating the Ethical Challenges of Psychiatric Genetic Testing.

Authors:  Paul S Appelbaum; Shawna Benston
Journal:  Curr Psychiatry Rep       Date:  2017-07       Impact factor: 5.285

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